Výsledky vyhledávání

Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines

Autor: Dan C. DeBorde, Hunein F. Maassab, Robert F. Betts, Brian R. Murphy, Stephen D. Sears, D Herrington, M L Clements, M H Snyder, Raphael Dolin, E L Tierney

Publikováno v: Journal of Virology. 62:488-495

Clinical studies previously demonstrated that live influenza A virus vaccines derived by genetic reassortment from the mating of influenza A/Ann Arbor/6/60 (H2N2) cold-adapted (ca) donor virus with epidemic wild-type influenza A viruses are reproduci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19875cd3bf0aaabb13e8543b20473d09
https://doi.org/10.1128/jvi.62.2.488-495.1988

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Analysis of immunoglobulin G antibody responses after administration of live and inactivated influenza A vaccine indicates that nasal wash immunoglobulin G is a transudate from serum

Autor: M L Clements, D K Wagner, Brian R. Murphy, D L Nelson, C B Reimer, M H Snyder

Publikováno v: Journal of Clinical Microbiology. 25:559-562

Following intranasal administration of live influenza A virus vaccine or parenteral inoculation of inactivated influenza virus vaccine, immunoglobulin antibody to the influenza virus hemagglutinin was detected in nasal wash specimens from adult volun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e313f12eede03668a16f70ce7b3ae7ae
https://doi.org/10.1128/jcm.25.3.559-562.1987

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Serum immunoglobulin G antibody subclass response to respiratory syncytial virus F and G glycoproteins after first, second, and third infections

Autor: Larry J. Anderson, Frederick W. Henderson, P Muelenaer, C B Reimer, Edward E. Walsh, Brian R. Murphy, M H Snyder, D K Wagner, D L Nelson

Publikováno v: Journal of Clinical Microbiology. 27:589-592

Serum samples from 31 children who experienced two or three infections with respiratory syncytial virus (RSV) in the first four years of life were tested in an enzyme-linked immunosorbent assay to examine the immunoglobulin G (IgG) subclass responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e2df96e418409d517a37c4a55677d9
https://doi.org/10.1128/jcm.27.3.589-592.1989

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Determination of antibody response to influenza virus surface glycoproteins by kinetic enzyme-linked immunosorbent assay

Autor: Brian R. Murphy, M H Snyder, S Banks

Publikováno v: Journal of Clinical Microbiology. 26:2034-2040

We modified an existing enzyme-linked immunosorbent assay (ELISA) to be able to use new spectrophotometers which can measure the rate of color development in microtiter wells. This new kinetic-based ELISA (KELISA) required only a single dilution of s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086a3f998573de0876267489e885d831
https://doi.org/10.1128/jcm.26.10.2034-2040.1988

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Attenuation of wild-type human influenza A virus by acquisition of the PA polymerase and matrix protein genes of influenza A/Ann Arbor/6/60 cold-adapted donor virus

Autor: M L Clements, H F Maassab, Brian R. Murphy, D De Borde, M H Snyder

Publikováno v: Journal of Clinical Microbiology. 22:719-725

Wild-type influenza A viruses can be attenuated for humans by the acquisition of genes from the A/Ann Arbor/6/60 cold-adapted (ca) donor virus. Six-gene reassortants, that is, viruses containing the hemagglutinin and neuraminidase surface glycoprotei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deadffc7628453fb3766b5ca5ef9ab05
https://doi.org/10.1128/jcm.22.5.719-725.1985

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Evaluation of live avian-human reassortant influenza A H3N2 and H1N1 virus vaccines in seronegative adult volunteers

Autor: Raphael Dolin, M H Snyder, Robert F. Betts, E L Tierney, Brian R. Murphy, M L Clements, A J Buckler-White

Publikováno v: Journal of Clinical Microbiology. 23:852-857

An avian-human reassortant influenza A virus deriving its genes coding for the hemagglutinin and neuraminidase from the human influenza A/Washington/897/80 (H3N2) virus and its six "internal" genes from the avian influenza A/Mallard/NY/6750/78 (H2N2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51908f5633d6e10b36c1bda67ec4641
https://doi.org/10.1128/jcm.23.5.852-857.1986

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Comparison by studies in squirrel monkeys, chimpanzees, and adult humans of avian-human influenza A virus reassortants derived from different avian influenza virus donors

Autor: Brian R. Murphy, Eveline L. Tierney, D Herrington, M L Clements, W. T. London, M H Snyder

Publikováno v: Journal of Clinical Microbiology. 24:467-469

We evaluated the abilities of three different avian influenza A viruses to attenuate the wild-type human influenza A/Korea/1/82 (H3N2) virus in squirrel monkeys, chimpanzees, and adult seronegative human volunteers. Two of these, avian influenza A/Ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0efa6874be7ae6bcc47b47d9cdfc66a
https://doi.org/10.1128/jcm.24.3.467-469.1986

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Comparison of the virologic and immunologic responses of volunteers to live avian-human influenza A H3N2 reassortant virus vaccines derived from two different avian influenza virus donors

Autor: M H Snyder, K Christina, Brian R. Murphy, Mary Lou Clements, Stephen D. Sears

We compared the abilities of the six internal RNA segments of two avian influenza viruses, A/Mallard/Alberta/88/76 (H3N8) and A/Mallard/NY/6750/78 (H2N2), to confer attenuation on wild-type human influenza A/Bethesda/1/85 (H3N2) virus in seronegative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750b0af822cfd2094c39940286f52c29
https://europepmc.org/articles/PMC267272/

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