Zobrazeno 1 - 10
of 35
pro vyhledávání: '"M G, Akimov"'
Publikováno v:
Russian Chemical Bulletin. 71:2395-2403
Autor:
Chandi C. Mandal, G. N. Zinchenko, Vladimir V. Bezuglov, Polina V Dudina, Alina M. Gamisonia, M. G. Akimov, Natalia Gretskaya
Publikováno v:
Doklady Biochemistry and Biophysics. 493:167-170
The influence of the cellular cholesterol content on the cytotoxicity of endovanilloids acyldopamines was studied in MDA-MB-231 and MCF 10A cells. The activity of acyldopamines depends on the cellular cholesterol content, and a decrease in cholestero
Autor:
Irina A. Fedorova-Gogolina, Alina M. Gamisonia, Chupalav M. Eldarov, M. G. Akimov, Mikhail Bobrov, Marina N. Yushina, Vladimir V. Bezuglov, Gennady T. Sukhikh, S. V. Pavlovich, Natalia Gretskaya
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10648, p 10648 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10648, p 10648 (2021)
Endometriosis is characterized by the formation and development of endometrial tissues outside the uterus, based on an imbalance between proliferation and cell death, leading to the uncontrolled growth of ectopic foci. The potential target for the re
Autor:
M. G. Akimov, L. A. Sviridova, Maria S. Dudina, Konstantin A. Kochetkov, Polina S. Protopopova, Elizaveta K. Melnikova
Publikováno v:
Mendeleev Communications. 30:347-349
Boron trifluoride-catalyzed amidoalkylation of indole derivatives with 5-hydroxy-1-phenylimidozolidin-2-one affords new biheterocycles with a direct C–C bond. Among them, 3- or 2-(2-oxoimidazolidin-5-yl)indoles manifest antiinflammatory activity wi
Autor:
L. V. Kovalenko, M. G. Akimov, A. V. Kalistratova, Alina M. Gamisoniya, Tatiana S. Gerasimova, Maxim Oshchepkov, Yuri A. Demidov
Publikováno v:
Mendeleev Communications. 30:153-155
A series of aryl-substituted ureas and carbamates containing chlorinated aromatic and modified imidazolidinone moieties were synthesized. These compounds were found to be cytotoxic to breast cancer cell line MDA-MB-231, glioblastoma U-87 MG and neuro
Publikováno v:
Russian Journal of Bioorganic Chemistry. 45:416-424
Dopamine transporter is a transmembrane protein associated with regulation of dopaminergic signal transmission by dopamine reuptake from the synaptic cleft back into cytosol. Some neurological disorders, for example Parkinson’s disease, are charact
Autor:
M. G. Akimov, A. M. Ashba, E. V. Fomina-Ageeva, N. M. Gretskaya, N. F. Myasoedov, V. V. Bezuglov
Publikováno v:
Доклады Академии наук. 485:625-628
It was established that in neurodegeneration models in the human neuron-like cell line SH-SY5Y, amide derivatives of arachidonic and docosahexaenoic acids were inactive in experiments with MPP+ and CoCl2 but protected from H2O2. The protective activi
Autor:
Vladimir V. Bezuglov, M. G. Akimov, Fomina-Ageeva Ev, N. F. Myasoedov, A. M. Ashba, Natalia Gretskaya
Publikováno v:
Doklady Biochemistry and Biophysics. 485:141-144
It was established that in neurodegeneration models in the human neuron-like cell line SH-SY5Y, amide derivatives of arachidonic and docosahexaenoic acids were inactive in experiments with MPP+ and CoCl2 but protected from H2O2. The protective activi
Publikováno v:
NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY.
Autor:
Polina V Dudina, Alina M. Gamisonia, Anastasia A Gaydaryova, M. G. Akimov, G. N. Zinchenko, Andrey S. Kuznetsov, Vladimir V. Bezuglov, Natalia Gretskaya
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 622, p 622 (2021)
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 622, p 622 (2021)
GPR55 is a GPCR of the non-CB1/CB2 cannabinoid receptor family, which is activated by lysophosphatidylinositol (LPI) and stimulates the proliferation of cancer cells. Anandamide, a bioactive lipid endocannabinoid, acts as a biased agonist of GPR55 an