Zobrazeno 1 - 10
of 3 133
pro vyhledávání: '"M Hauser"'
Autor:
S. Schöngart, L. Gudmundsson, M. Hauser, P. Pfleiderer, Q. Lejeune, S. Nath, S. I. Seneviratne, C.-F. Schleussner
Publikováno v:
Geoscientific Model Development, Vol 17, Pp 8283-8320 (2024)
Emulators of Earth system models (ESMs) are statistical models that approximate selected outputs of ESMs. Owing to their runtime efficiency, emulators are especially useful when large amounts of data are required, for example, for in-depth exploratio
Externí odkaz:
https://doaj.org/article/f7f88b6b277b46e297d1a66e34ad5d72
Autor:
Rudhab Bahabry, Rebecca M. Hauser, Richard G. Sánchez, Silvienne Sint Jago, Lara Ianov, Remy J. Stuckey, R. Ryley Parrish, Lawrence Ver Hoef, Farah D. Lubin
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106638- (2024)
Temporal lobe epilepsy (TLE) is a type of focal epilepsy characterized by spontaneous recurrent seizures originating from the hippocampus. The epigenetic reprogramming hypothesis of epileptogenesis suggests that the development of TLE is associated w
Externí odkaz:
https://doaj.org/article/38770ea5960840009a2f4a3bb67c2e09
Autor:
P. M. Forster, C. Smith, T. Walsh, W. F. Lamb, R. Lamboll, B. Hall, M. Hauser, A. Ribes, D. Rosen, N. P. Gillett, M. D. Palmer, J. Rogelj, K. von Schuckmann, B. Trewin, M. Allen, R. Andrew, R. A. Betts, A. Borger, T. Boyer, J. A. Broersma, C. Buontempo, S. Burgess, C. Cagnazzo, L. Cheng, P. Friedlingstein, A. Gettelman, J. Gütschow, M. Ishii, S. Jenkins, X. Lan, C. Morice, J. Mühle, C. Kadow, J. Kennedy, R. E. Killick, P. B. Krummel, J. C. Minx, G. Myhre, V. Naik, G. P. Peters, A. Pirani, J. Pongratz, C.-F. Schleussner, S. I. Seneviratne, S. Szopa, P. Thorne, M. V. M. Kovilakam, E. Majamäki, J.-P. Jalkanen, M. van Marle, R. M. Hoesly, R. Rohde, D. Schumacher, G. van der Werf, R. Vose, K. Zickfeld, X. Zhang, V. Masson-Delmotte, P. Zhai
Publikováno v:
Earth System Science Data, Vol 16, Pp 2625-2658 (2024)
Intergovernmental Panel on Climate Change (IPCC) assessments are the trusted source of scientific evidence for climate negotiations taking place under the United Nations Framework Convention on Climate Change (UNFCCC). Evidence-based decision-making
Externí odkaz:
https://doaj.org/article/ef7ee21c7458401c81ff5b10b2209055
Autor:
Blake M. Hauser, Yuyang Luo, Anusha Nathan, Ahmad Al-Moujahed, Demetrios G. Vavvas, Jason Comander, Eric A. Pierce, Emily M. Place, Kinga M. Bujakowska, Gaurav D. Gaiha, Elizabeth J. Rossin
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Advances in gene sequencing technologies have accelerated the identification of genetic variants, but better tools are needed to understand which are causal of disease. This would be particularly useful in fields where gene therapy is a pote
Externí odkaz:
https://doaj.org/article/687636a497b74f41b978034f522f3392
Autor:
D. L. Schumacher, M. Zachariah, F. Otto, C. Barnes, S. Philip, S. Kew, M. Vahlberg, R. Singh, D. Heinrich, J. Arrighi, M. van Aalst, M. Hauser, M. Hirschi, V. Bessenbacher, L. Gudmundsson, H. K. Beaudoing, M. Rodell, S. Li, W. Yang, G. A. Vecchi, L. J. Harrington, F. Lehner, G. Balsamo, S. I. Seneviratne
Publikováno v:
Earth System Dynamics, Vol 15, Pp 131-154 (2024)
In the 2022 summer, western–central Europe and several other regions in the northern extratropics experienced substantial soil moisture deficits in the wake of precipitation shortages and elevated temperatures. Much of Europe has not witnessed a mo
Externí odkaz:
https://doaj.org/article/ea6d0dcff9b84f709c04d1f43d15a86c
Autor:
Eike-Christian Wamhoff, Larance Ronsard, Jared Feldman, Grant A. Knappe, Blake M. Hauser, Anna Romanov, James Brett Case, Shilpa Sanapala, Evan C. Lam, Kerri J. St. Denis, Julie Boucau, Amy K. Barczak, Alejandro B. Balazs, Michael S. Diamond, Aaron G. Schmidt, Daniel Lingwood, Mark Bathe
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Protein-based virus-like particles (P-VLPs) are commonly used to spatially organize antigens and enhance humoral immunity through multivalent antigen display. However, P-VLPs are thymus-dependent antigens that are themselves immunogenic and
Externí odkaz:
https://doaj.org/article/a903d94958bc48e7ac6e79ace0aa2f9a
Autor:
Caroline S. Meier, Marco Pagni, Sophie Richard, Konrad Mühlethaler, João M. G. C. F. Almeida, Gilles Nevez, Melanie T. Cushion, Enrique J. Calderón, Philippe M. Hauser
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Surface antigenic variation is crucial for major pathogens that infect humans. To escape the immune system, they exploit various mechanisms. Understanding these mechanisms is important to better prevent and fight the deadly diseases caused.
Externí odkaz:
https://doaj.org/article/38540847963544e585f51e93cfe07bc9
Autor:
P. M. Forster, C. J. Smith, T. Walsh, W. F. Lamb, R. Lamboll, M. Hauser, A. Ribes, D. Rosen, N. Gillett, M. D. Palmer, J. Rogelj, K. von Schuckmann, S. I. Seneviratne, B. Trewin, X. Zhang, M. Allen, R. Andrew, A. Birt, A. Borger, T. Boyer, J. A. Broersma, L. Cheng, F. Dentener, P. Friedlingstein, J. M. Gutiérrez, J. Gütschow, B. Hall, M. Ishii, S. Jenkins, X. Lan, J.-Y. Lee, C. Morice, C. Kadow, J. Kennedy, R. Killick, J. C. Minx, V. Naik, G. P. Peters, A. Pirani, J. Pongratz, C.-F. Schleussner, S. Szopa, P. Thorne, R. Rohde, M. Rojas Corradi, D. Schumacher, R. Vose, K. Zickfeld, V. Masson-Delmotte, P. Zhai
Publikováno v:
Earth System Science Data, Vol 15, Pp 2295-2327 (2023)
Intergovernmental Panel on Climate Change (IPCC) assessments are the trusted source of scientific evidence for climate negotiations taking place under the United Nations Framework Convention on Climate Change (UNFCCC), including the first global stoc
Externí odkaz:
https://doaj.org/article/e952f4d56e24497ca4d925f11b488255
Publikováno v:
Earth System Dynamics, Vol 14, Pp 485-505 (2023)
It is now certain that human-induced climate change is increasing the incidence of extreme temperature, precipitation and drought events globally. A critical aspect of these extremes is their potential concurrency that can result in substantial impac
Externí odkaz:
https://doaj.org/article/5ba34ac2c95c4897b4355b240fd9fb3b
Autor:
Etsuro Nanishi, Francesco Borriello, Hyuk-Soo Seo, Timothy R. O’Meara, Marisa E. McGrath, Yoshine Saito, Jing Chen, Joann Diray-Arce, Kijun Song, Andrew Z. Xu, Soumik Barman, Manisha Menon, Danica Dong, Timothy M. Caradonna, Jared Feldman, Blake M. Hauser, Aaron G. Schmidt, Lindsey R. Baden, Robert K. Ernst, Carly Dillen, Jingyou Yu, Aiquan Chang, Luuk Hilgers, Peter Paul Platenburg, Sirano Dhe-Paganon, Dan H. Barouch, Al Ozonoff, Ivan Zanoni, Matthew B. Frieman, David J. Dowling, Ofer Levy
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Development of SARS-CoV-2 vaccines that protect vulnerable populations is a public health priority. Here, we took a systematic and iterative approach by testing several adjuvants and SARS-CoV-2 antigens to identify a combination that elicits
Externí odkaz:
https://doaj.org/article/1cc5213015424ab48d02bcd22247ff42