Zobrazeno 1 - 10
of 23
pro vyhledávání: '"M F, Jarvis"'
Autor:
D L Donnelly-Roberts, M F Jarvis
Publikováno v:
British Journal of Pharmacology. 151:571-579
ATP-sensitive P2X7 receptors are localized on cells of immunological origin including peripheral macrophages and glial cells in the CNS. Activation of P2X7 receptors leads to rapid changes in intracellular calcium concentrations, release of the proin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::856877ba81830445a1471a46d3d2ea9a
https://doi.org/10.1038/sj.bjp.0707265
https://doi.org/10.1038/sj.bjp.0707265
Autor:
K L, Chu, J, Xu, J, Frost, L, Li, E, Gomez, M J, Dart, M F, Jarvis, M D, Meyer, S, McGaraughty
Publikováno v:
European journal of pain (London, England). 19(5)
The noradrenergic system contributes to pain modulation, but the roles of its specific adrenoceptors are still being defined. We have identified a novel, potent (rat EC50 = 4.3 nM) and selective α2B receptor agonist, A-1262543, to further explore th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d778b563880a1b5c33dadaf116bd8c8b
https://pubmed.ncbi.nlm.nih.gov/25154730
https://pubmed.ncbi.nlm.nih.gov/25154730
Publikováno v:
European journal of pain (London, England). 17(5)
Microglia serve as macrophage-like cells in the central nervous system, and activation of microglial cells in the spinal cord may contribute to ongoing pain following peripheral trauma or nerve injury. Following pronociceptive stimulation, activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d26cc6108bd9a16d426dd2ac75174b5
https://pubmed.ncbi.nlm.nih.gov/23526770
https://pubmed.ncbi.nlm.nih.gov/23526770
Autor:
Raymond D. Youssefyeh, Christopher J. Burns, Daniel L. Cheney, M. F. Jarvis, J. S. Kim, H. W. Pauls, A. Assal
Publikováno v:
Calcified Tissue International. 52:372-377
The present studies characterize the binding of [14C]citric acid to synthetic hydroxyapatite (HA) crystals. [14C]Citric acid specifically bound to HA and was dependent upon the concentration of HA in the assay. The binding of [14C] citric acid to HA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f1411c49ca277099528e15cc0dbd94
https://doi.org/10.1007/bf00310202
https://doi.org/10.1007/bf00310202
Autor:
M F, Jarvis, M, Williams
Publikováno v:
IDrugs : the investigational drugs journal. 1(6)
This meeting was the second in four months to cover the role of P2 purinoreceptors in tissue function and pathophysiology, the previous being the Sixth International Symposium on Adenosine and Adenine Nucleotides held in Ferrara, Italy in May. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2c3009c5bb6999407e6b35dca41ae47
https://pubmed.ncbi.nlm.nih.gov/18465618
https://pubmed.ncbi.nlm.nih.gov/18465618
Autor:
D L, Donnelly-Roberts, M F, Jarvis
Publikováno v:
British journal of pharmacology. 151(5)
ATP-sensitive P2X(7) receptors are localized on cells of immunological origin including peripheral macrophages and glial cells in the CNS. Activation of P2X(7) receptors leads to rapid changes in intracellular calcium concentrations, release of the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fc31c77433e9668675c1f30e63388cc
https://pubmed.ncbi.nlm.nih.gov/17471177
https://pubmed.ncbi.nlm.nih.gov/17471177
Autor:
S, McGaraughty, M F, Jarvis
Publikováno v:
Drug newsperspectives. 18(8)
Acute systemic administration of a novel and highly selective non-nucleotide P2X(3)/P2X(2/3) receptor antagonist, A-317491, has been shown to reduce chronic hyperalgesia and allodynia in several animal models of pathological pain in the absence of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a391084d09025e5479de5b92ad85a53
https://pubmed.ncbi.nlm.nih.gov/16391720
https://pubmed.ncbi.nlm.nih.gov/16391720
Publikováno v:
British journal of pharmacology. 132(7)
1. Adenosine (ADO) receptor activation modulates sensory transmission in the dorsal horn. Little is known about the circumstances underlying release of the purine. The present study was conducted to investigate the effect of a novel and potent non-nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36b903ad5f208be675e91021f4bd47de
https://pubmed.ncbi.nlm.nih.gov/11264257
https://pubmed.ncbi.nlm.nih.gov/11264257
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(2)
Adenosine (ADO) is a homeostatic inhibitory autocoid that is released at sites of inflammation and tissue injury, and exerts anti-inflammatory effects via multiple interactions at ADO receptor subtypes. Inhibition of ADO kinase (AK) increases extrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a74f39eac64097d1bf833a8d44c94553
https://pubmed.ncbi.nlm.nih.gov/11160636
https://pubmed.ncbi.nlm.nih.gov/11160636
Autor:
S, McGaraughty, K L, Chu, C T, Wismer, J, Mikusa, C Z, Zhu, M, Cowart, E A, Kowaluk, M F, Jarvis
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(2)
The present study investigated 1) antihyperalgesic actions of a novel and selective adenosine kinase (AK) inhibitor, A-134974 (IC(50) = 60 pM), in the carrageenan model of thermal hyperalgesia; 2) effects of A-134974 on locomotor activity; and 3) rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbeeb138a3f407ef6da31b6e0adb97b6
https://pubmed.ncbi.nlm.nih.gov/11160637
https://pubmed.ncbi.nlm.nih.gov/11160637