Zobrazeno 1 - 10
of 68
pro vyhledávání: '"M Grous"'
Publikováno v:
Neurogastroenterology & Motility. 3:46-52
Changes in cyclic nucleotide content arc associated with relaxation of lower esophageal sphincter (LES) smooth muscle. Although agents that increase cyclic AMP (cAMP) or cyclic CMP (cGMP) can relax the LES, relaxation produced by activation of enteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91fba9d896d793a19dc7d23af064c97f
https://doi.org/10.1111/j.1365-2982.1991.tb00046.x
https://doi.org/10.1111/j.1365-2982.1991.tb00046.x
Autor:
M Grous, M S Barnette, W. J. Price, W. E. Thompson, M. Fudge, F. C. Barone, A. F. Joslyn, H. S. Ormsbee, C. D. Manning
Publikováno v:
Neurogastroenterology & Motility. 2:65-72
Neuronal stimulation of most isolated precontracted gastrointestinal smooth muscle results in relaxation. This study examined the changes in cyclic nucleotide content associated with neuronally induced relaxation in sphincteric and nonsphincteric smo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3434166dc7b473aa3c03315795e2798
https://doi.org/10.1111/j.1365-2982.1990.tb00010.x
https://doi.org/10.1111/j.1365-2982.1990.tb00010.x
Autor:
Miriam Burman, M Grous, Mary S. Barnette, Carol D. Manning, David M Essayan, Siegfried B. Christensen, L. B. Cieslinski, Theodore J. Torphy
Publikováno v:
British Journal of Pharmacology. 128:1393-1398
1. Of the four major phosphodiesterase 4 (PDE4) subtypes, PDE4A, PDE4B and PDE4D are widely expressed in human inflammatory cells, including monocytes and T lymphocytes. We explored the functional role of these subtypes using ten subtype-selective PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51a6d705c94ad234a80956c8fada41a2
https://doi.org/10.1038/sj.bjp.0702911
https://doi.org/10.1038/sj.bjp.0702911
Autor:
M. Grous, M. S. Barnette
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 262:G144-G149
To study the potential of inflammatory mediators to alter colonic motility, we characterized the response of distal colonic smooth muscle to antigen challenge. Addition of ovalbumin to isolated segments of circular smooth muscle obtained from sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3683b2fe84af960f34ba8afbce853267
https://doi.org/10.1152/ajpgi.1992.262.1.g144
https://doi.org/10.1152/ajpgi.1992.262.1.g144
Publikováno v:
Gut. 32:4-9
Increases in cyclic adenosine monophosphate and cyclic guanosine monophosphate content accompany relaxation of isolated strips of opossum and canine lower oesophageal sphincter muscle. The aim of this investigation was to characterise these responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc37d9ec0511fa1ca52c95d25a7c4ac9
https://doi.org/10.1136/gut.32.1.4
https://doi.org/10.1136/gut.32.1.4
Publikováno v:
Biochemical Pharmacology. 40:1757-1762
Cyclic GMP has been proposed as an intracellular mediator of neuronally-induced relaxation in lower esophageal sphincter (LES) smooth muscle. If cyclic GMP is indeed an intracellular messenger, then agents that activate enteric neurons of the sphinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576c6b7887244abd55501d2ec296e2fd
https://doi.org/10.1016/0006-2952(90)90352-l
https://doi.org/10.1016/0006-2952(90)90352-l
Autor:
C D, Manning, M, Burman, S B, Christensen, L B, Cieslinski, D M, Essayan, M, Grous, T J, Torphy, M S, Barnette
Publikováno v:
British journal of pharmacology. 128(7)
1. Of the four major phosphodiesterase 4 (PDE4) subtypes, PDE4A, PDE4B and PDE4D are widely expressed in human inflammatory cells, including monocytes and T lymphocytes. We explored the functional role of these subtypes using ten subtype-selective PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c69566b42dceab27980c7f852f155e0
https://pubmed.ncbi.nlm.nih.gov/10602317
https://pubmed.ncbi.nlm.nih.gov/10602317
Autor:
D E, Griswold, E F, Webb, A M, Badger, P D, Gorycki, P A, Levandoski, M A, Barnette, M, Grous, S, Christensen, T J, Torphy
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 287(2)
The ability of the second generation phosphodiesterase 4 inhibitor SB 207499 (Ariflo), [c-4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)-r-l-cyclohexane carboxylic acid], to inhibit inflammatory cytokine production in vivo was evaluated and compared to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e27ad0460a9a5b73d7148b301eb89bc1
https://pubmed.ncbi.nlm.nih.gov/9808700
https://pubmed.ncbi.nlm.nih.gov/9808700
Autor:
M S, Barnette, S B, Christensen, D M, Essayan, M, Grous, U, Prabhakar, J A, Rush, A, Kagey-Sobotka, T J, Torphy
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(1)
First-generation phosphodiesterase 4 (PDE4) inhibitors, such as rolipram, inhibit the activation of immune and inflammatory cells. The clinical use of these compounds is limited by gastrointestinal side effects, such as increased acid secretion and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0036876e93af76566bd34c5456fe43e7
https://pubmed.ncbi.nlm.nih.gov/9435206
https://pubmed.ncbi.nlm.nih.gov/9435206
Autor:
M Grous, Mary S. Barnette
Publikováno v:
British journal of pharmacology. 111(1)
1. The ability of various phosphodiesterase (PDE) inhibitors to reduce the initial and/or late response to ovalbumin (OVA) in isolated strips of guinea-pig colonic smooth muscle from sensitized animals was examined. 2. Both the initial and late respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cf0985e2c98ca185fb1d74af370586
https://pubmed.ncbi.nlm.nih.gov/7516803
https://pubmed.ncbi.nlm.nih.gov/7516803