Zobrazeno 1 - 10
of 332
pro vyhledávání: '"M Gregory Forest"'
Autor:
Leyi Zhang, Han Cao, Karen Medlin, Jason Pearson, Andreas C. Aristotelous, Alexander Chen, Timothy Wessler, M. Gregory Forest
Publikováno v:
Viruses, Vol 16, Iss 1, p 69 (2023)
Throughout the COVID-19 pandemic, an unprecedented level of clinical nasal swab data from around the globe has been collected and shared. Positive tests have consistently revealed viral titers spanning six orders of magnitude! An open question is whe
Externí odkaz:
https://doaj.org/article/f5657257e6f04c84ad570d15232719b8
Autor:
Chantal Darquenne, Azadeh A.T. Borojeni, Mitchel J. Colebank, M. Gregory Forest, Balázs G. Madas, Merryn Tawhai, Yi Jiang
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The recent COVID-19 pandemic has propelled the field of aerosol science to the forefront, particularly the central role of virus-laden respiratory droplets and aerosols. The pandemic has also highlighted the critical need, and value for, an informati
Externí odkaz:
https://doaj.org/article/6ed1dc9e6e7d4e3e81fa2e08efa72f2b
Autor:
Matthew R. Markovetz, Ian C. Garbarine, Cameron B. Morrison, William J. Kissner, Ian Seim, M. Gregory Forest, Micah J. Papanikolas, Ronit Freeman, Agathe Ceppe, Andrew Ghio, Neil E. Alexis, Stephen M. Stick, Camille Ehre, Richard C. Boucher, Charles R. Esther, Marianne S. Muhlebach, David B. Hill
Publikováno v:
Journal of Cystic Fibrosis. 21:959-966
Mucus hyperconcentration in cystic fibrosis (CF) lung disease is marked by increases in both mucin and DNA concentration. Additionally, it has been shown that half of the mucins present in bronchial alveolar lavage fluid (BALF) from preschool-aged CF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d562eb564d7ab44b49b3eecdcbe0ec29
https://doi.org/10.1016/j.jcf.2022.04.008
https://doi.org/10.1016/j.jcf.2022.04.008
Autor:
Jay Newby, Jennifer L. Schiller, Timothy Wessler, Jasmine Edelstein, M. Gregory Forest, Samuel K. Lai
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Biological polymeric matrices often use molecular anchors, such as antibodies, to trap nanoparticulates. Here, the authors find that anchor-matrix bonds that are weak and short-lived confer superior trapping potency, contrary to the prevailing belief
Externí odkaz:
https://doaj.org/article/0a8f61c054d7499c8cfd1b1294055ed1
Autor:
Benjamin Walker, Dane Taylor, Josh Lawrimore, Caitlin Hult, David Adalsteinsson, Kerry Bloom, M Gregory Forest
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 8, p e1007124 (2019)
Our understanding of how chromosomes structurally organize and dynamically interact has been revolutionized through the lens of long-chain polymer physics. Major protein contributors to chromosome structure and dynamics are condensin and cohesin that
Externí odkaz:
https://doaj.org/article/8c4ca5008b024fc482a2954979b6fedd
Autor:
Anne M. Talkington, Morgan D. McSweeney, Timothy Wessler, Marielle K. Rath, Zibo Li, Tao Zhang, Hong Yuan, Jonathan E. Frank, M. Gregory Forest, Yanguang Cao, Samuel K. Lai
Publikováno v:
J Control Release
PEGylation is routinely used to extend the systemic circulation of various protein therapeutics and nanomedicines. Nonetheless, mounting evidence is emerging that individuals exposed to select PEGylated therapeutics can develop antibodies specific to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a16071e342a2ef36c658963c3c29f1
https://doi.org/10.1016/j.jconrel.2022.01.022
https://doi.org/10.1016/j.jconrel.2022.01.022
Publikováno v:
Multiscale Modeling & Simulation. 20:250-281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d719df4789a6325dfcb2069d202591dd
https://doi.org/10.1137/21m1401206
https://doi.org/10.1137/21m1401206
Publikováno v:
Physical Review E. 106
Synthetic and natural nanomaterials with self-propelling mechanisms continue to be explored to boost chain mobility beyond normal reptation in the crowded environments of entangled chains. Here we employ scaling theory and numerical simulations to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fb5e91cc6284a90d04516dbbfe79b8
https://doi.org/10.1103/physreve.106.l022501
https://doi.org/10.1103/physreve.106.l022501
Autor:
Jason Pearson, Timothy Wessler, Alex Chen, Richard C. Boucher, Ronit Freeman, Samuel K. Lai, Raymond Pickles, M. Gregory Forest
Publikováno v:
Journal of Theoretical Biology. 565:111470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c41ce6ed4e4f791b9cf6ed187b34ed7f
https://doi.org/10.1016/j.jtbi.2023.111470
https://doi.org/10.1016/j.jtbi.2023.111470
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 8, p e1004872 (2016)
A multi-mode nonlinear constitutive model for mucus is constructed directly from micro- and macro-rheology experimental data on cell culture mucus, and a numerical algorithm is developed for the culture geometry and idealized cilia driving conditions
Externí odkaz:
https://doaj.org/article/52db15e828c542008553a6dc4f2081e1