Zobrazeno 1 - 10
of 19
pro vyhledávání: '"M F, Miles"'
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Ethanol’s anxiolytic actions contribute to increased consumption and the development of Alcohol Use Disorder (AUD). Our laboratory previously identified genetic loci contributing to the anxiolytic-like properties of ethanol in BXD recombinant inbre
Externí odkaz:
https://doaj.org/article/eceff5a414db4ab5a69c1f3baa44d923
Publikováno v:
Genes, brain, and behavior. 13(2)
Mortality from tobacco smoking remains the leading cause of preventable death in the world, yet current cessation therapies are only modestly successful, suggesting new molecular targets are needed. Genetic analysis of gene expression and behavior id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1926edc7810a980bc15becb35ce1b834
https://pubmed.ncbi.nlm.nih.gov/24289814
https://pubmed.ncbi.nlm.nih.gov/24289814
Publikováno v:
International review of neurobiology. 104
Postgenomic studies of the function of genes and their role in disease have now become an area of intense study since efforts to define the raw sequence material of the genome have largely been completed. The use of whole-genome approaches such as mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94ce74a2fd66d1b7c9abf4cd0fd860bf
https://pubmed.ncbi.nlm.nih.gov/23195313
https://pubmed.ncbi.nlm.nih.gov/23195313
Autor:
M F, Miles
Publikováno v:
Journal of the Royal Society of Medicine. 87:161-163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbfd1cf3142fe35e54613296ad1880f5
https://doi.org/10.1177/014107689408700317
https://doi.org/10.1177/014107689408700317
Publikováno v:
International review of neurobiology. 48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f205a5680838986f73adc42a5439bc06
https://pubmed.ncbi.nlm.nih.gov/11526739
https://pubmed.ncbi.nlm.nih.gov/11526739
Publikováno v:
Alcoholism, clinical and experimental research. 24(12)
Changes in brain gene expression are thought to be responsible for the tolerance, dependence, and neurotoxicity produced by chronic alcohol abuse, but there has been no large scale study of gene expression in human alcoholism.RNA was extracted from p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33becac7f7511423b1aa5eb843f74446
https://pubmed.ncbi.nlm.nih.gov/11141048
https://pubmed.ncbi.nlm.nih.gov/11141048
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 292(1)
Chronic exposure to ethanol increases transcription of the molecular chaperone Hsc70 in NG108-15 neuroblastoma X glioma cells. This and other ethanol-induced changes in gene expression may contribute to central nervous system tolerance and dependence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ad6b654428e264afcde5b93f68b8dab
https://pubmed.ncbi.nlm.nih.gov/10604945
https://pubmed.ncbi.nlm.nih.gov/10604945
Publikováno v:
The Journal of biological chemistry. 271(5)
GRP78, a molecular chaperone expressed in the endoplasmic reticulum, is a "glucose-regulated protein" induced by stress responses that deplete glucose or intracisternal calcium or otherwise disrupt glycoprotein trafficking. Previously we showed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a22d89badefb76adf7c4231d3174c8f
https://pubmed.ncbi.nlm.nih.gov/8576245
https://pubmed.ncbi.nlm.nih.gov/8576245
Publikováno v:
Molecular pharmacology. 46(5)
Previously we found that ethanol increases expression of the constitutive 70-kDa heat shock protein (Hsc70) in NG108-15 neuroblastoma x glioma cells. We suggested that known ethanol actions on cellular protein trafficking may relate to Hsc70 inductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d82ec3e0a36b94bf08f34e789f19446
https://pubmed.ncbi.nlm.nih.gov/7969074
https://pubmed.ncbi.nlm.nih.gov/7969074
Publikováno v:
EXS. 71
Our studies in the NG108-15 neuroblastoma x glioma cell line previously showed that the molecular chaperonin, Hsc70, is an ethanol-responsive gene (EtRG) regulated at the level of transcription by ethanol. We recently identified two related molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e78133dd0ed788dce0f6eb413c80c36
https://pubmed.ncbi.nlm.nih.gov/8032172
https://pubmed.ncbi.nlm.nih.gov/8032172