Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M G, Jannuzzo"'
Autor:
Elio M. Vinci, Armando Santoro, Giordano Vitali, Mariangela Mariani, Rossana Berardi, Scott T. Tagawa, Hielke J. Meulenbeld, Ronald de Wit, Luigi Dogliotti, Jean P. Bleuse, Cora N. Sternberg, Federico Cappuzzo, Eric Raymond, Anna Petroccione, M. G. Jannuzzo
Publikováno v:
BJU International. 111:44-52
What's known on the subject? and What does the study add? Since their discovery aurora kinases have been identified as a potential target in anticancer therapy and currently many aurora-selective small molecule kinase inhibitors are in development. A
Autor:
M. Schena, S. Crippa, A. Petroccione, S. Comis, Carlo Barone, Steven D. Weitman, R. MacArthur, Marco Merlano, G. Fornari, F. Fiorentini, Domenica Lorusso, M. G. Jannuzzo, Mario Airoldi, F. Caponigro
Publikováno v:
Cancer Chemotherapy and Pharmacology. 66:389-394
Brostallicin is a DNA minor groove binder which shows enhanced antitumor activity in cells which are resistant to several anticancer agents due to their high glutathione S-transferase (GST)/glutathione content. Phase I and II clinical trials of singl
Autor:
M. G. Jannuzzo, Jean-Pierre Delord, Patrick Schöffski, Giovanni Scambia, Anna Petroccione, C. Davite, Thomas Gauler, M.J.A. de Jonge, Armando Santoro, Benjamin Besse
Publikováno v:
Annals of Oncology, 26(3), 598-607. Elsevier Ltd.
According to the results of this multi-tumour, multi-institutional Simon two-stage design phase II study the aurora kinase inhibitor danusertib was found to have only limited anti-tumour activity in heavily pre-treated patients with breast, ovarian,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff3f37b1378f2e404fa1c3c2eee7688
https://lirias.kuleuven.be/handle/123456789/490090
https://lirias.kuleuven.be/handle/123456789/490090
Autor:
P. Duchene, M. G. Jannuzzo, J. P. Laneury, Georges Houin, J. C. Fleishaker, P. Rampal, A. Tran
Publikováno v:
Clinical Drug Investigation. 19:473-477
Objective: Reboxetine is a unique selective norepinephrine (noradrenaline) reuptake inhibitor (selective NRI) that is effective and well tolerated at a dosage of 8 to 10 mg/day in the short- and long-term treatment of depression. The objective of the
Publikováno v:
Biopharmaceuticsdrug disposition. 20(4)
Reboxetine is a racemic mixture of FCE 22071 and FCE 21684 enantiomers. The pharmacokinetics of the enantiomers of reboxetine were observed to be linear in male healthy subjects (n = 6) after the administration of 1.5, 3, 4.5 mg dose of reboxetine as
Autor:
Mario Airoldi, Giovanni Scambia, D. Lorusso, G. Fornari, M. Schena, M. Quirino, Marco Merlano, S. Crippa, M. G. Jannuzzo, F. Caponigro
Publikováno v:
European Journal of Cancer Supplements. 5:111-112
Autor:
Armando Santoro, M. G. Jannuzzo, Cristina Davite, Silvia Novello, Ahmad Awada, Jean-Pierre Delord, Wilfried Eberhardt, Maja J.A. de Jonge, Maurizio Nicodemo, Thomas Gauler, Paolo Marchetti, Anna Petroccione, Mariangela Mariani, Pierfranco Conte, Benjamin Besse, Egbert F. Smit, Roberta Ceruti, Carlo Barone, Elizabeth Ruth Plummer
Publikováno v:
Publons
ResearcherID
ResearcherID
e19138 Background: D is an ATP competitive pan-aurora kinases inhibitor with activity also against FGFRs, VEGFR, Ret, TrkA, Scr, and Abl. Methods: Eligible pts had NSCLC progressing for advanced/metastatic disease after 1 prior chemotherapy line (CT)
Autor:
G. Vitali, Hielke J. Meulenbeld, E. M. Vinci, M. G. Jannuzzo, Eric Raymond, Luigi Dogliotti, Armando Santoro, Cora N. Sternberg, Scott T. Tagawa, Federico Cappuzzo, J. P. Bleuse, R. de Wit, Mariangela Mariani, Anna Petroccione, Rossana Berardi
Publikováno v:
Journal of Clinical Oncology. 29:4628-4628
4628 Background: D is a small molecule that inhibits Aurora kinases, proteins regulating mitosis, implicated in tumorigenesis and overexpressed in prostate cancer. After D administration, tumor reg...
Autor:
M. G. Jannuzzo, Michela Maur, Ignace Vergote, Domenica Lorusso, V. N. Trillet-Lenoir, Jean-Pierre Delord, Anna Petroccione, G. Locatelli, Patrick Schöffski, Elisa Gallerani
Publikováno v:
Journal of Clinical Oncology. 28:5014-5014
5014 Background: D is a small molecule that inhibits a urora kinases, proteins regulating mitosis implicated in tumorigenesis and overexpressed in BC and OC. Methods: In both tumor categories eligi...
Autor:
Emilio Bajetta, M.J.A. de Jonge, E. Endlicher, B. Laffranchi, R. Giuliani, Armando Santoro, C. Barone, A. Hendlisz, R. Spinelli, M. G. Jannuzzo
Publikováno v:
Journal of Clinical Oncology. 28:e13558-e13558
e13558 Background: D is a pan-aurora kinases inhibitor also active against other kinases with oncogenic potential, such as TRKA, RET, FGFRs, ABL. D has been showed to be active against a wide range...