Zobrazeno 1 - 10
of 27
pro vyhledávání: '"M Fleur du Pré"'
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0266543 (2022)
BackgroundCeliac disease is an autoimmune enteropathy driven by dietary intake of gluten proteins. Typical histopathologic features are villous flattening, crypt hyperplasia and infiltration of inflammatory cells in the intestinal epithelium and lami
Externí odkaz:
https://doaj.org/article/d3fca8985a4e418da1abb290ba72482d
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259082 (2021)
A hallmark of celiac disease is the gluten-dependent production of antibodies specific for deamidated gluten peptides (DGP) and the enzyme transglutaminase 2 (TG2). Both types of antibodies are believed to result from B cells receiving help from glut
Externí odkaz:
https://doaj.org/article/be49347ce9df44428d5f10923a025e4f
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134922 (2015)
A hallmark of the gluten-driven enteropathy celiac disease is autoantibody production towards the enzyme transglutaminase 2 (TG2) that catalyzes the formation of covalent protein-protein cross-links. Activation of TG2-specific B cells likely involves
Externí odkaz:
https://doaj.org/article/b35cf1b619f24db1a7766060b94a664b
Autor:
Marieke A van Leeuwen, M Fleur du Pré, Roy L van Wanrooij, Lilian F de Ruiter, H Rolien C Raatgeep, Dicky J Lindenbergh-Kortleve, Chris J Mulder, Lissy de Ridder, Johanna C Escher, Janneke N Samsom
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68432 (2013)
BACKGROUND: Celiac disease (CD) is an intestinal inflammation driven by gluten-reactive CD4(+) T cells. Due to lack of selective markers it has not been determined whether defects in inducible regulatory T cell (Treg) differentiation are associated w
Externí odkaz:
https://doaj.org/article/262ed0b6d37a4f688fa9507069969150
Autor:
Kristin Støen Gunnarsen, Inger Sandlie, M. Fleur du Pré, Knut E.A. Lundin, Jeliazko R. Jeliazkov, Geir Åge Løset, Ludvig M. Sollid, Alisa E. Dewan, Jamie Rossjohn, Rahel Frick, Lene Støkken Høydahl, Sheraz Yaqub, Grete Berntsen, Jan Petersen, Carmen Llerena, Terje Frigstad, Erik S. Vik, Jeffrey J. Gray, Shraddha Kumari, Jørgen Jahnsen
Publikováno v:
Sci Immunol
Antibodies specific for peptides bound to human leukocyte antigen (HLA) molecules are valuable tools for studies of antigen presentation and may have therapeutic potential. Here, we generated human T-cell receptor (TCR)-like antibodies towards the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afd629469de6e29e24ac424678e853d
http://hdl.handle.net/10852/91221
http://hdl.handle.net/10852/91221
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259082 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
A hallmark of celiac disease is the gluten-dependent production of antibodies specific for deamidated gluten peptides (DGP) and the enzyme transglutaminase 2 (TG2). Both types of antibodies are believed to result from B cells receiving help from glut
Publikováno v:
ImmunoHorizons. 5(1)
The human MHC class II molecule HLA-DQ2.5 is implicated in multiple autoimmune disorders, including celiac disease, type 1 diabetes, and systemic lupus erythematosus. The pathogenic contribution of HLA-DQ2.5 in many of these disorders is not fully un
Autor:
Lars Fugger, M. Fleur du Pré, Marie K. Johannesen, Christian B. Lindstad, Ludvig M. Sollid, Shuo-Wang Qiao
Publikováno v:
European journal of immunologyReferences. 51(4)
We created a TCR transgenic mouse with CD4+ T cells recognizing the immunodominant DQ2.5-glia-ω2 gluten epitope. We show that these cells respond to deamidated gluten feed in vivo and compare them to previously published α2- and γ1-specific mice.
Autor:
Jorunn Stamnaes, Sunniva F. Amundsen, M. Fleur du Pré, Ludvig M. Sollid, Liv Kleppa, Rasmus Iversen
Publikováno v:
Gastroenterology. 159(2)