Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease

Autor: Daniel Roca-Lema, Macarena Quiroga, Vineeta Khare, Andrea Díaz-Díaz, Aida Barreiro-Alonso, Andrea Rodríguez-Alonso, Ángel Concha, Gabriela Romay, M. Esperanza Cerdán, Christoph Gasche, Angélica Figueroa

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Abstract The E3 ubiquitin-ligases are important for cellular protein homeostasis and their deregulation is implicated in cancer. The E3 ubiquitin-ligase Hakai is involved in tumour progression and metastasis, through the regulation of the tumour supp

Externí odkaz: https://doaj.org/article/58d34e961d5a459f9da045abe6c74ca8

Differential Characteristics of HMGB2 Versus HMGB1 and their Perspectives in Ovary and Prostate Cancer

Autor: María Quindós-Varela, M. Esperanza Cerdán, Aida Barreiro-Alonso, María Cámara-Quílez, Esther Rodríguez-Bemonte, Mónica Lamas-Maceiras

Publikováno v: Current Medicinal Chemistry. 27:3271-3289

We have summarized common and differential functions of HMGB1 and HMGB2 proteins with reference to pathological processes, with a special focus on cancer. Currently, several “omic” approaches help us compare the relative expression of these 2 pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a402f5a7a574316d38b0fb4a5564e83c
https://doi.org/10.2174/0929867326666190123120338

HMGB1 Protein Interactions in Prostate and Ovary Cancer Models Reveal Links to RNA Processing and Ribosome Biogenesis through NuRD, THOC and Septin Complexes

Autor: M. Esperanza Cerdán, Lidia Lorenzo-Catoira, Aida Barreiro-Alonso, Mónica Lamas-Maceiras, Mercedes Pardo, Jyoti S. Choudhary, Lu Yu

Publikováno v: RUC. Repositorio da Universidade da Coruña
Universitat Oberta de Catalunya (UOC)
Cancers
Volume 13
Issue 18
Cancers, Vol 13, Iss 4686, p 4686 (2021)

Simple Summary HMGB1 over-expression is associated to prostate and ovary cancers: in this work, using a proteomic approach, we aimed to discover new protein interactions that might contribute to understand the oncogenic function of HMGB1 in cancers m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4b6ea99bb08888f00226bf43cd7c4a
http://hdl.handle.net/2183/29212

High Mobility Group B Proteins, Their Partners, and Other Redox Sensors in Ovarian and Prostate Cancer

Autor: Ángel Vizoso-Vázquez, Mónica Lamas-Maceiras, Aida Barreiro-Alonso, Esther Rodríguez-Belmonte, María Quindós, M. Esperanza Cerdán

Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)

Cancer cells try to avoid the overproduction of reactive oxygen species by metabolic rearrangements. These cells also develop specific strategies to increase ROS resistance and to express the enzymatic activities necessary for ROS detoxification. Oxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570c821dbc02ca75f2c80794d302dcea
https://doi.org/10.1155/2016/5845061

Structural features of Aspergillus niger β-galactosidase define its activity against glycoside linkages

Autor: M. Esperanza Cerdán, Mercedes Ramírez-Escudero, Julia Sanz-Aparicio, Agustín Rico-Díaz, Ángel Vizoso-Vázquez, Manuel Becerra

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

β-Galactosidases are biotechnologically interesting enzymes that catalyze the hydrolysis or transgalactosylation of β-galactosides. Among them, the Aspergillus niger β-galactosidase (AnβGal) belongs to the glycoside hydrolase family 35 (GH35) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381babf2069423258ff8a01f0276b81b
http://hdl.handle.net/10261/165815