Zobrazeno 1 - 10
of 495
pro vyhledávání: '"M Engelen"'
Autor:
Matthias M. Engelen, Charlotte Van Edom, Andreas Verstraete, Peter Verhamme, Thomas Vanassche
Publikováno v:
Thrombosis Update, Vol 15, Iss , Pp 100171- (2024)
Anticoagulant therapy has always been tightly connected with bleeding risk, as two sides of the same coin. New insights in thrombosis and hemostasis prompted the development of intrinsic pathway inhibitors that promise to uncouple thrombosis and hemo
Externí odkaz:
https://doaj.org/article/48ebe812dce24abc9abe7d06a049a07d
Autor:
Anne C. Fledderus, Anna Linn Widdershoven, Oren Lapid, Corstiaan C. Breugem, Suzanne G. M. A. Pasmans, Chantal M. A. M. van der Horst, Marc M. Engelen, Phyllis I. Spuls
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-17 (2022)
Abstract Background A congenital melanocytic naevus (CMN) is a rare skin condition that can be associated with abnormalities of the central nervous system (CNS). These anomalies can sometimes cause severe complications, and rarely death. Adequate inf
Externí odkaz:
https://doaj.org/article/05a57f40430d47f3ae9ab0308e89d2bc
Autor:
Matthias M. Engelen, Quentin Van Thillo, Albrecht Betrains, Iwein Gyselinck, Caroline P. Martens, Valérie Spalart, Anna Ockerman, Caroline Devooght, Joost Wauters, Jan Gunst, Carine Wouters, Christophe Vandenbriele, Steffen Rex, Laurens Liesenborghs, Alexander Wilmer, Philippe Meersseman, Greet Van den Berghe, Dieter Dauwe, Ann Belmans, Michiel Thomeer, Tom Fivez, Dieter Mesotten, David Ruttens, Luc Heytens, Ilse Dapper, Sebastiaan Tuyls, Brecht De Tavernier, Peter Verhamme, Thomas Vanassche, DAWn Consortium Members
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 7, Pp n/a-n/a (2022)
Abstract Background Thromboinflammation plays a central role in severe COVID‐19. The kallikrein pathway activates both inflammatory pathways and contact‐mediated coagulation. We investigated if modulation of the thromboinflammatory response impro
Externí odkaz:
https://doaj.org/article/0b44d597e02c4aa1ae0a47b3c5ef8724
Autor:
Caroline P. Martens, Pierre Van Mol, Joost Wauters, Els Wauters, Tanja Gangnus, Bernard Noppen, Hanne Callewaert, Jean H.M. Feyen, Laurens Liesenborghs, Elisabeth Heylen, Sander Jansen, Leydi Carolina Velásquez Pereira, Sirima Kraisin, Ipek Guler, Matthias M. Engelen, Anna Ockerman, Anke Van Herck, Robin Vos, Christophe Vandenbriele, Philippe Meersseman, Greet Hermans, Alexander Wilmer, Kimberly Martinod, Bjoern B. Burckhardt, Marc Vanhove, Marc Jacquemin, Peter Verhamme, Johan Neyts, Thomas Vanassche
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104195- (2022)
Summary: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the angiotensin-converting enzyme 2 (ACE2) receptor, a critical component of the kallikrein-kinin system. Its dysregulation may lead to increased vascular perm
Externí odkaz:
https://doaj.org/article/e22bccf7e13b4f4e9d17aa33606b5009
Autor:
Anna Ockerman, Thomas Vanassche, Melisa Garip, Christophe Vandenbriele, Matthias M Engelen, Jeroen Martens, Constantinus Politis, Reinhilde Jacobs, Peter Verhamme
Publikováno v:
Thrombosis Journal, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Objectives We review the evidence for tranexamic acid (TXA) for the treatment and prevention of bleeding caused by surgery, trauma and bleeding disorders. We highlight therapeutic areas where evidence is lacking and discuss safety issues, pa
Externí odkaz:
https://doaj.org/article/32be3382a67441d19afc0f1cfacda7d6
Autor:
Matthias M. Engelen, Christophe Vandenbriele, Valérie Spalart, Caroline P. Martens, Bert Vandenberk, Pieter Sinonquel, Natalie Lorent, Paul De Munter, Rik Willems, Joost Wauters, Alexander Wilmer, Dieter Dauwe, Jan Gunst, Ipek Guler, Stefan Janssens, Kimberly Martinod, Griet Pieters, Kathelijne Peerlinck, Peter Verhamme, Thomas Vanassche
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 3, Pp n/a-n/a (2022)
Abstract Background Venous thromboembolism (VTE) frequently occurs in hospitalized patients with coronavirus disease 2019 (COVID‐19). The optimal dose of anticoagulation for thromboprophylaxis in COVID‐19 is unknown. Aims To report VTE incidence
Externí odkaz:
https://doaj.org/article/2c1238428a3c4e769f7bde88fe726124
Autor:
T. Vanassche, M. M. Engelen, Q. Van Thillo, J. Wauters, J. Gunst, C. Wouters, C. Vandenbriele, S. Rex, L. Liesenborghs, A. Wilmer, P. Meersseman, G. Van den Berghe, D. Dauwe, G. Verbeke, M. Thomeer, T. Fivez, D. Mesotten, D. Ruttens, L. Heytens, I. Dapper, S. Tuyls, B. De Tavernier, P. Verhamme, DAWn consortium members
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background The peak of the global COVID-19 pandemic has not yet been reached, and many countries face the prospect of a second wave of infections before effective vaccinations will be available. After an initial phase of viral replication, s
Externí odkaz:
https://doaj.org/article/db7c466255624cae9d005a020f65877e
Autor:
Iwein Gyselinck, Laurens Liesenborghs, Ann Belmans, Matthias M. Engelen, Albrecht Betrains, Quentin Van Thillo, Pham Anh Hong Nguyen, Pieter Goeminne, Ann-Catherine Soenen, Nikolaas De Maeyer, Charles Pilette, Emmanuelle Papleux, Eef Vanderhelst, Aurélie Derweduwen, Patrick Alexander, Bernard Bouckaert, Jean-Benoît Martinot, Lynn Decoster, Kurt Vandeurzen, Rob Schildermans, Peter Verhamme, Wim Janssens, Robin Vos
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2022)
Background and objectives Azithromycin was rapidly adopted as a repurposed drug to treat coronavirus disease 2019 (COVID-19) early in the pandemic. We aimed to evaluate its efficacy in patients hospitalised for COVID-19. Methods In a series of random
Externí odkaz:
https://doaj.org/article/84e4d414b91948c480d8de7f8a801790
Autor:
Bert Vandenberk, Matthias M. Engelen, Greet Van De Sijpe, Jonas Vermeulen, Stefan Janssens, Thomas Vanassche, Peter Verhamme, Paul De Munter, Natalie Lorent, Rik Willems
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 37, Iss , Pp 100912- (2021)
Background: ECG abnormalities in COVID-19 have been widely reported, however data after discharge is limited. The aim was to describe ECG abnormalities on admission and following recovery of COVID-19, and their associated mortality. Methods: All pati
Externí odkaz:
https://doaj.org/article/346b31eca5d0421a993df0577b3748da
Autor:
Laurens Liesenborghs, Isabel Spriet, Dirk Jochmans, Ann Belmans, Iwein Gyselinck, Laure-Anne Teuwen, Sebastiaan ter Horst, Erwin Dreesen, Tatjana Geukens, Matthias M. Engelen, Ewout Landeloos, Vincent Geldhof, Helga Ceunen, Barbara Debaveye, Bert Vandenberk, Lorenz Van der Linden, Sofie Jacobs, Lana Langendries, Robbert Boudewijns, Thuc Nguyen Dan Do, Winston Chiu, Xinyu Wang, Xin Zhang, Birgit Weynand, Thomas Vanassche, Timothy Devos, Geert Meyfroidt, Wim Janssens, Robin Vos, Pieter Vermeersch, Joost Wauters, Geert Verbeke, Paul De Munter, Suzanne J.F. Kaptein, Joana Rocha-Pereira, Leen Delang, Eric Van Wijngaerden, Johan Neyts, Peter Verhamme
Publikováno v:
EBioMedicine, Vol 69, Iss , Pp 103454- (2021)
Externí odkaz:
https://doaj.org/article/a9dc46fa677a4f63b1d97aa898d674d9