Zobrazeno 1 - 10
of 29
pro vyhledávání: '"M E Pickup"'
Publikováno v:
Current Medical Research and Opinion. 8:412-416
An open crossover study was carried out in 8 normal volunteer subjects to compare faecal blood loss resulting from tilcotil (Ro12-0068), a new anti-inflammatory agent, and from enteric-coated aspirin. After a 1-week run-in period, subjects were alloc
Publikováno v:
Annals of the Rheumatic Diseases. 40:480-488
Biochemical and clinical changes have been monitored in 30 patients with rheumatoid arthritis treated with either hydroxychloroquine or sodium aurothiomalate over a period of 6 months. Acute-phase reactants improved in both treatment groups, while se
Publikováno v:
Rheumatology International. 3:145-149
Groups of 15 patients with active rheumatoid arthritis were treated for 24 weeks with zinc sulphate, trien, captopril, clozic in two doses or a combination of D-penicillamine and hydroxychloroquine. Serum histidine levels were monitored along with me
Plasma viscosity--a new appraisal of its use as an index of disease activity in rheumatoid arthritis
Publikováno v:
Annals of the Rheumatic Diseases. 40:272-275
The suitability of the plasma viscosity (PV) test has been examined in relation to the more commonly used erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) estimations as a diagnostic aid in 120 outpatients with rheumatoid arthritis (
Autor:
Howard A. Bird, M. E. Pickup, J. R. Lowe, R. J. Marwah, J. S. Dixon, H. Al-Shakarchi, Verna Wright
Publikováno v:
European Journal of Clinical Pharmacology. 23:321-325
1. Two oral corticosteroids, prednisolone (8 mg/day) and betamethasone (1 mg/day) have been compared in terms of efficacy and adrenal suppressive activity when used in chronic oral dosage in rheumatoid arthritis. 2. 20 patients were entered to a sing
Publikováno v:
European Journal of Clinical Pharmacology. 12:213-219
The pharmacokinetics of prednisolone elimination have been studied in both arthritic patients and normal volunteers using tritiated prednisolone alone, and in conjunction with unlabelled prednisolone in doses of 0.15 mg-kg-1 and 0.3 mg-kg-1 body weig
Publikováno v:
Annals of the Rheumatic Diseases. 39:281-284
In view of the claim that alclofenac has a specific antirheumatoid action a detailed biochemical study has been made over a 6-month period of 2 groups of patients with rheumatoid arthritis receiving either alclofenac or D-penicillamine for the first
Publikováno v:
Rheumatology. 17:23-28
It has been recommended that benorylate may be administered with hot beverages to overcome the problem of its relative unpalatability. Urine salicylate recovery used as a measure of bioavailability in 20 normal subjects has shown that hot coffee has
Autor:
Howard A. Bird, F. S. Jeunet, D. B. Galloway, V. Wright, M. E. Pickup, L. Bamford, M. McEvoy, E. W. Gasgoine
Publikováno v:
Current Medical Research and Opinion. 8:9-13
An open crossover study was carried out in 6 normal volunteers to measure faecal blood loss caused by tilcotil (Ro 12-0068), a new anti-inflammatory drug, compared with that caused by enteric-coated aspirin. Subjects were allocated at random to recei
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 3:99-101
Antipyrine studies were conducted in patients with rheumatoid arthritis to assess the enzyme inducing potential of long-term therapy with prednisolone. No significant difference in any pharmacokinetic parameter for antipyrine between prednisolone-tre