Zobrazeno 1 - 6 of 6 pro vyhledávání: '"M G, McMenamin"'
1
Alterations of p14ARF, p53, and p73 genes involved in the E2F-1-mediated apoptotic pathways in non-small cell lung carcinoma
Autor: S A, Nicholson, N T, Okby, M A, Khan, J A, Welsh, M G, McMenamin, W D, Travis, J R, Jett, H D, Tazelaar, V, Trastek, P C, Pairolero, P G, Corn, J G, Herman, L A, Liotta, N E, Caporaso, C C, Harris
Publikováno v: Cancer research. 61(14)
Overexpression of E2F-1 induces apoptosis by both a p14ARF-p53- and a p73-mediated pathway. p14ARF is the alternate tumor suppressor product of the INK4a/ARF locus that is inactivated frequently in lung carcinogenesis. Because p14ARF stabilizes p53,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::66b0eace4644822090bc57b45a4ba0e1
https://pubmed.ncbi.nlm.nih.gov/11454718
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2
Chlorozotocin, 2-(3-(2-chloroethyl)-3-nitrosoureido)-D-glucopyranose, an antitumor agent with modified bone marrow toxicity
Autor: T, Anderson, M G, McMenamin, P S, Schein
Publikováno v: Cancer research. 35(3)
Chlorozotocin, 2-(3-(2-chloroethyl)-3-nitrosoureido)-D-glucopyranose, is a newly synthesized, water-soluble nitrosourea antitumor agent that is active against L1210 leukemia in mice. A 701% and a 401% increase in life-span were attained with a dose t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eea8471ac94881816a271ac0864e1d60
https://pubmed.ncbi.nlm.nih.gov/123170
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3
The relationship between the catalytic activities of rabbit pulmonary cytochrome P-450 isozymes and the lung-specific toxicity of the furan derivative, 4-ipomeanol
Autor: C R, Wolf, C N, Statham, M G, McMenamin, J R, Bend, M R, Boyd, R M, Philpot
Publikováno v: Molecular pharmacology. 22(3)
Metabolism of the pulmonary toxin, 4-ipomeanol, in microsomal preparations from rabbit liver and lung and in purified cytochrome P-450-dependent monooxygenase systems was investigated. The rate of formation of reactive electrophilic products from 4-i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fd206cdd462e5fd18e9198d76663a309
https://pubmed.ncbi.nlm.nih.gov/7155130
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4
Metabolism of arachidonic acid in human lung cancer cell lines
Autor: S S, Lau, J B, McMahon, M G, McMenamin, H M, Schuller, M R, Boyd
Publikováno v: Cancer research. 47(14)
The metabolism of arachidonic acid (AA) was studied in two pulmonary bronchioloalveolar-carcinoma cell lines (NCI-H322 and NCI-H358) and two small cell lung carcinoma cell lines (NCI-H69 and NCI-H128). Exogenous AA was metabolized only in the NCI-H32
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ceb0e71f4abfc8bd7a2dada41e9dab3d
https://pubmed.ncbi.nlm.nih.gov/3036346
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5
Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes
Autor: R R, Reddel, Y, Ke, B I, Gerwin, M G, McMenamin, J F, Lechner, R T, Su, D E, Brash, J B, Park, J S, Rhim, C C, Harris
Publikováno v: Cancer research. 48(7)
Normal human bronchial epithelial cells were infected with SV40 virus or an adenovirus 12-SV40 hybrid virus, or transfected via strontium phosphate coprecipitation with plasmids containing the SV40 early region genes. Colonies of morphologically alte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9cfc4baebe4276e2e84f5d2b6450614e
https://pubmed.ncbi.nlm.nih.gov/2450641
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