Zobrazeno 1 - 10
of 28
pro vyhledávání: '"M G, Federici"'
Publikováno v:
Cancer. 89(2)
The high mortality associated with ovarian carcinoma is largely a reflection of the inability to diagnose the disease at an early stage; the identification of a histologic lesion or molecular marker associated early stages of transformation would rep
Autor:
J, Boyd, Y, Sonoda, M G, Federici, F, Bogomolniy, E, Rhei, D L, Maresco, P E, Saigo, L A, Almadrones, R R, Barakat, C L, Brown, D S, Chi, J P, Curtin, E A, Poynor, W J, Hoskins
Publikováno v:
JAMA. 283(17)
Most hereditary ovarian cancers are associated with germline mutations in BRCA1 or BRCA2. Attempts to define the clinical significance of BRCA mutation status in ovarian cancer have produced conflicting results, especially regarding survival.To deter
Publikováno v:
Cancer research. 59(2)
Genetic instability of microsatellite repeat sequences [microsatellite instability (MI)] is commonly seen in tumors associated with the hereditary nonpolyposis colorectal cancer syndrome and is a result of inactivating mutations in any of several gen
Autor:
E, Rhei, F, Bogomolniy, M G, Federici, D L, Maresco, K, Offit, M E, Robson, P E, Saigo, J, Boyd
Publikováno v:
Cancer research. 58(15)
Hereditary ovarian cancers associated with germline mutations in either BRCA1 or BRCA2 were studied to determine whether somatic mutation of the P53 gene is required for BRCA-linked ovarian tumorigenesis and further, whether the spectrum of additiona
Publikováno v:
Cancer research. 57(17)
A novel gene was identified recently at chromosome 10q23, named PTEN or MMAC1, and based on several criteria it was designated as a potential human tumor suppressor gene. Loss of heterozygosity affecting this region of 10q is observed in several canc
Autor:
C L, Finstad, K O, Lloyd, M G, Federici, C, Divgi, E, Venkatraman, R R, Barakat, R D, Finn, S M, Larson, W J, Hoskins, J L, Humm
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(8)
Our objective was to quantify the targeting of the monoclonal antibody (mAb) MX35 F(ab')2 to micrometastatic epithelial ovarian cancer. This mAb detects a Mr 95,000 glycoprotein with homogeneous distribution on 80% of ovarian tumor specimens. Six pat
Publikováno v:
Cancer. 73(7)
Interleukin-6 (IL-6) is a multifunctional cytokine that can be produced by human ovarian cancer cells. Elevated IL-6 levels have been found in the serum and ascites of patients with ovarian cancer, but its role in this disease has not been clearly es
Publikováno v:
Cancer. 73(5)
Although expression of the HER-2/neu oncogene may be of some prognostic importance in advanced ovarian cancer, its role in early-stage disease has not been established. The current study examined the prevalence and significance of HER-2/neu expressio
Autor:
Mucha, Eike1,2, Lettow, Maike1,2, Marianski, Mateusz1, Thomas, Daniel A.1, Struwe, Weston B.3, Harvey, David J.4, Meijer, Gerard1, Seeberger, Peter H.5,6, von Helden, Gert1 helden@fhi-berlin.mpg.de, Pagel, Kevin1,2 kevin.pagel@fu-berlin.de
Publikováno v:
Angewandte Chemie. Jun2018, Vol. 130 Issue 25, p7562-7565. 4p.
Autor:
Shakeri, Amid, Jarad, Noor Abu, Terryberry, Jeff, Khan, Shadman, Leung, Ashlyn, Chen, Simeng, Didar, Tohid F.
Publikováno v:
Small; 11/12/2020, Vol. 16 Issue 45, p1-10, 10p