Zobrazeno 1 - 10
of 19
pro vyhledávání: '"M H, Hastings"'
SummaryThe hypothalamic suprachiasmatic nucleus (SCN) is the master mammalian circadian clock. Its cell-autonomous timing mechanism, a transcriptional/translational feedback loop (TTFL), drives daily peaks of neuronal electrical activity. Intercellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::352f73fbae3993bdae76c9c4347855a5
https://doi.org/10.1101/2023.01.16.523253
https://doi.org/10.1101/2023.01.16.523253
Publikováno v:
Healthy Ageing and Longevity ISBN: 9783031224676
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb6e9aec88a20eabca8c1bfb3fb721e7
https://doi.org/10.1007/978-3-031-22468-3_2
https://doi.org/10.1007/978-3-031-22468-3_2
Autor:
B, Guo, N, Yang, E, Borysiewicz, M, Dudek, J L, Williams, J, Li, E S, Maywood, A, Adamson, M H, Hastings, J F, Bateman, M R H, White, R P, Boot-Handford, Q J, Meng
Publikováno v:
Osteoarthritis and Cartilage
Summary Objective To define how the catabolic cytokines (Interleukin 1 (IL-1) and tumor necrosis factor alpha (TNFα)) affect the circadian clock mechanism and the expression of clock-controlled catabolic genes within cartilage, and to identify the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f84eaa518467f23536294e2d4e715e1e
https://pubmed.ncbi.nlm.nih.gov/26521744
https://pubmed.ncbi.nlm.nih.gov/26521744
Publikováno v:
Journal of neuroendocrinology. 1(5)
A high-affinity, discretely localized melatonin receptor has been characterized and mapped within the brain and pituitary of the Syrian hamster using the high specific activity ligand [(125)|]iodomelatonin and a combination of in vitro autoradiograph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46814e64f13f26dbbf8a642696e06ec5
https://pubmed.ncbi.nlm.nih.gov/19210421
https://pubmed.ncbi.nlm.nih.gov/19210421
Publikováno v:
Pathologie-biologie. 55(3-4)
The relation between circadian physiology (rest-activity and body temperature) and the growth of a grafted tumor (Glasgow osteosarcoma-GOS) was investigated in the mice with mutation of clock gene (ClockDelta19(-)) or gene controlled by the clock (Vp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2992536a48c28c46a424ae874e19f31e
https://pubmed.ncbi.nlm.nih.gov/17412525
https://pubmed.ncbi.nlm.nih.gov/17412525
Expression of mCLOCK and other circadian clock-relevant proteins in the mouse suprachiasmatic nuclei
Publikováno v:
Journal of neuroendocrinology. 15(4)
Circadian timing in mammals is based upon the cell-autonomous clockwork located in the suprachiasmatic nuclei (SCN) of the hypothalamus. It is thought to involve interlocked feedback loops in which periodic transcriptional drive to core clock genes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4304366578520cc9245b2d7528c688a0
https://pubmed.ncbi.nlm.nih.gov/12622829
https://pubmed.ncbi.nlm.nih.gov/12622829
Publikováno v:
The European journal of neuroscience. 17(4)
A mouse bearing a novel transgene encoding the human VPAC2 receptor (hVIPR; Shen et al. (2000) PNAS, 97, 11575-11580) was used to investigate circadian function in the hypothalamic suprachiasmatic nuclei (SCN). Neurons expressing hVPAC2R, detected by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fa0fa1542422966e414ede01bda1bcb7
https://pubmed.ncbi.nlm.nih.gov/12814356
https://pubmed.ncbi.nlm.nih.gov/12814356
Publikováno v:
The European journal of neuroscience. 12(12)
Precise temporal regulation of transcription is pivotal to the role of the mammalian pineal gland as a transducer of circadian and seasonal information. The circadian clock genes Per1 and Per2 encode factors implicated in temporally gated transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e9ce788b913e91d61042aeaaf8bd6f5
https://pubmed.ncbi.nlm.nih.gov/11122368
https://pubmed.ncbi.nlm.nih.gov/11122368
Publikováno v:
The European journal of neuroscience. 12(8)
The circadian clock in the hypothalamic suprachiasmatic nuclei (SCN) regulates the pattern of melatonin secretion from the pineal gland such that the duration of release reflects the length of the night. This seasonally specific endocrine cue mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de2aa820d28a9b846ac07eacda729b33
https://pubmed.ncbi.nlm.nih.gov/10971628
https://pubmed.ncbi.nlm.nih.gov/10971628
Publikováno v:
The European journal of neuroscience. 10(3)
Photic resetting of the adult mammalian circadian clock in vivo is associated with phosphorylation of the Ser133 residue of the calcium/cyclic AMP response-element binding-protein (CREB) in the retinorecipient region of the suprachiasmatic nucleus (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3cb368129300d5d1bd1a9b0c28301d9
https://pubmed.ncbi.nlm.nih.gov/9753174
https://pubmed.ncbi.nlm.nih.gov/9753174