Výsledky vyhledávání - "M H, Dreyling"

Microsatellite instability analysis in typical and progressed mantle cell lymphoma and B-cell chronic lymphocytic leukemia

Autor: L, Sanz-Vaqué, D, Colomer, F, Bosch, A, López-Guillermo, M H, Dreyling, E, Montserrat, E, Campo

Publikováno v: Haematologica. 86(2)

Microsatellite instability (MSI) is characterized by tumor-associated alterations in the germline size of microsatellite repeats caused by a reduced efficacy of the DNA mismatch repair machinery. The aim of this study was to investigate the presence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75067e5f76033b2f68abe5c8107bb990
https://pubmed.ncbi.nlm.nih.gov/11224488

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Molecular Characterization of the Translocation (10;11)(p13;q14): MLLandCALMare Fused toAF10in Morphologically Different Subsets of Acute Leukemia

Autor: C. Fonatsch, Detlef Haase, C. Schoch, M. H. Dreyling, W. Hiddemann, W.-D. Ludwig, Stefan K. Bohlander, K. Schrader, Brigitte Schlegelberger, V. Muschinsky

Publikováno v: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ISBN: 9783642621093

The t(10,11)(pl3;ql4) is a recurring translocation that has been observed in acute lymphoblastic as well as acute myeloid leukemia. A previous study revealed a MLL/AF10fusion in all cases of AML with t(10;11) and various breakpoints on chromosome 11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0167779b7d4e6d7be310e44ba3f51308
https://doi.org/10.1007/978-3-642-18156-6_4

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A biological role for deletions in chromosomal band 13q14 in mantle cell and peripheral t-cell lymphomas?

Autor: A, Rosenwald, G, Ott, A K, Krumdiek, M H, Dreyling, T, Katzenberger, J, Kalla, S, Roth, M M, Ott, H K, Müller-Hermelink

Publikováno v: Genes, chromosomescancer. 26(3)

Structural aberrations of chromosomal band 13q14 are frequent in B-cell chronic lymphocytic leukemia (B-CLL) and target a putative tumor suppressor gene in the genomic region between the RB1 gene and the genetic marker D13S25. Recently, it has been s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a0d76ebae8261558e1aaaba507ba3e70
https://pubmed.ncbi.nlm.nih.gov/10502318

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MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): both rearrangements are associated with a poor prognosis

Autor: M H, Dreyling, K, Schrader, C, Fonatsch, B, Schlegelberger, D, Haase, C, Schoch, W, Ludwig, H, Löffler, T, Büchner, B, Wörmann, W, Hiddemann, S K, Bohlander

Publikováno v: Blood. 91(12)

The translocation t(10;11)(p13;q14) has been observed in acute lymphoblastic leukemia (ALL) as well as acute myeloid leukemia (AML). A recent study showed a MLL/AF10 fusion in all cases of AML with t(10;11) and various breakpoints on chromosome 11 ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d4c938459525941eeec0d5970e6052e3
https://pubmed.ncbi.nlm.nih.gov/9616163

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Codeletion of CDKN2 and MTAP genes in a subset of non-Hodgkin's lymphoma may be associated with histologic transformation from low-grade to diffuse large-cell lymphoma

Autor: M H, Dreyling, D, Roulston, S K, Bohlander, J, Vardiman, O I, Olopade

Publikováno v: Genes, chromosomescancer. 22(1)

Identifying the various genetic alterations that contribute to lymphomagenesis is key to our improved understanding of the biological behavior of the disease. Recently, we and others have defined a tumor suppressor region on the short arm of chromoso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::845a053b02303603907e37d0ecec552b
https://pubmed.ncbi.nlm.nih.gov/9591637

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Preferential loss of expression of p16(INK4a) rather than p19(ARF) in breast cancer

Autor: A J, Brenner, A, Paladugu, H, Wang, O I, Olopade, M H, Dreyling, C M, Aldaz

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 2(12)

The tumor suppressor p16(INK4a) has been shown to be inactivated in numerous cancer lines and primary tumors. Recently, we reported loss of heterozygosity of the region in which p16(INK4a) is located in more than one-half of primary breast tumors. Ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::954c91ab0d0f28f68358de8c82bf0939
https://pubmed.ncbi.nlm.nih.gov/9816158

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Refined mapping of genomic rearrangements involving the short arm of chromosome 9 in acute lymphoblastic leukemias and other hematologic malignancies

Autor: M H, Dreyling, S K, Bohlander, M M, Le Beau, O I, Olopade

Publikováno v: Blood. 86(5)

Deletions of chromosomal band 9p21 have been detected in various tumor types as well as in more than 20% of acute lymphoblastic leukemia (ALL). These deletions frequently include the entire interferon (IFN) gene cluster as well as the methylthioadeno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4af90091a2f9ffe0a1956b3f610e6dc3
https://pubmed.ncbi.nlm.nih.gov/7544647

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Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in situ hybridization

Autor: M H, Dreyling, S K, Bohlander, M O, Adeyanju, O I, Olopade

Publikováno v: Cancer research. 55(5)

Deletions of chromosomal band 9p21 have been detected in various tumor types including melanoma, glioma, lung cancer, mesothelioma, and bladder cancer. Recently, the CDKN2 gene (p16INK4A, MTS I, CDK41) has been proposed as a candidate tumor suppresso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3c9d5c0b2081d18aebb0181b73310780
https://pubmed.ncbi.nlm.nih.gov/7867008

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