Zobrazeno 1 - 10
of 19
pro vyhledávání: '"M G, Shagoian"'
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 59(5)
Zofran is a selective antagonist of 5-HT3 receptors which effectively prevents postradiation dyspeptic and behavioral disorders in dogs and rats. Administration of the drug normalizes intestinal absorption and propulsion activity in irradiated animal
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 35(2)
In the experiments with rats and dogs it was shown that irradiation within the dose range of 50-100 Gy is accompanied by the increasing of enkephaline content in various brain structures and beta-endorphine level in blood plasma. The blocking of the
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 34(1)
In experiments with dogs and rats it has been shown that early after high doses of irradiation, the content of prostaglandins in the blood plasma increases, whereas in the intestinal tissues it decreases. The inhibitors of prostaglandins synthesis in
Autor:
V I, Legeza, M G, Shagoian, I V, Markovskaia, T P, Vasil'eva, T D, Pozharisskaia, I I, Alekseeva, O I, Lokteva
Publikováno v:
Radiobiologiia. 30(5)
In experiments with rats exposed to 200 Gy radiation it was shown that the diarrhea effect of serotonin under the effect of radiation is implemented via D- and M-type receptors, and that of histamine via H1 and H2 receptors. Serotonin and histamine,
Publikováno v:
Farmakologiia i toksikologiia. 49(4)
Dimetpramide, a new antiemetic drug (manufactured in the USSR) from the group of substituted benzamides, produced, due to blockade of catecholaminergic receptors, an increase in dopamine and noradrenaline turnover rates in the subcortical-brainstem r
Publikováno v:
Terapevticheskii arkhiv. 60(11)
Publikováno v:
Voprosy onkologii. 33(9)
Publikováno v:
Radiobiologiia. 26(2)
In experiments on rats it was shown that after 20 Gy irradiation dopamine and homovanilic acid content increases in the caudate nucleus and limbic structures of the forebrain: dopamine disappears more readily when its biosynthesis is blocked. The rat
Publikováno v:
Farmakologiia i toksikologiia. 48(6)
A new original drug dimetpramid injected per os into mice and rats exhibits moderate toxicity, exerts a weak irritating action on the mucous membranes. The drug is capable of penetrating via the unaffected skin, producing systemic effects. With all r
Publikováno v:
Farmakologiia i toksikologiia. 48(1)
It has been demonstrated that dimethpramide exerted an adverse effect on the sexual glands of female rats. It provoked an inhibition of ovarian function (derangement of cycling rhythmicity, the loss of individual cycle stages) and depletion of energy