Zobrazeno 1 - 10
of 114
pro vyhledávání: '"M Elizabeth, Fini"'
Autor:
Maria Fernanda Suarez, Tatsuo Itakura, Satyabrata Pany, Shinwu Jeong, Shravan K. Chintala, Michael B. Raizman, Steven Riesinger, Tsvetelina Lazarova, José Echenique, Horacio M. Serra, W. Daniel Stamer, M. Elizabeth Fini
Publikováno v:
Stresses, Vol 3, Iss 3, Pp 629-652 (2023)
Elevated intraocular pressure (IOP), the major risk factor for glaucoma, is caused by decreased outflow through the trabecular meshwork (TM). The pathophysiology of ocular hypertension has been linked to stress pathways, including fibrosis, calcifica
Externí odkaz:
https://doaj.org/article/d7b8cb97eb0046e480769cd972be43a1
Autor:
Rafael Martinez-Carrasco, Satyanarayan Rachagani, Surinder K. Batra, Pablo Argüeso, M. Elizabeth Fini
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Membrane-associated mucins (MAMs) are proposed to play critical roles at the ocular surface; however, in vivo evidence has been lacking. Here we investigate these roles by phenotyping of a Muc4 KO mouse. Histochemical analysis for expression
Externí odkaz:
https://doaj.org/article/64eeb30c8e774af2a5129cb12c6ad5f6
Publikováno v:
Free Radical Biology and Medicine. 179:421-425
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::107b812de968ea2ed0258a36499d73cf
https://doi.org/10.1016/j.freeradbiomed.2021.10.030
https://doi.org/10.1016/j.freeradbiomed.2021.10.030
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4754
Volume 24
Issue 5
Pages: 4754
Epitheliopathy at the ocular surface is a defining sign of dry eye disease, a common disorder that affects 10% to 30% of the world’s population. Hyperosmolarity of the tear film is one of the main drivers of pathology, with subsequent endoplasmic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115f838ba5fab1ef648405032775b701
Autor:
Andrew Webster, Shravan K Chintala, Jasmine Kim, Michelle Ngan, Tatsuo Itakura, Noorjahan Panjwani, Pablo Argüeso, Joseph T Barr, Shinwu Jeong, M Elizabeth Fini
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204288 (2018)
Water soluble "vital" dyes are commonly used clinically to evaluate health of the ocular surface; however, staining mechanisms remain poorly understood. Recent evidence suggests that sublethal damage stimulates vital dye uptake by individual living c
Externí odkaz:
https://doaj.org/article/bd50d6f17f2341efb6b31a56250f4033
Publikováno v:
Prog Retin Eye Res
Proteostasis refers to all the processes that maintain the correct expression level, location, folding and turnover of proteins, essential to organismal survival. Both inside cells and in body fluids, molecular chaperones play key roles in maintainin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad2e82f04d6f4342ade1d0c018566c0
https://europepmc.org/articles/PMC9184305/
https://europepmc.org/articles/PMC9184305/
Autor:
Maria Fernanda Suarez, Esteban Medina, José Echenique, Mariano Irós, Horacio M. Serra, M. Elizabeth Fini, Juan Manuel López
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 12090, p 12090 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 12090, p 12090 (2021)
Solar damage due to ultraviolet radiation (UVR) is implicated in the development of two proliferative lesions of the ocular surface: pterygium and pinguecula. Pterygium and pinguecula specimens were collected, along with adjacent healthy conjunctiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f03dd5f80ef978bdd3d13ad2b6f2b9
Autor:
Shravan K. Chintala, Jinhong Pan, Sandeep Satapathy, Rebecca Condruti, Zixuan Hao, Pei-wen Liu, Christian F. O’Conner, Joseph T. Barr, Mark R. Wilson, Shinwu Jeong, M. Elizabeth Fini
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 981
There is a significant unmet need for therapeutics to treat ocular surface barrier damage, also called epitheliopathy, due to dry eye and related diseases. We recently reported that the natural tear glycoprotein CLU (clusterin), a molecular chaperone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38fec1c08ac84fcff0805ad046c9b503
https://doi.org/10.3390/ijms24020981
https://doi.org/10.3390/ijms24020981