Zobrazeno 1 - 10
of 71
pro vyhledávání: '"M E Lamm"'
Publikováno v:
Journal of Clinical Investigation. 87:1819-1827
We sought to determine whether systemic administration of proteases ameliorates membranous nephritis induced in rats by immunization and challenge with cationic bovine gamma globulin, and whether targeting of protease to glomerular capillaries increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5574c0151178cdfa88a05e0d19476b7
https://doi.org/10.1172/jci115203
https://doi.org/10.1172/jci115203
Publikováno v:
The Journal of Immunology. 145:3684-3691
Oral tolerance, an important feature of the mucosal immune system, appears to protect against immune-mediated disease by blunting production of systemic IgG and IgM antibody directed toward immunogens chronically present at mucosal surfaces. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c71b4c12a7f33b36d52bde3775510e
https://doi.org/10.4049/jimmunol.145.11.3684
https://doi.org/10.4049/jimmunol.145.11.3684
Autor:
M E, Lamm
Publikováno v:
The American journal of physiology. 274(4)
The humoral arm of the mucosal immune system is principally composed of locally synthesized polymeric IgA, whose Fc portion is adapted for binding to the polymeric immunoglobulin receptor that is expressed on the basolateral surface of mucosal epithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23200473dab76846dc42c2541770cca7
https://pubmed.ncbi.nlm.nih.gov/9575841
https://pubmed.ncbi.nlm.nih.gov/9575841
Autor:
M. E. Lamm
Publikováno v:
Alimentary pharmacologytherapeutics. 11
SUMMARY Exogenous antigens can impinge upon the luminal surface of mucous membranes and to a limited degree, can even penetrate into the lamina propria. As a result of infection, microbial antigens can be present in mucosal epithelium or lamina propr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca188a26437eed1e5654285cfc69f03
https://pubmed.ncbi.nlm.nih.gov/9467977
https://pubmed.ncbi.nlm.nih.gov/9467977
Publikováno v:
Laboratory animal science. 46(2)
Mouse hepatitis virus (MHV) is a pervasive pathogen that causes morbidity and mortality in mouse colonies worldwide. Although it is not a major cause of mortality in immunocompetent mice, infections from MHV strains of lower virulence can be fatal to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::caee3f973635150e733abf7f947561b3
https://pubmed.ncbi.nlm.nih.gov/8723232
https://pubmed.ncbi.nlm.nih.gov/8723232
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(2)
Epithelial transport of polymeric IgA (pIgA) from its site of synthesis to the mucosal lumen is mediated by the polymeric Ig receptor (pIgR). During transcytosis, a disulfide bond forms between pIgR and pIgA, resulting in secretion of a covalently li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5241494d51d7ee0f4f7978ceaaf74a0f
https://pubmed.ncbi.nlm.nih.gov/7608548
https://pubmed.ncbi.nlm.nih.gov/7608548
Publikováno v:
Advances in experimental medicine and biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73c6150fe7687bdf7692c0ee028cae39
https://pubmed.ncbi.nlm.nih.gov/8526010
https://pubmed.ncbi.nlm.nih.gov/8526010
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(1)
We recently demonstrated that the polymeric IgR (pIgR) mediates epithelial transcytosis of immune complexes (IC) containing dimeric IgA (dIgA). In vivo, this "excretory" pathway could allow direct elimination of IgA IC at the mucosal sites where they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71b5c594dd463ef24426b0faaa31dac7
https://pubmed.ncbi.nlm.nih.gov/8254208
https://pubmed.ncbi.nlm.nih.gov/8254208
Publikováno v:
Hepatology (Baltimore, Md.). 19(1)
The polymeric immunoglobulin receptor on rat hepatocytes binds dimeric IgA on the sinusoidal surface and mediates its transport to the canaliculus, where the complex of dimeric IgA and secretory component, the cleaved extracellular domain of polymeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1dd30add960f27aa64e0f8d6905b6a11
https://pubmed.ncbi.nlm.nih.gov/8276353
https://pubmed.ncbi.nlm.nih.gov/8276353
Autor:
M E Lamm
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 6(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1efa9ff2b7734c6b1f6d6e3af47c38
https://pubmed.ncbi.nlm.nih.gov/1563589
https://pubmed.ncbi.nlm.nih.gov/1563589