Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M Hoitsma"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The organization of DNA into nucleosomes is a ubiquitous and ancestral feature that was once thought to be exclusive to the eukaryotic domain of life. Intriguingly, several representatives of the Nucleocytoplasmic Large DNA Viruses (NCLDV) e
Externí odkaz:
https://doaj.org/article/88ef5ef6ba9f49298d59250cc22dfd0c
Autor:
Tyler M. Weaver, Nicole M. Hoitsma, Jonah J. Spencer, Lokesh Gakhar, Nicholas J. Schnicker, Bret D. Freudenthal
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
AP endonuclease 1 (APE1) processes genomic AP sites during base excision repair. Here, the authors determine the structural mechanism used by APE1 to process nucleosomal AP sites, providing new insight into DNA repair in chromatin.
Externí odkaz:
https://doaj.org/article/03554504093a407299ffc39f4e3f6c96
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3293-3302 (2021)
Ribonucleotides (rNTPs) are predicted to be incorporated into the genome at a rate of up to 3 million times per cell division, making rNTPs the most common non-standard nucleotide in the human genome. Typically, misinserted ribonucleotides are repair
Externí odkaz:
https://doaj.org/article/1cb17b3695494a05a1c0d6398ac3bf99
Autor:
Nicole M. Hoitsma, Jessica Norris, Thu H. Khoang, Vikas Kaushik, Edwin Antony, Mark Hedglin, Bret D. Freudenthal
1.AbstractMany types of DNA damage stall replication fork progression, including abasic sites. AP-Endonuclease 1 (APE1) has been shown to cleave abasic sites in ssDNA substrates. Importantly, APE1 cleavage of ssDNA at a replication fork has significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05cf5a2dbed225bf10eca611146bf082
https://doi.org/10.1101/2022.08.22.504733
https://doi.org/10.1101/2022.08.22.504733
Publikováno v:
International Journal of Antimicrobial Agents. 23:325-331
Obtaining diagnostic microbiological cultures before initiating empirical antimicrobial therapy is part of the diagnostic work-up of intensive care patients with a clinical suspicion of infection. However, it is unknown to what extent these cultures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e80a029e76638dd1eb27716f705bcf0
https://doi.org/10.1016/j.ijantimicag.2003.08.013
https://doi.org/10.1016/j.ijantimicag.2003.08.013
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