Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M G, Muto"'
Autor:
Harvey J. Mamon, William K. Dahlberg, Edouard I. Azzam, M G Muto, Hatsumi Nagasawa, John B. Little
Publikováno v:
International journal of radiation biology. 79(10)
The ataxia-telangiectasia mutated (ATM) gene encodes a protein kinase, the activation of which is an early event in the cellular response to ionizing radiation. One of the many substrates of ATM is BRCA1 (breast cancer 1, early onset gene), which has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b91f3e87af4c02de9f0a085b1ed578e
https://pubmed.ncbi.nlm.nih.gov/14630541
https://pubmed.ncbi.nlm.nih.gov/14630541
Autor:
B H, Ortiz, M, Ailawadi, C, Colitti, M G, Muto, M, Deavers, E G, Silva, R S, Berkowitz, S C, Mok, D M, Gershenson
Publikováno v:
Cancer research. 61(19)
The role of serous borderline ovarian tumors (BOTs) in the pathogenesis of serous ovarian carcinomas is unclear. Some authors have compared mutations in serous BOTs to those in serous ovarian carcinomas, but the data on two common oncogenes, p53 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2826331d5c17cbb92aa317c47694837b
https://pubmed.ncbi.nlm.nih.gov/11585764
https://pubmed.ncbi.nlm.nih.gov/11585764
Autor:
J O, Schorge, M G, Muto, S J, Lee, L W, Huang, W R, Welch, D A, Bell, E Z, Keung, R S, Berkowitz, S C, Mok
Publikováno v:
Cancer research. 60(5)
Papillary serous carcinoma of the peritoneum (PSCP) is believed to develop de novo from the peritoneal lining of the pelvis and abdomen. Although it is histologically indistinguishable from serous ovarian carcinoma, PSCP exhibits minimal or absent ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6faadba33a8e158a4629ee76db1d53d2
https://pubmed.ncbi.nlm.nih.gov/10728699
https://pubmed.ncbi.nlm.nih.gov/10728699
Publikováno v:
Obstetrics and gynecology. 92(4 Pt 1)
To compare BRCA1 mutations in papillary serous carcinoma of the peritoneum and papillary serous ovarian carcinoma.Germline DNA from 17 consecutive patients with peritoneal carcinoma was screened for mutations in the BRCA1 gene using single-strand con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae784d12106527ae9f5f32d23beeced7
https://pubmed.ncbi.nlm.nih.gov/9764635
https://pubmed.ncbi.nlm.nih.gov/9764635
Publikováno v:
Cancer research. 56(11)
To further define the genetic events that could lead to the development of borderline ovarian tumors (BOTs), we analyzed 13 microsatellite markers on chromosomes 3p and q in 18 BOTs and compared the results to 31 serous invasive epithelia] ovarian ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ee7b3c85071afc7cfe0901e3e7da57e
https://pubmed.ncbi.nlm.nih.gov/8653685
https://pubmed.ncbi.nlm.nih.gov/8653685
Publikováno v:
Oncogene. 12(10)
Polymerase chain reaction (PCR) analysis of microsatellite polymorphisms corresponding to four loci which map to chromosome 17p and 11 loci which map to chromosome 17q was performed to screen for loss of heterozygosity (LOH) in paired normal and tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88a8eafe169ab57d13fc7e5d7e448773
https://pubmed.ncbi.nlm.nih.gov/8668340
https://pubmed.ncbi.nlm.nih.gov/8668340
Publikováno v:
Cancer research. 56(6)
Among women of Ashkenazi Jewish origin, a frameshift mutation of the BRCA1 gene, designated 185delAG, occurs with a carrier frequency of approximately 1% and is estimated to account for about 39% of ovarian cancer cases occurring prior to age 50 year
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25f6224649c836b7025bf1d84c68a173
https://pubmed.ncbi.nlm.nih.gov/8640808
https://pubmed.ncbi.nlm.nih.gov/8640808
Publikováno v:
Oncogene. 12(4)
Allelic deletions on chromosome 17q21 in sporadic ovarian cancer are common, suggesting that inactivation of a tumor suppressor gene(s) in that region may be important for the etiology of these tumors. The recently identified BRCA1 gene on 17q21, inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f092fa5f72cb308fcadb6d0de3ab70a
https://pubmed.ncbi.nlm.nih.gov/8632895
https://pubmed.ncbi.nlm.nih.gov/8632895
Autor:
M G, Muto, A I, Kassis
Publikováno v:
Cancer. 76
Conventional therapy for epithelial ovarian cancer, including aggressive cytoreductive surgery followed by combination chemotherapy regimens, has failed to reduce the number of deaths caused by this disease, which remains the most lethal of gynecolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::772241a96e9dba8ce529344ff8dd5f70
https://pubmed.ncbi.nlm.nih.gov/8634994
https://pubmed.ncbi.nlm.nih.gov/8634994
Autor:
M G, Muto, W R, Welch, S C, Mok, C A, Bandera, P M, Fishbaugh, S W, Tsao, C C, Lau, H M, Goodman, R C, Knapp, R S, Berkowitz
Publikováno v:
Cancer research. 55(3)
Histopathological evidence suggests that papillary serous carcinoma of the peritoneum (PSCP) may be multifocal in origin. Utilizing a PCR based method to detect tandem repeat polymorphisms in formalin fixed tissue, loss of heterozygosity at eight loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e78dca43cba0bfa15efbc02822768f4
https://pubmed.ncbi.nlm.nih.gov/7834614
https://pubmed.ncbi.nlm.nih.gov/7834614