Zobrazeno 1 - 10
of 201
pro vyhledávání: '"M G Nicholls"'
Autor:
M. Pöyhönen-Alho, Risto Kaaja, Matti Viitasalo, Heikki Väänänen, M. G. Nicholls, B.-M. Lindström
Publikováno v:
Diabetic Medicine. 27:988-994
Diabet. Med. 27, 988–994 (2010) Abstract Aims Autonomic nervous system dysfunction is observed in Type 2 diabetes. As gestational diabetes is a potent risk factor of later Type 2 diabetes, we set out to determine whether autonomic nervous system im
Autor:
P. Reilly, N. L. Gilchrist, P. Maguire, M G Nicholls, R. March, Chris Frampton, Karen E. Marshall, A. Heard, R. H. Acland
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 92:1385-1390
Patients who sustain an acute spinal cord injury (SCI) experience rapid dramatic reductions in bone mineral density (BMD), especially marked in sublesional areas and sometimes leading to hypercalcemia and hypercalciuria, as well as increased fracture
Autor:
C H Strey, Russell S. Scott, Arthur Mark Richards, J H Lainchbury, Joanna M. Young, M G Nicholls, Chris Frampton
Publikováno v:
Heart. 92:1603-1609
To investigate the effect of short-term statin treatment on impaired endothelium-dependent vasodilatation and haemodynamic abnormalities typically occurring in chronic heart failure (CHF).In a double-blind, crossover study endothelium-dependent vasod
Autor:
Timothy C. R. Prickett, Timothy G. Yandle, Steve Fisher, Chris Frampton, Vicky A. Cameron, Javed Y. Pathan, M G Nicholls, Enyioma N. Obineche
Publikováno v:
Kidney International. 69(1):152-156
Plasma levels of B-type natriuretic peptide (BNP) and its N-terminal propeptide (NT-BNP) are elevated in renal impairment and provide a robust prognostic index. The effect of peritoneal dialysis on plasma NT-BNP, however, is unknown. Furthermore, no
Publikováno v:
Future Cardiology. 1:235-243
Adrenomedullin (AM) may play a role in the pathophysiology of heart failure. Plasma levels of AM are raised in cardiovascular disease in proportion to severity of cardiac dysfunction, and plasma AM levels measured in acute myocardial infarction and h
Publikováno v:
Journal of Human Hypertension. 19:267-275
Hypertension has been the single most important risk factor for heart failure until the last few decades. Now, it is frequently claimed that atherosclerotic coronary artery disease dominates as the major underlying cause, and hypertension is of lesse
Autor:
M G Nicholls, Richard W. Troughton, Timothy G. Yandle, Lynley K. Lewis, A. M. Richards, John G. Lainchbury
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:1016-1020
The actions of adrenomedullin (ADM), a 52-amino acid peptide, are not well defined in man. We, therefore, studied eight normal volunteers aged 1832 yr in a placebo-controlled crossover study. On the 2 study days, subjects received, in random order, A
Autor:
E. A. Espiner, M G Nicholls, J. G. Turner, John G. Lainchbury, R C Buttimore, John Elliott, David Smyth, A. M. Richards, Timothy G. Yandle, Chris Frampton, Ian Crozier, Hamid Ikram
Publikováno v:
Heart. 81:114-120
Objective—To determine the relations of plasma levels of brain natriuretic peptide (BNP), atrial natriuretic factor (ANF), N-terminal ANF (N-ANF), cyclic guanosine monophosphate (cGMP; the cardiac peptide second messenger), and plasma catecholamine
Autor:
Miriam T. Rademaker, A. M. Richards, Kelvin L. Lynn, Ross R. Bailey, G. B. Pidgeon, M G Nicholls, Timothy G. Yandle, Lynley K. Lewis, Christopher J. Charles
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 24:807-813
1. It has been claimed that ouabain is an endogenous hormone that may be pivotal in the pathogenesis of some forms of hypertension and may exaggerate natriuresis in situations characterized by volume overload. We compared the haemodynamic, renal and
Autor:
John G. Lainchbury, A. M. Richards, N.-Y. Jiang, M G Nicholls, Garth J. S. Cooper, Timothy G. Yandle, Lynley K. Lewis, David H. Coy
Publikováno v:
Clinical Science. 92:467-472
1. Adrenomedullin, a recently discovered 52-amino-acid peptide hormone, circulates in plasma at low picomolar levels in man. Animal studies and studies in vitro indicate that it has diverse biological actions, including vasodilatation, natriuresis an