Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M G, Fornaretto"'
Autor:
M. G. Fornaretto, Sergio Mantegani, Carla Caccia, Robert A. McArthur, Gabriele Damiani, Mario Varasi, Enzo Brambilla
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 8:1117-1122
Novel classes of 13- and 14-tertbutyl-ergoline derivatives were prepared, and characterised in vitro for their affinity for adrenergic, dopaminergic and serotonergic binding sites. This study particularly examines the importance of the presence and t
Autor:
Mario Varasi, Carla Caccia, Enzo Brambilla, Luca Baumer, Robert A. McArthur, Sergio Mantegani, M. G. Fornaretto
Publikováno v:
European Journal of Medicinal Chemistry. 33:279-292
The synthesis and the structure-affinity relationship (S.A.F.I.R.) study for the 5-HT 1A receptor sites of a novel series of 5(10→9) abeo -ergoline derivatives are presented. Most derivatives showed moderate to high affinity and selectivity for 5-H
Autor:
Mario Varasi, Enzo Brambilla, M. G. Fornaretto, R. A. Mc Arthur, Sergio Mantegani, Carla Caccia
Publikováno v:
European Journal of Medicinal Chemistry. 32:795-804
Summary A series of novel 13-tert-butyl-ergoline derivatives was prepared and evaluated for affinity to adrenergic, dopaminergic and serotonergic receptor sites. Selectivity for 5-HT1A receptors versus α1, α2, D1, D2, and 5-HT2 appears to be influe
Autor:
F. Berardi, Carla Caccia, Robert A. McArthur, M. G. Fornaretto, Marcello Leopoldo, R. Perrone, Vincenzo Tortorella
Publikováno v:
ChemInform. 27
Autor:
Nicola Carfagna, M. G. Fornaretto, Monica Colombo, Enzo Brambilla, Mario Varasi, Carla Caccia, Sergio Mantegani, Paolo Cremonesi, Robert A. McArthur
Publikováno v:
ChemInform. 28
A class of (E) and (Z)-3-styrylpiperidine derivatives was prepared as racemates and evaluated for affinity at σ binding sites labeled with [ 3 H]-(+)-SKF-10,047. Some of these compounds exhibited high affinity and selectivity for σ versus D 1 and D
Autor:
F. Berardi, Robert A. McArthur, Vincenzo Tortorella, Carla Caccia, M. G. Fornaretto, R. Perrone, Nicola Antonio Colabufo
Publikováno v:
ChemInform. 28
Autor:
Sergio Mantegani, Enzo Brambilla, M. G. Fornaretto, Mario Varasi, R. A. Mc Arthur, Carla Caccia
Publikováno v:
ChemInform. 29
Summary A series of novel 13-tert-butyl-ergoline derivatives was prepared and evaluated for affinity to adrenergic, dopaminergic and serotonergic receptor sites. Selectivity for 5-HT1A receptors versus α1, α2, D1, D2, and 5-HT2 appears to be influe
Autor:
Gabriele Damiani, Enzo Brambilla, Carla Caccia, Sergio Mantegani, Mario Varasi, Robert A. McArthur, M. G. Fornaretto
Publikováno v:
ChemInform. 29
Novel classes of 13- and 14-tertbutyl-ergoline derivatives were prepared, and characterised in vitro for their affinity for adrenergic, dopaminergic and serotonergic binding sites. This study particularly examines the importance of the presence and t
Autor:
Sergio Mantegani, Mario Varasi, Robert A. McArthur, Luca Baumer, Enzo Brambilla, M. G. Fornaretto, Carla Caccia
Publikováno v:
ChemInform. 29
The synthesis and the structure-affinity relationship (S.A.F.I.R.) study for the 5-HT 1A receptor sites of a novel series of 5(10→9) abeo -ergoline derivatives are presented. Most derivatives showed moderate to high affinity and selectivity for 5-H
Autor:
N, Carfagna, C, Caccia, S, Mantegani, S, Cavanus, M G, Fornaretto, M, Buonamici, A C, Rossi, R, Roncucci, R G, Fariello
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 259(1)
The effects of FCE 23884 [4-(9,10-didehydro-6-methylergolin-8 beta-yl) methyl-piperazine-2,6-dione] were examined using a variety of biochemical methods. In vitro assays showed that FCE 23884 bound to D-2, alpha-2 and 5-hydroxytryptamine1A sites with