Zobrazeno 1 - 10
of 29
pro vyhledávání: '"M G Collis"'
Autor:
M G Collis, Christopher J. Bowmer, Mohammad Reza Panjehshahin, Tim S. Munsey, Michael S. Yates
Publikováno v:
Journal of Pharmacy and Pharmacology. 44:109-113
In the rat, treatment with the alkylxanthine 8-cyclopentyl-1,3-dipropylxanthine (CPX) at a dose of 0·1 mg kg−1 antagonizes adenosine-induced falls in renal blood flow and reduces the severity of glycerol-induced acute renal failure. Treatment of g
Publikováno v:
British Journal of Pharmacology. 104:1062-1068
1. The effect of the selective adenosine A1-receptor antagonist, 8-cyclopentyl-1,3-dipropylxanthine (CPX), on the development of cisplatin-induced acute renal failure was investigated in the rat. 2. CPX at doses of 0.03, 0.1 and 0.3 mg kg-1, i.v. cau
Publikováno v:
Journal of Pharmacy and Pharmacology. 43:525-528
The effect of the selective A1-adenosine receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine (CPX, 0·1 mg kg−1 i.v.) administered twice daily to rats has been assessed on the development of renal dysfunction induced by four daily injections of
Publikováno v:
The Journal of Physiology. 427:19-29
1. A number of metabolites have been proposed to control the vascular tone of skeletal muscle during exercise. The present study was designed to investigate the role of adenosine in this response by determining the effect of the adenosine receptor an
Autor:
M. G. Collis
Publikováno v:
Purines in Cellular Signaling ISBN: 9781461279969
Adenosine mediates many of its effects via cell surface receptors. These receptors have been divided into A1 and A2 sub-types, based on the original observation by Van Calker et al (1979) that adenosine could either inhibit or stimulate adenylate cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c35a673c048c6cbe542cda62e409b3d
https://doi.org/10.1007/978-1-4612-3400-5_7
https://doi.org/10.1007/978-1-4612-3400-5_7
Publikováno v:
Journal of Pharmacy and Pharmacology. 43:138-139
We have previously shown that 8-phenyltheophylline (8-PT), a non-selective antagonist at adenosine A1-and A2-receptors, has a diuretic effect. In this study, the diuretic and adenosine antagonist effects of the A1-receptor selective compound 1,3-dipr
Publikováno v:
British Journal of Pharmacology. 98:1066-1074
1. Previous studies have shown that 8-phenyltheophylline (8-PT), a non-selective antagonist at adenosine A1- and A2-receptors, can ameliorate the severity of glycerol-induced acute renal failure (ARF) in the rat. In the present study we have examined
Autor:
M. G. Collis, B. J. Alps
Publikováno v:
Cardiovascular Research. 10:232-235
Exogenous angiotensin II causes noradrenaline supersensitivity in rat mesenteric vasculature preparations. The noradrenaline supersensitivity of tissues from renal/salt hypertensive rats, with low plasma renin activity, is not caused by endogenous an
Publikováno v:
Hypertension. 2:45-52
The renal resistance vessels of the mature spontaneously hypertensive rat (SHR) exhibit increased reactivity to vasoconstrictor agonists. This could be a cause or consequence of hypertension. We have compared vascular reactivity in isolated perfused
Autor:
B J Alps, M G Collis
Publikováno v:
Journal of Pharmacy and Pharmacology. 25:621-628
The perfused mesenteric vasculature of the rat is a specific, sensitive and stable preparation for the rapid determination of α-adrenoceptor blocking pA2 values. Both types of pA2 determination—the direct determination (Schild, 1947) and the Arunl