Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M Hope Robinson"'
Autor:
Archana Kamalakar, Brendan Tobin, Sundus Kaimari, M Hope Robinson, Afra I Toma, Timothy Cha, Samir Chihab, Irica Moriarity, Surabhi Gautam, Pallavi Bhattaram, Shelly Abramowicz, Hicham Drissi, Andres Garcia, Levi Wood, Steven L Goudy
Publikováno v:
eLife, Vol 13 (2024)
Current treatments for congenital and acquired craniofacial (CF) bone abnormalities are limited and costly. Conventional methods involve surgical correction, short-term stabilization, and long-term bone grafting, which may include problematic allogra
Externí odkaz:
https://doaj.org/article/0089cf3ed1324a5a8e384123ccfabe55
Autor:
M. Hope Robinson, Nancy Y. Villa, David L. Jaye, Ajay K. Nooka, Alyssa Duffy, Samuel S. McCachren, Julia Manalo, Jeffrey M. Switchenko, Sierra Barnes, Sayalee Potdar, Maryam I. Azeem, Ava A. Horvat, Vaunita C. Parihar, Jingjing Gong, Yan Liang, Geoffrey H. Smith, Vikas A. Gupta, Lawrence H. Boise, Jonathan L. Kaufman, Craig C. Hofmeister, Nisha S. Joseph, Sagar Lonial, Kavita M. Dhodapkar, Madhav V. Dhodapkar
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 15 (2023)
Entry of antigen-specific T cells into human tumors is critical for immunotherapy, but the underlying mechanisms are poorly understood. Here, we combined high-dimensional spatial analyses with in vitro and in vivo modeling to study the mechanisms und
Externí odkaz:
https://doaj.org/article/4e93c2e8320c4a29894d2dbcaa88a70f
Autor:
Hyerim Kim, Yunhee Kang, Yujing Li, Li Chen, Li Lin, Nicholas D. Johnson, Dan Zhu, M. Hope Robinson, Leon McSwain, Benjamin G. Barwick, Xianrui Yuan, Xinbin Liao, Jie Zhao, Zhiping Zhang, Qiang Shu, Jianjun Chen, Emily G. Allen, Anna M. Kenney, Robert C. Castellino, Erwin G. Van Meir, Karen N. Conneely, Paula M. Vertino, Peng Jin, Jian Li
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-25 (2021)
Abstract Background Medulloblastoma (MB) is the most common malignant pediatric brain tumor that originates in the cerebellum and brainstem. Frequent somatic mutations and deregulated expression of epigenetic regulators in MB highlight the substantia
Externí odkaz:
https://doaj.org/article/2c470edd61e44204bdc75332b31115e7
Autor:
Victor Maximov, Zhihong Chen, Yun Wei, M. Hope Robinson, Cameron J. Herting, Nithya S. Shanmugam, Vasilisa A. Rudneva, Kelly C. Goldsmith, Tobey J. MacDonald, Paul A. Northcott, Dolores Hambardzumyan, Anna M. Kenney
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The Sonic Hedgehog subgroup of medulloblastoma are characterised by the high infiltration of tumour-associated macrophages (TAMs). Here, the authors show that TAM numbers in patients are associated with better prognosis and that, consistently, in a m
Externí odkaz:
https://doaj.org/article/8d9bcf366d79419c9f9e965c3c18cd6f
Autor:
Shoeb Lallani, Renee Read, Anna Kenney, Victor Maximov, Michael D. Taylor, M. Hope Robinson, Hamza Farooq
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Medulloblastoma is a malignant pediatric tumor that arises from neural progenitors in the cerebellum. Despite a five-year survival rate of ~70%, nearly all patients incur adverse side effects from current treatment strategies that drastically impact
Autor:
Erwin G. Van Meir, Jian Li, Qiang Shu, Karen N. Conneely, Emily G. Allen, Dan Zhu, Yunhee Kang, Li Chen, Jie Zhao, Robert C. Castellino, Li Lin, Yujing Li, M. Hope Robinson, Peng Jin, Leon F. McSwain, Benjamin G. Barwick, Paula M. Vertino, Anna Kenney, Zhiping Zhang, Jianjun Chen, Xianrui Yuan, Nicholas D. Johnson, Xinbin Liao, Hyerim Kim
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-25 (2021)
Genome Biology
Genome Biology
BackgroundMedulloblastoma (MB) is the most common malignant pediatric brain tumor that originates in the cerebellum and brainstem. Frequent somatic mutations and deregulated expression of epigenetic regulators in MB highlight the substantial role of
Autor:
Hyerim Kim, Yunhee Kang, Yujing Li, Chen, Li, Lin, Li, Johnson, Nicholas D., Zhu, Dan, M. Hope Robinson, McSwain, Leon, Barwick, Benjamin G., Xianrui Yuan, Xinbin Liao, Zhao, Jie, Zhiping Zhang, Shu, Qiang, Jianjun Chen, Allen, Emily G., Kenney, Anna M., Castellino, Robert C., Van Meir, Erwin G., Conneely, Karen N., Vertino, Paula M., Jin, Peng, Li, Jian
Additional file 18. Review history.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6570839e5eafc03c7f189bb521484aef
Autor:
Juan C. Vasquez, Akhilesh Kaushal, Kavita M. Dhodapkar, M. Hope Robinson, José E. Velázquez Vega, Matthew Schniederjan, Tobey J. MacDonald
Publikováno v:
Journal for Immunotherapy of Cancer
Brain tumors are the leading cause of cancer-related mortality in children and have distinct genomic and molecular features compared with adult glioma. However, the properties of immune cells in these tumors has been vastly understudied compared with
Autor:
Dolores Hambardzumyan, Kelly C. Goldsmith, M. Hope Robinson, Victor Maximov, Vasilisa A. Rudneva, Zhihong Chen, Anna Kenney, Paul A. Northcott, Cameron Herting, Nithya S. Shanmugam, Tobey J. MacDonald, Yun Wei
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Medulloblastoma, which is the most common malignant paediatric brain tumour, has a 70% survival rate, but standard treatments often lead to devastating life-long side effects and recurrence is fatal. One of the emerging strategies in the search for t
Publikováno v:
Molecular and Cellular Biology. 39
Cerebellar development is a highly regulated process involving numerous factors acting with high specificity, both temporally and by location. Part of this process involves extensive proliferation of cerebellar granule neuron precursors (CGNPs) induc