Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M H, Zile"'
Autor:
M, Griffith, M H, Zile
Publikováno v:
Teratology. 62(2)
Retinoic acid (RA) is necessary for normal differentiation of the tail bud into the secondary neural tube. Excess RA, however, is teratogenic and causes neural tube defects (NTDs). The way in which RA modulates secondary neurulation is unclear but pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e4b355ee41c7ee1037720592a421dba
https://pubmed.ncbi.nlm.nih.gov/10931510
https://pubmed.ncbi.nlm.nih.gov/10931510
Autor:
M. H. Zile
Publikováno v:
Retinoids ISBN: 9783642636141
The importance of the micronutrient vitamin A throughout the life cycle has been well established in numerous studies (Moore 1957; Wolf 1984). It has more recently become quite clear that the requirement for vitamin A begins with embryonic life, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f8bf6f12b8ca926e385c7c197f5bc23
https://doi.org/10.1007/978-3-642-58483-1_15
https://doi.org/10.1007/978-3-642-58483-1_15
Publikováno v:
International journal of cancer. 75(3)
We examined the effect of consumption of graded increases of dietary fiber (soft white wheat bran) on the development of mammary gland carcinomas in intact female Sprague-Dawley rats during the promotion stage of carcinogenesis, induced with 7,12-dim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6b892d800f8eb87731aa1125dc45383
https://pubmed.ncbi.nlm.nih.gov/9455806
https://pubmed.ncbi.nlm.nih.gov/9455806
Publikováno v:
Alcoholism, clinical and experimental research. 21(6)
The effect of ethanol on early avian cardiovascular development was investigated in stage 8 quail embryos grown in culture for 24 hr. When the culture medium contained 1% ethanol, 50% of the embryos developed abnormalities of the cardiovascular syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d17e5217df2c9c6cfa8b0270a8e9f4bd
https://pubmed.ncbi.nlm.nih.gov/9309328
https://pubmed.ncbi.nlm.nih.gov/9309328
Publikováno v:
Cancer research. 55(23)
Nuclear retinoic acid receptor beta (RAR-beta) expression decreases in human premalignant oral lesions (POLs). RAR-beta suppression could result from a decrease in the cellular level of retinoids because RAR-beta gene transcription is enhanced by ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a6402fee8f6d5f6cc289685c036678a
https://pubmed.ncbi.nlm.nih.gov/7585623
https://pubmed.ncbi.nlm.nih.gov/7585623
Autor:
T H, Gerlach, M H, Zile
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 5(1)
We recently demonstrated a rapid up-regulation of serum retinol-retinol binding protein-transthyretin concentration in rats with short-term acute renal failure. We examine the effect of retinoic acid and apo-retinol binding protein (apo-RBP) on the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64b04fce0bee089dbf6fce0a4bf647d4
https://pubmed.ncbi.nlm.nih.gov/1991596
https://pubmed.ncbi.nlm.nih.gov/1991596
Publikováno v:
Journal of Biological Chemistry. 257:3537-3543
The metabolites of all-trans-[3H]retinoic acid were studied in the rat bile. In the bile duct cannulated rat 80 to 86% of the dose is excreted into the bile within 24 h after the intravenous administration of either a physiological or pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c6dca442969a5195b4598e938ba462
https://doi.org/10.1016/s0021-9258(18)34812-9
https://doi.org/10.1016/s0021-9258(18)34812-9
Autor:
M H Zile, M E Cullum
Publikováno v:
Journal of Biological Chemistry. 260:10590-10596
The kinetics and metabolism of physiological doses of all-trans-retinoic acid were examined in blood and small intestinal mucosa of vitamin A-depleted rats. A major portion of intrajugularly injected retinoic acid is rapidly (within 2 min) sequestere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdde67b33861ba198c3530780fe5073b
https://doi.org/10.1016/s0021-9258(19)85126-8
https://doi.org/10.1016/s0021-9258(19)85126-8
Publikováno v:
Journal of Biological Chemistry. 257:3544-3550
The metabolites of all-trans-[3H]retinoic acid appearing in the intestines of bile duct-cannulated rats were compared to those of similarly treated intact rats. 2.4% of administered radioactivity was found in the small intestines of bile duct-cannula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30550d2819fd98f9ab486fb633460378
https://doi.org/10.1016/s0021-9258(18)34813-0
https://doi.org/10.1016/s0021-9258(18)34813-0
Publikováno v:
Biochimica et biophysica acta. 926(3)
Chronic dietary administration of 3,3',4,4',5,5'-hexabromobiphenyl (HBB), 1 mg/kg diet, caused a decrease in retinol (20-fold) and retinyl esters (23-fold) in the livers of female rats, but resulted in a 6.4-fold increase in retinol and 7.4-fold incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c427a9907a9c8f500f8555591744f7c7
https://pubmed.ncbi.nlm.nih.gov/2825801
https://pubmed.ncbi.nlm.nih.gov/2825801