Zobrazeno 1 - 10
of 21
pro vyhledávání: '"M G, Knize"'
Publikováno v:
Journal of Heterocyclic Chemistry. 45:1641-1649
Synthesis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), three structural isomers, and two desphenyl PhIP congeners has been carried out. Mutagenic potency was evaluated using S. typhimurium strain TA98 in the Ames test. Mutagenic potency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d5fedcbacf2c738b75a320916e9abdb
https://doi.org/10.1002/jhet.5570450614
https://doi.org/10.1002/jhet.5570450614
Publikováno v:
ChemInform. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::543f30af26a9c29dfc25d22c7a7a1719
https://doi.org/10.1002/chin.200915154
https://doi.org/10.1002/chin.200915154
Autor:
C G Bailey, M G Knize
A limitation in the mass spectrometry of biological materials is the reduced ion formation caused by sample complexity. We proposed to develop an enabling technology, single cell planar chromatography, which will greatly increase the amount of chemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff25021122181b6b4eed0b802c50259
https://doi.org/10.2172/902253
https://doi.org/10.2172/902253
Autor:
G A, Keating, R, Sinha, D, Layton, C P, Salmon, M G, Knize, K T, Bogen, C F, Lynch, M, Alavanj
Publikováno v:
Cancer causescontrol : CCC. 11(8)
To compare indicators of heterocyclic amine (HCA) exposure with HCA concentrations in home-cooked meat samples.Pan-fried hamburger and steak samples were obtained from individuals stating a preference for medium, well done and very well done meat. Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bddf4555e0d47b26e0ad0c59fa4bb844
https://pubmed.ncbi.nlm.nih.gov/11065010
https://pubmed.ncbi.nlm.nih.gov/11065010
Publikováno v:
Advances in experimental medicine and biology. 459
Heterocyclic aromatic amines (HAA) and polycyclic aromatic hydrocarbons (PAH) are mutagens and animal carcinogens sometimes formed when foods are heated or processed. Determining their role in cancer etiology depends on comparing human exposures and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a9cbd76cb5f4755a3aeef0f978803b2
https://pubmed.ncbi.nlm.nih.gov/10335376
https://pubmed.ncbi.nlm.nih.gov/10335376
Autor:
R, Sinha, N, Rothman, E D, Brown, C P, Salmon, M G, Knize, C A, Swanson, S C, Rossi, S D, Mark, O A, Levander, J S, Felton
Publikováno v:
Cancer research. 55(20)
Heterocyclic aromatic amines (HAAs) are mutagenic and carcinogenic compounds found in meats cooked at high temperatures. Although chicken is consumed in large quantities in the United States, there is little information on its HAA content. The object
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ba0c9ee72a554df6aa2dbebb9751df2
https://pubmed.ncbi.nlm.nih.gov/7553619
https://pubmed.ncbi.nlm.nih.gov/7553619
Publikováno v:
Princess Takamatsu symposia. 23
The mutagenic activity and the mass amount of heterocyclic amines responsible for the mutagenic activity have been measured in some cooked foods. Cooked meats are the predominant source of mutagenic activity in the diet with values ranging from 0 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::879e08c99d9acee0ff61a33acd84a829
https://pubmed.ncbi.nlm.nih.gov/8844793
https://pubmed.ncbi.nlm.nih.gov/8844793
Publikováno v:
Princess Takamatsu symposia. 23
Cooking, heat processing, and pyrolysis of protein-rich foods induce the formation of structurally related heterocyclic aromatic amines that have been found to be mutagenic in bacteria, mammalian cells in culture and mice. All these compounds are pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09da1e98445ae8c516fac5fc2475a82c
https://pubmed.ncbi.nlm.nih.gov/8844795
https://pubmed.ncbi.nlm.nih.gov/8844795
Autor:
R, Sinha, N, Rothman, E D, Brown, S D, Mark, R N, Hoover, N E, Caporaso, O A, Levander, M G, Knize, N P, Lang, F F, Kadlubar
Publikováno v:
Cancer research. 54(23)
Heterocyclic aromatic amines (HAAs) are formed when meat juices are pyrolyzed. In humans HAAs are activated in vivo by cytochrome P4501A2 (CYP1A2) and N-acetyltransferase (NAT2) to mutagens or carcinogens. While activity of NAT2 is noninducible, expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a19cadd9f85bc752227356288a009e9
https://pubmed.ncbi.nlm.nih.gov/7954461
https://pubmed.ncbi.nlm.nih.gov/7954461