Zobrazeno 1 - 10
of 30
pro vyhledávání: '"M E Horowitz"'
Autor:
L H, Wexler, T F, DeLaney, M, Tsokos, N, Avila, S M, Steinberg, L, Weaver-McClure, J, Jacobson, P, Jarosinski, Y M, Hijazi, F M, Balis, M E, Horowitz
Publikováno v:
Cancer. 78(4)
This study was conducted to determine the feasibility of, and improve outcome by, incorporating ifosfamide and etoposide (IE) into the therapy of newly diagnosed patients with Ewing's sarcoma family of tumors of bone and soft tissue.Fifty-four newly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b9016cbdcf643a6adbe2ffc60a090c9
https://pubmed.ncbi.nlm.nih.gov/8756388
https://pubmed.ncbi.nlm.nih.gov/8756388
Autor:
S M, Blaney, P C, Phillips, R J, Packer, R L, Heideman, S L, Berg, P C, Adamson, J C, Allen, S E, Sallan, R I, Jakacki, B J, Lange, G H, Reaman, M E, Horowitz, D G, Poplack, F M, Balis
Publikováno v:
Cancer. 78(3)
Topotecan is a topoisomerase I inhibitor that has good penetration across the blood-brain barrier and significant antitumor activity against human brain tumor xenografts. In a Phase I trial in children with refractory cancer, topotecan was well toler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc3a93dd72591c5149a35cd9ee18ae3e
https://pubmed.ncbi.nlm.nih.gov/8697400
https://pubmed.ncbi.nlm.nih.gov/8697400
Autor:
P K, Duffner, M E, Cohen, R A, Sanford, M E, Horowitz, J P, Krischer, P C, Burger, H S, Friedman, L E, Kun
Publikováno v:
Medical and pediatric oncology. 25(1)
Eleven infants with pineoblastomas were treated with prolonged postoperative chemotherapy in an attempt to delay radiation and reduce neurotoxicity. These infants were part of the Pediatric Oncology Group infant brain tumor study but the outcome of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0dd3353bfe219f98ebfcbca50d0322a6
https://pubmed.ncbi.nlm.nih.gov/7753001
https://pubmed.ncbi.nlm.nih.gov/7753001
Autor:
B I, Razzouk, R L, Heideman, H S, Friedman, J J, Jenkins, L E, Kun, D L, Fairclough, M E, Horowitz
Publikováno v:
Cancer. 75(11)
Chemotherapy may be used to delay the need for cranial irradiation in infants and young children with malignant central nervous system (CNS) tumors. The polyfunctional alkylator thiotepa (TT) possesses significant in vitro and in vivo activity in man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45b4a8d1ef404163e176e51d1bcd18b9
https://pubmed.ncbi.nlm.nih.gov/7743483
https://pubmed.ncbi.nlm.nih.gov/7743483
Autor:
P K, Duffner, L E, Kun, P C, Burger, M E, Horowitz, M E, Cohen, R A, Sanford, J P, Krischer, R K, Mulhern, H E, James, H L, Rekate
Publikováno v:
Pediatric neurosurgery. 22(4)
Eight infants with choroid plexus carcinomas were treated with surgery, prolonged postoperative chemotherapy and delayed radiation. The results suggest that some infants with choroid plexus carcinomas can be successfully treated with multimodality th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01626e426132427c63ce2881978b0556
https://pubmed.ncbi.nlm.nih.gov/7619719
https://pubmed.ncbi.nlm.nih.gov/7619719
Publikováno v:
Cancer. 72(4)
Since the advent of multiagent adjuvant chemotherapy, survival among patients with localized osteosarcoma has improved to 60% or more. Pulmonary relapse, the most common cause of treatment failure, is associated with less than 25% long-term survival;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c24c256753a12f510089211be42faa3
https://pubmed.ncbi.nlm.nih.gov/8339211
https://pubmed.ncbi.nlm.nih.gov/8339211
Autor:
R L, Heideman, R J, Packer, G H, Reaman, J C, Allen, B, Lange, M E, Horowitz, S M, Steinberg, A, Gillespie, E H, Kovnar, F M, Balis
Publikováno v:
Cancer. 72(1)
Both thiotepa and its active metabolite, tepa, efficiently cross the blood-brain barrier. After intravenous administration, the cerebrospinal fluid concentrations achieved are nearly identical to those in plasma. This provides a strong rationale for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73d1299e02ea86634667c7c6dd5b8713
https://pubmed.ncbi.nlm.nih.gov/8508417
https://pubmed.ncbi.nlm.nih.gov/8508417
Autor:
C A, Felix, E A, Strauss, D, D'Amico, M, Tsokos, S, Winter, T, Mitsudomi, M M, Nau, D L, Brown, A M, Leahey, M E, Horowitz
Publikováno v:
Oncogene. 8(5)
A novel germline p53 splicing mutation was identified in a pediatric patient with two metachronous primary cancers that are constituent tumors of the Li-Fraumeni syndrome. Genomic DNA from the second tumor showed the same mutation and loss of heteroz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e05fdd6c15e2af08223c4b238e09e12c
https://pubmed.ncbi.nlm.nih.gov/8479743
https://pubmed.ncbi.nlm.nih.gov/8479743
We have examined a wide range of cultured human tumor cell lines and found that a specific subset of tumors expresses the cholecystokinin (CCK) gene. All neuroepitheliomas (eight) and Ewing sarcoma (eight) cell lines that were tested express CCK RNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86569391c0c2a32eda1da921dc3ff5c
https://europepmc.org/articles/PMC402109/
https://europepmc.org/articles/PMC402109/
Autor:
S J, Kellie, E H, Kovnar, L E, Kun, M E, Horowitz, R L, Heideman, E C, Douglass, J W, Langston, R A, Sanford, J J, Jenkins, D L, Fairclough
Publikováno v:
Cancer. 69(4)
Of 29 consecutive children treated for malignant primary tumors of the central nervous system (CNS) at this institution, postoperative examination showed radiographic or cytologic evidence of neuraxis dissemination in 10 (34%). Given the historically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cd5189d785ffb66cfca68444961c92d
https://pubmed.ncbi.nlm.nih.gov/1735073
https://pubmed.ncbi.nlm.nih.gov/1735073