Zobrazeno 1 - 10
of 313
pro vyhledávání: '"M Harold, Laughlin"'
Autor:
Bradley J. Baranowski, Matti D. Allen, Jennifer N.K. Nyarko, R. Scott Rector, Jaume Padilla, Darrell D. Mousseau, Christoph D. Rau, Yibin Wang, M. Harold Laughlin, Craig A. Emter, Rebecca E.K. MacPherson, T. Dylan Olver
Publikováno v:
JCI Insight, Vol 6, Iss 10 (2021)
Individuals with heart failure (HF) frequently present with comorbidities, including obesity, insulin resistance, hypertension, and dyslipidemia. Many patients with HF experience cardiogenic dementia, yet the pathophysiology of this disease remains p
Externí odkaz:
https://doaj.org/article/c9b519b32daa4129a242729f4019a246
Autor:
T. Dylan Olver, Jessica A. Hiemstra, Jenna C. Edwards, Todd R. Schachtman, Cheryl M. Heesch, Paul J. Fadel, M. Harold Laughlin, Craig A. Emter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 11 (2017)
BackgroundPostmenopausal women represent the largest cohort of patients with heart failure with preserved ejection fraction, and vascular dementia represents the most common form of dementia in patients with heart failure with preserved ejection frac
Externí odkaz:
https://doaj.org/article/24df2e1448ec451aa6136ec095e209fd
Autor:
T. Dylan Olver, Diana Klakotskaia, Brian S. Ferguson, Jessica A. Hiemstra, Todd R. Schachtman, M. Harold Laughlin, Craig A. Emter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 5 (2016)
BackgroundCognitive impairment in the setting of heart failure with preserved ejection fraction remains poorly understood. Using aortic‐banded miniature swine displaying pathological features of human heart failure with preserved ejection fraction,
Externí odkaz:
https://doaj.org/article/465dadbe25a046bd96b1297f53c0997e
Publikováno v:
Journal of Clinical & Translational Endocrinology, Vol 1, Iss 1, Pp e27-e30 (2014)
The purpose was to test the hypothesis that adipocytes from obese rats would exert pro-atherogenic paracrine effects on cultured endothelial cells compared to adipocytes from lean rats, and that the adverse obesity-associated paracrine effects of adi
Externí odkaz:
https://doaj.org/article/91e203516c5b4262805e69c15b56d060
Publikováno v:
J Pathol
Duchenne muscular dystrophy (DMD) is a muscle-wasting disease caused by dystrophin deficiency. Vascular dysfunction has been suggested as an underlying pathogenic mechanism in DMD. However, this has not been thoroughly studied in a large animal model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7712618003ebf63f2b3363454f8f4513
https://europepmc.org/articles/PMC8713812/
https://europepmc.org/articles/PMC8713812/
Autor:
Jennifer N. K. Nyarko, Darrell D. Mousseau, Craig A. Emter, Bradley J. Baranowski, Matti D. Allen, M. Harold Laughlin, Christoph Rau, Rebecca E. K. MacPherson, Jaume Padilla, Yibin Wang, T. Dylan Olver, R. Scott Rector
Publikováno v:
JCI Insight
JCI insight, vol 6, iss 10
JCI insight, vol 6, iss 10
Individuals with heart failure (HF) frequently present with comorbidities, including obesity, insulin resistance, hypertension, and dyslipidemia. Many patients with HF experience cardiogenic dementia, yet the pathophysiology of this disease remains p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707b0664497f63612c0c274eb7e00b47
https://doi.org/10.1172/jci.insight.143141
https://doi.org/10.1172/jci.insight.143141
Autor:
Craig A. Emter, Jenna C. Edwards, T. Dylan Olver, Michael A. Hill, Jessica A. Hiemstra, M. Harold Laughlin, Pamela K. Thorne, Brian S. Ferguson
Publikováno v:
Journal of Applied Physiology. 125:86-96
Conventional treatments have failed to improve the prognosis of heart failure with preserved ejection fraction (HFpEF) patients. Thus, the purpose of this study was to determine the therapeutic efficacy of chronic interval exercise training (IT) on l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af99ed07e40201fb21833ded0b87ac8
https://doi.org/10.1152/japplphysiol.01138.2017
https://doi.org/10.1152/japplphysiol.01138.2017
Autor:
Hsiao T. Yang, Jeffrey L. Jasperse, Matthew W. McDonald, Todd R. Schachtman, C.W. James Melling, T. Dylan Olver, Diana Klakotskaia, Rachel A. Richardson, Craig A. Emter, M. Harold Laughlin
Publikováno v:
Journal of Applied Physiology. 122:1040-1050
This study tested the hypotheses that obesity-induced decrements in insulin-stimulated cerebrovascular vasodilation would be normalized with acute endothelin-1a receptor antagonism and that treatment with a physical activity intervention restores vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403e4cda7d72f5d0abe68d1f823c0966
https://doi.org/10.1152/japplphysiol.00811.2016
https://doi.org/10.1152/japplphysiol.00811.2016
Autor:
Jessica A. Hiemstra, T. Dylan Olver, Jenna C. Edwards, M. Harold Laughlin, Brian S. Ferguson, Craig A. Emter
Publikováno v:
Journal of Applied Physiology. 122:423-429
During cardiac surgery, specifically sternotomy, cranial hypoperfusion is linked to cerebral ischemia, increased risk of perioperative watershed stroke, and other neurocognitive complications. The purpose of this study was to retrospectively examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86ef8a6353bd0a9efffce70e7db4b08
https://doi.org/10.1152/japplphysiol.00817.2016
https://doi.org/10.1152/japplphysiol.00817.2016
Autor:
Rory P. Cunningham, E. Matthew Morris, John P. Thyfault, M. Harold Laughlin, Melissa A. Linden, Ryan D. Sheldon, Grace M. Meers, Jamal A. Ibdah, R. Scott Rector
Publikováno v:
Am J Physiol Endocrinol Metab
Dysregulated mitochondrial quality control leads to mitochondrial functional impairments that are central to the development and progression of hepatic steatosis to nonalcoholic steatohepatitis (NASH). Here, we identify hepatocellular localized endot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c9f40aee67ae428d72bb08f43be9b0
https://pubmed.ncbi.nlm.nih.gov/31361543
https://pubmed.ncbi.nlm.nih.gov/31361543