Induction of Cure in Early Arthritis (I CEA): study protocol for an investigator-initiated randomized single-blind clinical trial with open-label extension to compare three treatment strategies in patients with newly diagnosed undifferentiated arthritis

Autor: S. A. Bergstra, L. van Ouwerkerk, I. S. Nevins, J. A. van der Pol, G. S. Helmich, I. Hest, A. van Veen, R. Bos, Y. P. M. Goekoop-Ruiterman, H. E. Vonkeman, J. Bijsterbosch, P. H. P. de Jong, M. Güler-Yüksel, S. Böhringer, T. W. J. Huizinga, F. A. van Gaalen

Publikováno v: Trials, Vol 25, Iss 1, Pp 1-15 (2024)

Abstract Background Undifferentiated arthritis (UA) is a term used to describe patients with inflammatory arthritis that has not differentiated into a specific rheumatic disease. UA may be a pre-stage of rheumatoid arthritis (RA) or another inflammat

Externí odkaz: https://doaj.org/article/f87499fd47d949ffb7a08bf248230bbf

POS0529 LONG-TERM LOCAL JOINT DAMAGE PROGRESSION IN RHEUMATOID ARTHRITIS IS RELATED TO CUMULATIVE LOCAL CLINICAL JOINT INFLAMMATION

Autor: S. Heckert, S. A. Bergstra, Y. Goekoop-Ruiterman, M. Güler-Yüksel, W. Lems, M. Van Oosterhout, T. Huizinga, C. Allaart

Publikováno v: Annals of the Rheumatic Diseases. 81:525.2-525

BackgroundPreviously we showed that joint inflammation in rheumatoid arthritis (RA) tends to recur in the same joint, suggesting local factors contributing to joint inflammation. In the same study population, we now investigated whether cumulative lo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5552c7a46312f8873e7eb43ec10131f5
https://doi.org/10.1136/annrheumdis-2022-eular.1628

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Can bone loss in rheumatoid arthritis be prevented?

Autor: Willem F. Lems, M Güler-Yüksel, Marijn Vis

Publikováno v: Osteoporosis International, 24(10), 2541-2553. Springer London
Vis, M, Guler-Yuksel, M & Lems, W F 2013, ' Can bone loss in rheumatoid arthritis be prevented? ', Osteoporosis International, vol. 24, no. 10, pp. 2541-2553 . https://doi.org/10.1007/s00198-013-2334-5

Rheumatoid arthritis (RA) is a systemic inflammatory disease that can lead to local joint deformations (bone erosions and joint space narrowing) and to extra-articular phenomena, including generalized osteoporosis. In addition, in patients with RA, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa8b293790a4e4c2841bf0ee902bf9d
https://doi.org/10.1007/s00198-013-2334-5

The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study

Autor: P E H Seys, H. Karel Ronday, N.B. Klarenbeek, K. Huub Han, M Güler-Yüksel, Cornelia F Allaart, Tom W J Huizinga, Ben A. C. Dijkmans, Sjoerd M van der Kooij, Pit J S M Kerstens

Publikováno v: Annals of the Rheumatic Diseases, 70(6), 1039-1046. BMJ Publishing Group
Annals of the Rheumatic Diseases, 70(6), 1039-1046
Klarenbeek, N B, Guler-Yuksel, M, van der Kooij, S M, Han, K H, Ronday, H K, Kerstens, P J S M, Seys, P E H, Huizinga, T W J, Dijkmans, B A C & Allaart, C F 2011, ' The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study ', Annals of the Rheumatic Diseases, vol. 70, no. 6, pp. 1039-1046 . https://doi.org/10.1136/ard.2010.141234

ObjectiveTo compare clinical and radiological outcomes of four dynamic treatment strategies in recent-onset rheumatoid arthritis (RA) after 5 years follow-up.Methods508 patients with recent-onset RA were randomly assigned into four treatment strategi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ab24ebe5591f70a53aa46c5624f3e7
https://doi.org/10.1136/ard.2010.141234