Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M Gabriela Reyes"'
Autor:
Philippe Huot, Tom H Johnston, Michael N Gandy, M Gabriela Reyes, Susan H Fox, Matthew J Piggott, Jonathan M Brotchie
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45587 (2012)
The wearing-OFF phenomenon is a common motor complication of chronic L-3,4-dihydroxyphenylalanine (L-DOPA) therapy for Parkinson's disease. We recently described the discovery of UWA-101, a dual serotonin (SERT) and dopamine (DAT) transporter inhibit
Externí odkaz:
https://doaj.org/article/b378e06c8da84467a2309cddd24be4f5
Autor:
James B Koprich, Tom H Johnston, Philippe Huot, M Gabriela Reyes, Maria Espinosa, Jonathan M Brotchie
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17698 (2011)
The pathological hallmarks of Parkinson's disease (PD) are degeneration of dopamine (DA) neurons of the substantia nigra (SN) and the presence of alpha-synuclein (α-syn)-rich Lewy bodies in DA cells that remain. To model these aspects of the disease
Externí odkaz:
https://doaj.org/article/cd191fa5f85f401ab1b00e50f9b664c1
Autor:
Katie D. Lewis, Philippe Huot, Susan H. Fox, James B. Koprich, Matthew J. Piggott, Jonathan M. Brotchie, M. Gabriela Reyes, Tom H. Johnston
Publikováno v:
Neuropharmacology. 82
L-3,4-Dihydroxyphenylalanine (L-DOPA) is the most effective treatment for Parkinson's disease (PD), but its long-term administration is complicated by wearing-off and dyskinesia. UWA-101, a dual, equipotent inhibitor of dopamine (DAT) and serotonin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330b99adc1e520ed7d512fb9096036bf
https://pubmed.ncbi.nlm.nih.gov/24447715
https://pubmed.ncbi.nlm.nih.gov/24447715
Publikováno v:
Molecular Neurodegeneration, Vol 5, Iss 1, p 43 (2010)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background The pathological hallmarks of Parkinson's disease (PD) include the presence of alpha-synuclein (α-syn) rich Lewy bodies and neurites and the loss of dopaminergic (DA) neurons of the substantia nigra (SN). Animal models of PD based on vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74087a82f41b75cab3212dc75d2c99bb
http://www.molecularneurodegeneration.com/content/5/1/43
http://www.molecularneurodegeneration.com/content/5/1/43
Autor:
Jonathan M. Brotchie, Tom H. Johnston, Maria C. Espinosa, M. Gabriela Reyes, James B. Koprich, Philippe Huot
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 3, p e17698 (2011)
PLoS ONE, Vol 6, Iss 3, p e17698 (2011)
The pathological hallmarks of Parkinson's disease (PD) are degeneration of dopamine (DA) neurons of the substantia nigra (SN) and the presence of alpha-synuclein (α-syn)-rich Lewy bodies in DA cells that remain. To model these aspects of the disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217f3d9db4e658c98db21398e4dd3c3b
https://doi.org/10.1371/journal.pone.0017698
https://doi.org/10.1371/journal.pone.0017698