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Isolation and characterization of 2'-fluoro-, 2'-amino-, and 2'-fluoro-/amino-modified RNA ligands to human IFN-gamma that inhibit receptor binding

Autor: M F Kubik, C Bell, T Fitzwater, S R Watson, D M Tasset

Publikováno v: The Journal of Immunology. 159:259-267

CD4+ Th cells produce cytokines that play a pivotal role in the induction and regulation of cell-mediated and humoral immunity. Th1 cells, characterized by their secretion of IFN-gamma, induce macrophage cytotoxicity, delayed hypersensitivity, and en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cdf628c6b74c376bd623817e5ae6c6bf
https://doi.org/10.4049/jimmunol.159.1.259

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Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB)

Autor: M. F. Kubik, J. P. Hoeffler, M.-A. H. Matthews, Audrey A. Franklin, Martine N. Uittenbogaard, Jennifer K. Nyborg, Pongsak Utaisincharoen, W. S. Dynan, Anne Brauweiler

Publikováno v: Journal of Biological Chemistry. 268:21225-21231

The human T-cell leukemia virus type I (HTLV-I)-encoded transcriptional activator protein Tax is strongly implicated in HTLV-I pathogenesis. Tax regulates HTLV-I gene expression through three 21-base pair (bp) repeat enhancer elements located in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::583acdbaabee8e310a70c6854cbcbfc7
https://doi.org/10.1016/s0021-9258(19)36914-5

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Isolation and characterization of 2'-fluoro-, 2'-amino-, and 2'-fluoro-/amino-modified RNA ligands to human IFN-gamma that inhibit receptor binding

Autor: M F, Kubik, C, Bell, T, Fitzwater, S R, Watson, D M, Tasset

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 159(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f6f022b816f049112ffab7dbe1b50e9
https://pubmed.ncbi.nlm.nih.gov/9200462

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Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB)

Autor: A A, Franklin, M F, Kubik, M N, Uittenbogaard, A, Brauweiler, P, Utaisincharoen, M A, Matthews, W S, Dynan, J P, Hoeffler, J K, Nyborg

Publikováno v: The Journal of biological chemistry. 268(28)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::35053620f1a879c02202e207fb0e501d
https://pubmed.ncbi.nlm.nih.gov/8407959

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