Zobrazeno 1 - 10
of 77
pro vyhledávání: '"M F Good"'
Publikováno v:
The Journal of Immunology. 159:5535-5544
We have investigated the proliferative and Th cell responses to the Plasmodium chabaudi adami DS homologue of the Plasmodium falciparum apical membrane Ag 1 (AMA-1), a leading malaria vaccine candidate. Immunodominant T cell epitopes were defined fol
Autor:
C Hirunpetcharat, J H Tian, D C Kaslow, N van Rooijen, S Kumar, J A Berzofsky, L H Miller, M F Good
Publikováno v:
The Journal of Immunology. 159:3400-3411
The 19-kDa carboxyl-terminal fragment of the merozoite surface protein-1 (MSP1) is a leading malaria vaccine candidate but is unable to induce immunity in all monkeys or all strains of mice. The mechanism of immunity is unclear, although data show th
Publikováno v:
The Journal of Immunology. 157:1176-1183
The C-terminal 19-kDa, epidermal growth factor-like region of the merozoite surface protein 1 (MSP1) has been used as a vaccine to induce protective immunity to Plasmodium yoelii in mice and to Plasmodium falciparum in monkeys. To analyze the mechani
Autor:
Bart J. Currie, M. F. Good, A Manmontri, S Hunsakunachai, D Martin, Sumalee Pruksakorn, Evelyn R. Brandt, A Galbraith, Chanika Phornphutkul
Publikováno v:
The Lancet. 344:639-642
Rheumatic fever and rheumatic heart disease remain very common in developing countries, and a vaccine to protect against these disorders would have a great impact on public health. A vaccine must target the M protein of group A streptococci (Streptoc
Autor:
I A Quakyi, J Currier, A Fell, D W Taylor, T Roberts, R A Houghten, R D England, J A Berzofsky, L H Miller, M F Good
Publikováno v:
The Journal of Immunology. 153:2082-2092
T cells are thought to be of central importance in malaria immunity. Peptides copying malaria protein sequences often stimulate human CD4+ T cells and it was thought that they represented T cell epitopes present in the parasite and may thus have part
Autor:
Graham Brown, M. F. Good
Publikováno v:
Internal Medicine Journal. 32:129-131
Publikováno v:
The Journal of Immunology. 149:2729-2735
To identify conserved T and B cell epitopes on the M protein of group A beta-hemolytic streptococci, overlapping synthetic peptides that span the conserved carboxyl-terminal segment of the M-5 protein were constructed and used to immunize a panel of
Publikováno v:
The Journal of Immunology. 148:907-913
PBL from individuals with no history of malaria exposure, as well as cord blood lymphocytes, were tested for proliferation to T cell epitopes from the malaria circumsporozoite proteins of Plasmodium falciparum and Plasmodium vivax. Cells from many in