Zobrazeno 1 - 10
of 64
pro vyhledávání: '"M G, Brattain"'
Publikováno v:
Cancer research. 61(16)
The pancreatic cancer cell line, MIA PaCa-2 is not responsive to transforming growth factor beta (TGF-beta) because of a lack of expression of the TGF-beta type II receptor (RII). We show that the lack of RII expression is caused by a deficit of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1bf6bcf7e5ec8ed9354c28cc5e91c0e
https://pubmed.ncbi.nlm.nih.gov/11507078
https://pubmed.ncbi.nlm.nih.gov/11507078
Autor:
S C, Ye, J M, Foster, W, Li, J, Liang, E, Zborowska, S, Venkateswarlu, J, Gong, M G, Brattain, J K, Willson
Publikováno v:
Cancer research. 59(18)
Transforming growth factor betas (TGF-betas) are a growth factor family with negative autocrine growth functions for most epithelial cells including colon carcinoma cell lines. Both type I (RI) and type II (RII) transmembrane TGF-beta receptors have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccbf86232f7040bc4eb3617ae8b66ce7
https://pubmed.ncbi.nlm.nih.gov/10493532
https://pubmed.ncbi.nlm.nih.gov/10493532
Autor:
W M, Grady, L L, Myeroff, S E, Swinler, A, Rajput, S, Thiagalingam, J D, Lutterbaugh, A, Neumann, M G, Brattain, J, Chang, S J, Kim, K W, Kinzler, B, Vogelstein, J K, Willson, S, Markowitz
Publikováno v:
Cancer research. 59(2)
We previously demonstrated that mutational inactivation of transforming growth factor beta type II receptors (RIIs) is very common among the 13% of human colon cancers with microsatellite instability. These mutations principally cluster in the BAT-RI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b60b02d6993322022344690d7132702
https://pubmed.ncbi.nlm.nih.gov/9927040
https://pubmed.ncbi.nlm.nih.gov/9927040
Publikováno v:
Journal of cellular physiology. 177(3)
Previously, we reported that unaggressive, growth factor-dependent FET human colon carcinoma cells downregulated their transforming growth factor alpha (TGFalpha) expression in a quiescent state (G0/G1) induced by growth factor and nutrient deprivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14850fa2eaec81396cf7a2fb9a856bc4
https://pubmed.ncbi.nlm.nih.gov/9808147
https://pubmed.ncbi.nlm.nih.gov/9808147
Autor:
Y, Ko, S S, Banerji, Y, Liu, W, Li, J, Liang, H D, Soule, R J, Pauley, J K, Willson, E, Zborowska, M G, Brattain
Publikováno v:
Journal of cellular physiology. 176(2)
To analyze transforming growth factor-beta (TGF-beta) response during MCF-7 cell progression, early passage (MCF-7E,200 passage) and late passage (MCF-7L,500 passage) cells were compared. MCF-7E cells showed an IC50 of approximately 10 ng/ml of TGF-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62687e9c500f380332f404667293d912
https://pubmed.ncbi.nlm.nih.gov/9648930
https://pubmed.ncbi.nlm.nih.gov/9648930
Publikováno v:
Journal of cellular physiology. 175(2)
Autocrine transforming growth factor alpha (TGFalpha) activity and control mechanisms for its expression were examined in a representative clonal isolate (CBS4) of a well-differentiated human colon carcinoma cell line designated CBS. CBS4 cells expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74d5ea2dfa622c2a7e951fb11aee261f
https://pubmed.ncbi.nlm.nih.gov/9525476
https://pubmed.ncbi.nlm.nih.gov/9525476
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 8(1)
We characterized the expression of alpha 5 beta 1 integrin in two distinct phenotypes of colon carcinoma cell lines. Highly invasive colon cell lines (designated Group I cell lines) expressed higher levels of integrin alpha 5 beta 1 mRNA and protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccf58a02c6ba2b1f85929cd1ba5a1b40
https://pubmed.ncbi.nlm.nih.gov/8993837
https://pubmed.ncbi.nlm.nih.gov/8993837
Publikováno v:
Journal of cellular physiology. 168(3)
We investigated TGF-beta response and the expression of TGF-beta receptors in clones of MOSER colon carcinoma cells (designated MOSER II and MOSER III-10) as a function of their growth state. TGF-beta 1 response as assessed by induction of fibronecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec847ca3fd945b86b3430c62446baeca
https://pubmed.ncbi.nlm.nih.gov/8816926
https://pubmed.ncbi.nlm.nih.gov/8816926
Publikováno v:
Cancer research. 55(10)
Here we describe human colon carcinoma cell clones, isolated from a transforming growth factor beta (TGF-beta)-responsive parental cell line, which display differential sensitivities to TGF-beta 1 and TGF-beta 2 isoforms. In a monolayer proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0471cc3cf765c3cb318619ac1eea3fc5
https://pubmed.ncbi.nlm.nih.gov/7743502
https://pubmed.ncbi.nlm.nih.gov/7743502
Autor:
M J, Lynch, L, Pelosi, J M, Carboni, J, Merwin, K, Coleman, R C, Wang, P F, Lin, D L, Henry, M G, Brattain
Publikováno v:
Cancer research. 53(17)
FET cells are well differentiated human adenocarcinoma cells whose growth is partially inhibited (50-60%) by transforming growth factor-beta 1 (TGF-beta 1). In exponentially growing cultures, TGF-beta 1 induces the expression of transforming growth f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0237febbedb52c5cdc5823282da02ec4
https://pubmed.ncbi.nlm.nih.gov/8358733
https://pubmed.ncbi.nlm.nih.gov/8358733