Zobrazeno 1 - 10
of 10
pro vyhledávání: '"M H, Mudd"'
Publikováno v:
Journal of Bacteriology. 180:4856-4864
Oxidative stress response in pathogenic mycobacteria is believed to be of significance for host-pathogen interactions at various stages of infection. It also plays a role in determining the intrinsic susceptibility to isoniazid in mycobacterial speci
Publikováno v:
Scopus-Elsevier
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A distinguishing feature of Pseudomonas aeruginosa isolates from cystic fibrosis (CF) patients is their mucoid, exopolysaccharide alginate-overproducing phenotype. One mechanism of conversion to mucoidy is based on mutations in the algU mucABCD clust
Autor:
Thomas R. Garbe, Wolfgang J. Philipp, M H Mudd, Subramanian Dhandayuthapani, Vojo Deretic, Beate Heym, R. Curcic, Stewart T. Cole, Laura E. Via
Publikováno v:
Molecular Microbiology. 17:889-900
The systems participating in detoxification of reactive oxygen intermediates in Mycobacterium tuberculosis are believed to play a dual role in the biology of this highly adapted human pathogen: (i) they may contribute to the survival of this bacteriu
Publikováno v:
Scopus-Elsevier
Conversion to mucoidy, caused by the overproduction of the exopolysaccharide alginate in laboratory and cystic fibrosis strains of Pseudomonas aeruginosa, can occur via frameshift or nonsense mutations in the second gene of the algU mucA mucB cluster
Publikováno v:
Scopus-Elsevier
In contrast to the intact oxyR gene (a homolog of the central regulator of peroxide stress response in enteric bacteria) in Mycobacterium leprae, this gene is inactive in all strains of M. tuberculosis. In both species, oxyR is divergently transcribe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9cc561d1bbb2f968bc1dbea16324ab
https://europepmc.org/articles/PMC178979/
https://europepmc.org/articles/PMC178979/
Publikováno v:
Scopus-Elsevier
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Alginate production in mucoid Pseudomonas aeruginosa isolates from cystic fibrosis patients is under direct control by AlgU, the P. aeruginosa equivalent of the extreme heat shock sigma factor sigma(E) in gram-negative bacteria, and AlgR, a response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f9df910d7c8e14b18f24dd15c21117
https://europepmc.org/articles/PMC178678/
https://europepmc.org/articles/PMC178678/
Publikováno v:
Scopus-Elsevier
A putative two-component system, mtrA-mtrB, was isolated from M. tuberculosis H37Rv by using phoB from Pseudomonas aeruginosa as a hybridization probe. The predicted gene product of mtrA displayed high similarity with typical response regulators, inc
Publikováno v:
Scopus-Elsevier
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ResearcherID
Conversion to a mucoid, exopolysaccharide alginate-overproducing phenotype in Pseudomonas aeruginosa is associated with chronic respiratory infections in cystic fibrosis. Mucoidy is caused by muc mutations that derepress the alternative sigma factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f021d146c9ab87102b11e83a68f74bf
https://europepmc.org/articles/PMC177686/
https://europepmc.org/articles/PMC177686/
Publikováno v:
Cellularmolecular biology research. 39(4)
Pseudomonas aeruginosa mutants that overproduce the exopolysaccharide alginate and assume mucoid phenotype are associated with the establishment of chronic respiratory disease in cystic fibrosis. The initially invading strains are nonmucoid and frequ
Autor:
M H Mudd, Michael J. Schurr, Vojo Deretic, R. Curcic, D. W. Martin, N. S. Hibler, J C Boucher
Publikováno v:
Scopus-Elsevier
Chronic respiratory complications in cystic fibrosis, compounded by recurring infections with mucoid Pseudomonas aeruginosa and the associated inflammation, are the primary cause of high mortality in this inheritable disease. Since the conversion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30370371f1d691338c84a2f7388af12
http://www.scopus.com/inward/record.url?eid=2-s2.0-14744297531&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-14744297531&partnerID=MN8TOARS