Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M E Lebsack"'
Publikováno v:
Arthritis & Rheumatism. 39:1092-1101
Objective. To preliminarily evaluate the safety and efficacy of different dose levels and dosing frequencies of recombinant human interleukin-1 receptor antagonist (rHuIL-1Ra) in the treatment of patients with rheumatoid arthritis (RA). Methods. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30585f55ddf7fd1fe4a0982d036d1c45
https://doi.org/10.1002/art.1780390704
https://doi.org/10.1002/art.1780390704
Autor:
Julie M. Vose, James R. Anderson, L. Garrison, M. E. Lebsack, J. E. Anderson, Philip J. Bierman, Frederick R. Appelbaum, James O. Armitage
Publikováno v:
Journal of Clinical Oncology. 14:520-526
PURPOSE A phase I/II study of PIXY321 following high-dose therapy (HDT) and autologous bone marrow transplantation (ABMT) was conducted to evaluate the safety and clinical potential of this agent. PATIENTS AND METHODS Fifty patients with Hodgkin's di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4c22d4e29ea937c13cb025116ef0eb
https://doi.org/10.1200/jco.1996.14.2.520
https://doi.org/10.1200/jco.1996.14.2.520
Autor:
Margaret Chrymko, M. E. Lebsack, Ralph Abadier, Kathleen A. Stringer, Donald F. Switzer, Allen J. Sedman
Publikováno v:
The Journal of Clinical Pharmacology. 31:607-610
The effect of administration of pirmenol, an extensively metabolized and plasma protein-bound antiarrhythmic agent, was evaluated in ten patients on chronic warfarin therapy. After a 3-week baseline period and 7 days of placebo administration, patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c960e4a48bce9a4b706e5fda02ebee
https://doi.org/10.1002/j.1552-4604.1991.tb03745.x
https://doi.org/10.1002/j.1552-4604.1991.tb03745.x
Autor:
C Nichols, C F LeMaistre, A Smith, M Lange, J. E. Anderson, J M Fernandez Ranada, Julie M. Vose, W Longo, L. Garrison, E A Copelan, A Granena, A N Pandite, D L Topolsky, T Ahmed, R. B. Geller, I Tabbara, P. J. Bierman, Patrick J. Stiff, M W Schuster, R A Beveridge, M. E. Lebsack, A. Keating
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 15(4)
PURPOSE A phase III trial to compare PIXY321 with granulocyte-macrophage colony-stimulating factor (GM-CSF) following high-dose therapy and autologous bone marrow transplant (ABMT) was conducted to evaluate the time to hematopoietic recovery. PATIENT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8efccef669779463619c68ef961455b
https://pubmed.ncbi.nlm.nih.gov/9193361
https://pubmed.ncbi.nlm.nih.gov/9193361
Publikováno v:
Arthritis and rheumatism. 39(7)
To preliminarily evaluate the safety and efficacy of different dose levels and dosing frequencies of recombinant human interleukin-1 receptor antagonist (rHuIL-1Ra) in the treatment of patients with rheumatoid arthritis (RA).One hundred seventy-five
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::654d0d5769d15663bd0702d4a22ab0f7
https://pubmed.ncbi.nlm.nih.gov/8670316
https://pubmed.ncbi.nlm.nih.gov/8670316
Autor:
Linda Welage, Jerome J. Schentag, David E. Nix, Allyn Norman, M. E. Lebsack, Bruce Ryerson, Roger D Toothaker, Allen J Sedman
Publikováno v:
Clinical pharmacology and therapeutics. 52(3)
The effect of gastric acidity on the oral absorption of the quinolone antibiotic enoxacin was evaluated in 12 healthy volunteers. In a randomized, crossover design, single 400 mg oral enoxacin doses were administered on four occasions: alone, after 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d594bd2c4f1e7251a11c7efc43fbf7bc
https://pubmed.ncbi.nlm.nih.gov/1526081
https://pubmed.ncbi.nlm.nih.gov/1526081
Autor:
Tsun Chang, M. E. Lebsack, Alien L. Goidfarb, Allen J. Sedman, Anne B. Cetnarowski-Cropp, Kathleen A. Stringer, Louis L. Raduiovic, Howard N. Bockbrader
Publikováno v:
Journal of clinical pharmacology. 32(1)
The potential for a drug—drug interaction between pirmenol, an extensively metabolized antiarrhythmic agent, and cimetidine, an inhibitor of hepatic drug-metabolizing enzymes, was evaluated in eight healthy adults. A single 150-mg oral dose of pirm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcb757a80f7edd395c105a63ca8e116
https://pubmed.ncbi.nlm.nih.gov/1740542
https://pubmed.ncbi.nlm.nih.gov/1740542
Publikováno v:
Biochemical pharmacology. 30(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80f5bd8670b0bfd6733fab58465692e8
https://pubmed.ncbi.nlm.nih.gov/7195708
https://pubmed.ncbi.nlm.nih.gov/7195708
Autor:
M E, Lebsack, A D, Anderson
Publikováno v:
Research communications in chemical pathology and pharmacology. 26(2)
The in vivo inhibition of low Km mitochondrial aldehyde dehydrogenase (AlDH) activity by pargyline was not maximal until more than 30 minutes after i.p. injection. Enzyme activity returned to control levels within 36 hours of drug injection but the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bee6803a8109474965c16c5b1243125c
https://pubmed.ncbi.nlm.nih.gov/523771
https://pubmed.ncbi.nlm.nih.gov/523771
Autor:
Thaddeus H. Grasela, A W Kinkel, J H Wilton, R W Schultz, A J Sedman, D J Thomas, M E Lebsack, Jerome J. Schentag
Publikováno v:
Antimicrobial agents and chemotherapy. 33(5)
Ten normal volunteers participated in a randomized, five-way crossover study to determine the effect of concurrent enoxacin and antacid or ranitidine administration on enoxacin absorption. The bioavailability of a single oral 400-mg enoxacin dose was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49dd91f763c3ad9981488f1e853d94d7
https://pubmed.ncbi.nlm.nih.gov/2751276
https://pubmed.ncbi.nlm.nih.gov/2751276