Zobrazeno 1 - 10
of 40
pro vyhledávání: '"M G Spiridonova"'
Publikováno v:
Russian Journal of Genetics. 49:457-463
Publikováno v:
Генетика. 49:523-530
Type-1recessive congenital methemoglobinemia (RCM) is a rare autosomal disease characterized by a deficiency of the soluble form of nicotineamide adenine dinucleotide (NADH)-cytochrome b5 reductase (b5R) and clinically manifests as cyanosis of skin a
Autor:
E. A. Trifonova, T. V. Gabidulina, Vadim Stepanov, V. P. Puzyrev, F. D. Urnov, M. G. Spiridonova
Publikováno v:
Russian Journal of Genetics. 48:1035-1047
Analysis of the genome-specific linkage disequilibrium patterns in certain populations is a highly promising approach to the identification of functional variants that underlie susceptibility to complex diseases. In the present study, the linkage dis
Autor:
V. N. Kharkov, M. G. Spiridonova, Vadim Stepanov, V. P. Puzyrev, N. R. Maksimova, O. F. Medvedeva, A. N. Nogovitsina
Publikováno v:
Molecular Biology. 42:198-208
Gene pool structure of Sakha Republic (Yakutia) native population has been studied: we defined composition and frequencies of Y-chromosome haplogroups for Yakuts. Six haplogroups: C3 x M77, C3c, N*, N2, N3a and R1a1 have been revealed in Yakut gene p
Publikováno v:
Molecular Biology. 41:894-900
The multidrug resistance gene MDR1 (ABCB1) codes for a P-glycoprotein that acts as an ATP-dependent transporter and is involved in removing drugs, xenobiotics, and peptides from the cell. MDR1 is expressed in the brain, kidneys, liver, and gastrointe
Autor:
V. P. Puzyrev, Vadim Stepanov, V. N. Tadinova, V. N. Kharkov, O. F. Medvedeva, M. G. Spiridonova, Mikhail I. Voevoda
Publikováno v:
Russian Journal of Genetics. 43:551-562
Y-chromosomal haplogroups composition and frequencies were analyzed in Northern and Southern Altaians. In the gene pool of Altaians a total of 18 Y-chromosomal haplogroups were identified, including C3xM77, C3c, DxM15, E, F*, J2, I1a, I1b, K*, N*, N2
Autor:
Vadim Stepanov, V. A. Khar’kov, A. V. Marussin, J. R. Pel’s, M. G. Spiridonova, V. P. Puzyrev
Publikováno v:
Russian Journal of Genetics. 43:323-329
The allele and genotype distribution of two alcohol dehydrogenase genes ADH1B (exon 3 polymor- phism A/G ( 47His )), ADH7 (intron 5 polymorphism G/C ) and cytochrome P450 2E1 gene ( CYP2E1 ; 5'-flank- ing region G/C and intron 6 T/A polymorphisms) we
Publikováno v:
Molecular Biology. 38:524-529
Three Russian populations of Siberia were examined for allele and genotype frequency distributions of two alcohol dehydrogenase genes, ADH1B (exon 3 polymorphism A/G detectable with MslI) and ADH7 (intron 5 polymorphism G/C detectable with StyI). No
Publikováno v:
Russian Journal of Genetics. 39:1168-1174
The paper presents the results of analysis of the gene pools of several North Eurasian ethnic groups (Buryats, Evenks, Altaians, Russians, Kyrgyzes, Tuvinians, Tatars, and Ukrainians) examined using a panel of autosomal microsatellite markers (D4S397
Autor:
N. R. Maksimova, M. G. Spiridonova, Nogovitsyna An, I. Yu. Khitrinskaya, V. P. Puzyrev, Vadim Stepanov, Puzyrev Kv
Publikováno v:
Molecular Biology. 37:205-209
The autosomal gene pool of Yakuts was analyzed with a panel of polymorphic Alu insertions. The observed allele frequencies were typical for other Asian ethnic groups. Genetic differentiation of three Yakut populations was relatively high, 2%. East Si