Zobrazeno 1 - 10
of 36
pro vyhledávání: '"M E Pape"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 12, Pp 2502-2515 (1997)
Low density lipoprotein (LDL) reduction independent of LDL receptor regulation was investigated using HMG-CoA reductase inhibitors in LDL receptor-deficient mice. In males, LDL cholesterol dose-dependently decreased with atorvastatin treatment after
Externí odkaz:
https://doaj.org/article/7134225cd4744b8bb794c59eb39272fd
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 11, Pp 2365-2373 (1997)
We have developed a cDNA-dependent scintillation proximity assay (SPA) for rabbit apolipoprotein A-I that follows a classic radioimmunoassay scheme, in that antiserum and radiolabeled ligand are used in a process to quantify a source containing unlab
Externí odkaz:
https://doaj.org/article/88f5fd37341645f3b78599ec76d8da6e
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 4, Pp 823-838 (1995)
A human cDNA clone (K1) was recently isolated that encodes functional acyl-CoA:cholesterol acyltransferase (ACAT) protein (Chang et al. J. Biol. Chem. 1993. 268: 20747-20755). We used the K1 clone to screen a rabbit liver cDNA library and isolated a
Externí odkaz:
https://doaj.org/article/fe9cbf6c731747dda4882ccbd5cdd106
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 7, Pp 1274-1282 (1994)
Apolipoprotein A-I (apoA-I), the primary protein of high density lipoprotein, originates from intestine and liver of almost all mammalian species. In contrast to most species, intact rabbit liver is only capable of producing minute amounts of apoA-I
Externí odkaz:
https://doaj.org/article/bf7a55451e2044db9d57d5b27eea112c
Autor:
M E Pape, Jeffrey C. Hanselman, T J Rea, Brian R. Krause, David A. Schwab, Charles L. Bisgaier
Publikováno v:
Life Sciences. 66:1683-1694
Past studies have shown that a high saturated fatty acid diet containing coconut oil elevates plasma HDL cholesterol and apolipoprotein A-I (apoA-1) in rabbits through a mechanism involving increased synthesis. We have extended those studies by inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05d9dd5cdf7c3313c5077ddfceba655
https://doi.org/10.1016/s0024-3205(00)00491-4
https://doi.org/10.1016/s0024-3205(00)00491-4
Autor:
Catherine S. Sekerke, Charles L. Bisgaier, A. D. Essenburg, M E Pape, A Gee, Roger S. Newton, S Wölle, Bruce J. Auerbach
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 12, Pp 2502-2515 (1997)
Low density lipoprotein (LDL) reduction independent of LDL receptor regulation was investigated using HMG-CoA reductase inhibitors in LDL receptor-deficient mice. In males, LDL cholesterol dose-dependently decreased with atorvastatin treatment after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0bc2628306dac80526c218d40aac86
https://doi.org/10.1016/s0022-2275(20)30035-3
https://doi.org/10.1016/s0022-2275(20)30035-3
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 11, Pp 2365-2373 (1997)
We have developed a cDNA-dependent scintillation proximity assay (SPA) for rabbit apolipoprotein A-I that follows a classic radioimmunoassay scheme, in that antiserum and radiolabeled ligand are used in a process to quantify a source containing unlab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65cf88b586b81a331a829aa1417d986
https://doi.org/10.1016/s0022-2275(20)34950-6
https://doi.org/10.1016/s0022-2275(20)34950-6
Autor:
Kirstin D. Mazany, M E Pape, Kevin Jon Williams, C L Bisgaier, Thomas J. Rea, A. D. Essenburg, Wendi V. Rodrigueza
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:2132-2139
Abstract Phospholipid liposomes are synthetic mediators of “reverse” cholesterol transport from peripheral tissue to liver in vivo and can shrink atherosclerotic lesions in animals. Hepatic disposal of this cholesterol, however, has not been exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::facbdb83cf216a07ec3ae8bd6815474d
https://doi.org/10.1161/01.atv.17.10.2132
https://doi.org/10.1161/01.atv.17.10.2132
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1299:67-74
A partial rabbit cDNA clone (14b) for ACAT has been characterized and used to demonstrate that hepatic and aortic ACAT mRNA14b abundance increased 2-3-fold in rabbits receiving a high fat/high cholesterol-diet compared to chow fed animals (Pape et al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7475a23aaf2530be0a85342c4353b6
https://doi.org/10.1016/0005-2760(95)00190-5
https://doi.org/10.1016/0005-2760(95)00190-5
Autor:
M E Pape, B C Barnett, Todd Leff, A D Essenburg, B J Auerbach, Sabine Haubenwallner, L L Minton, R B DeMattos, B R Krause, Roger S. Newton
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 12, Pp 2541-2551 (1995)
For the last 30 years fibrates have been widely prescribed to treat human dyslipidemia. However, the primary mechanism by which they lower plasma lipid levels is still unknown. Studies with transgenic mice have suggested that changes in apoC-III expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071e8f3f6190c7acd1df6bd446d298a2
http://www.sciencedirect.com/science/article/pii/S0022227520410909
http://www.sciencedirect.com/science/article/pii/S0022227520410909