Zobrazeno 1 - 10 of 119 pro vyhledávání: '"M Elizabeth Fini"'
1
Akademický článek
Dynasore protects the ocular surface against damaging oxidative stress.
Autor: Andrew Webster, Shravan K Chintala, Jasmine Kim, Michelle Ngan, Tatsuo Itakura, Noorjahan Panjwani, Pablo Argüeso, Joseph T Barr, Shinwu Jeong, M Elizabeth Fini
Publikováno v: PLoS ONE, Vol 13, Iss 10, p e0204288 (2018)
Water soluble "vital" dyes are commonly used clinically to evaluate health of the ocular surface; however, staining mechanisms remain poorly understood. Recent evidence suggests that sublethal damage stimulates vital dye uptake by individual living c
Externí odkaz: https://doaj.org/article/bd50d6f17f2341efb6b31a56250f4033
Zobrazit plný text záznamu
2
Akademický článek
Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.
Autor: Nitin Patel, Tatsuo Itakura, Shinwu Jeong, Chun-Peng Liao, Pradip Roy-Burman, Ebrahim Zandi, Susan Groshen, Jacek Pinski, Gerhard A Coetzee, Mitchell E Gross, M Elizabeth Fini
Publikováno v: PLoS ONE, Vol 10, Iss 2, p e0117758 (2015)
Prostate cancer (PCa) is the second-leading cause of cancer-related mortality, after lung cancer, in men from developed countries. In its early stages, primary tumor growth is dependent on androgens, thus generally can be controlled by androgen depri
Externí odkaz: https://doaj.org/article/ffbac6972cdd427fb5688afa9e5b89dc
Zobrazit plný text záznamu
3
Akademický článek
Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye.
Autor: Aditi Bauskar, Wendy J Mack, Jerome Mauris, Pablo Argüeso, Martin Heur, Barbara A Nagel, Grant R Kolar, Martin E Gleave, Takahiro Nakamura, Shigeru Kinoshita, Janet Moradian-Oldak, Noorjahan Panjwani, Stephen C Pflugfelder, Mark R Wilson, M Elizabeth Fini, Shinwu Jeong
Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0138958 (2015)
Dry eye is a common disorder caused by inadequate hydration of the ocular surface that results in disruption of barrier function. The homeostatic protein clusterin (CLU) is prominent at fluid-tissue interfaces throughout the body. CLU levels are redu
Externí odkaz: https://doaj.org/article/3122b1b0557c4829993a05a07f8b26ae
Zobrazit plný text záznamu
4
Akademický článek
GPR158, an orphan member of G protein-coupled receptor Family C: glucocorticoid-stimulated expression and novel nuclear role.
Autor: Nitin Patel, Tatsuo Itakura, Jose M Gonzalez, Stephen G Schwartz, M Elizabeth Fini
Publikováno v: PLoS ONE, Vol 8, Iss 2, p e57843 (2013)
Members of the large G protein-coupled receptor (GPCR) clan are implicated in many physiological and disease processes, making them important therapeutic drug targets. In the present study, we follow up on results of a pilot study suggesting a functi
Externí odkaz: https://doaj.org/article/30505addeabd4fa083ea197500693da2
Zobrazit plný text záznamu
5
Dynasore Protects Corneal Epithelial Cells Subjected to Hyperosmolar Stress in an In Vitro Model of Dry Eye Epitheliopathy
Autor: Rafael Martinez-Carrasco, M. Elizabeth Fini
Publikováno v: International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4754
Epitheliopathy at the ocular surface is a defining sign of dry eye disease, a common disorder that affects 10% to 30% of the world’s population. Hyperosmolarity of the tear film is one of the main drivers of pathology, with subsequent endoplasmic r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115f838ba5fab1ef648405032775b701
Zobrazit plný text záznamu
7
Recombinant Human Clusterin Seals Damage to the Ocular Surface Barrier in a Mouse Model of Ophthalmic Preservative-Induced Epitheliopathy
Autor: Shravan K. Chintala, Jinhong Pan, Sandeep Satapathy, Rebecca Condruti, Zixuan Hao, Pei-wen Liu, Christian F. O’Conner, Joseph T. Barr, Mark R. Wilson, Shinwu Jeong, M. Elizabeth Fini
Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 981
There is a significant unmet need for therapeutics to treat ocular surface barrier damage, also called epitheliopathy, due to dry eye and related diseases. We recently reported that the natural tear glycoprotein CLU (clusterin), a molecular chaperone
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38fec1c08ac84fcff0805ad046c9b503
https://doi.org/10.3390/ijms24020981
Zobrazit plný text záznamu
8
Clusterin, Other Extracellular Chaperones, and Eye Disease
Autor: Mark R. Wilson, Sandeep Satapathy, Shinwu Jeong, M. Elizabeth Fini
Publikováno v: Prog Retin Eye Res
Proteostasis refers to all the processes that maintain the correct expression level, location, folding and turnover of proteins, essential to organismal survival. Both inside cells and in body fluids, molecular chaperones play key roles in maintainin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad2e82f04d6f4342ade1d0c018566c0
https://europepmc.org/articles/PMC9184305/
Zobrazit plný text záznamu
9
Transcriptome Analysis of Pterygium and Pinguecula Reveals Evidence of Genomic Instability Associated with Chronic Inflammation
Autor: Maria Fernanda Suarez, Esteban Medina, José Echenique, Mariano Irós, Horacio M. Serra, M. Elizabeth Fini, Juan Manuel López
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 12090, p 12090 (2021)
Solar damage due to ultraviolet radiation (UVR) is implicated in the development of two proliferative lesions of the ocular surface: pterygium and pinguecula. Pterygium and pinguecula specimens were collected, along with adjacent healthy conjunctiva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f03dd5f80ef978bdd3d13ad2b6f2b9
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje