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Publikováno v:
Toxicological Sciences. 17:159-176
Autor:
M E Sutphin, Morrow B. Thompson, Rick Irwin, J.D. Prejean, June K. Dunnick, Herschell D. Giles
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 17(1)
Toxicity studies of 3'-azido-2',3'-dideoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC) were conducted in F344/N rats and B6C3F1 mice. The drugs were administered as single agents and in combination. In all studies, animals were treated by oral gav