Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M E Hemling"'
Autor:
Christopher L. Brummel, M. E. Hemling, S. A. Carr, Stephen J. Benkovic, Walter Johnson, G. D. Roberts, D. Gaitanopoulos, Nicholas Winograd, John C. Vickerman, J. Weinstock
Publikováno v:
Analytical Chemistry. 68:237-242
Electrospray, matrix-assisted laser desorption, and time-of-flight secondary ion mass spectrometry have been explored as possible methods for the identification of active members of molecular combinatorial libraries. All three methods are found to yi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05440ae22bd6a402bf307c7b7b908ff
https://doi.org/10.1021/ac950998u
https://doi.org/10.1021/ac950998u
Autor:
Steven A. Carr, Priscilla Offen, Brad Carte, Laurie MacKenzie, M. E. Hemling, David E. Berry, Charles W. DeBrosse
Publikováno v:
ChemInform. 22
A novel flavone-C-glycoside, aciculatin (1), has been isolated from the methylene chloride extract of Chrysopogon aciculatis (Poaceae) collected in the Philippines. The structure of 1 was determined by analysis of spectral data. Aciculatin exhibits c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::104419a8377cf2aeb27ab7fa0b61743c
https://doi.org/10.1002/chin.199124256
https://doi.org/10.1002/chin.199124256
Autor:
P. Offen, G. C. Simolike, B. C. M. Potts, M. E. Hemling, D. J. Faulkner, J. A. Chan, T. A. Francis
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2373b2090e98a5a851ec545e25b5d990
https://doi.org/10.1002/chin.199143242
https://doi.org/10.1002/chin.199143242
Autor:
A. Freyer, D. J. Faulkner, G. A. Hofmann, M. R. Mattern, B. K. Carte, M. E. Hemling, R. S. Compagnone, G. Chan
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bf2fbc82b8310314469b1723c25d518
https://doi.org/10.1002/chin.199515285
https://doi.org/10.1002/chin.199515285
Autor:
Charles W. DeBrosse, M. E. Hemling, Steven A. Carr, David E. Berry, Priscilla Offen, Laurie MacKenzie, Brad Carte
Publikováno v:
Tetrahedron. 47:1815-1822
A novel flavone-C-glycoside, aciculatin (1), has been isolated from the methylene chloride extract of Chrysopogon aciculatis (Poaceae) collected in the Philippines. The structure of 1 was determined by analysis of spectral data. Aciculatin exhibits c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6056b4ab0de73ae5a207d304c6ea597
https://doi.org/10.1016/s0040-4020(01)96096-x
https://doi.org/10.1016/s0040-4020(01)96096-x
Autor:
B. Wang, Ren Xie, Daniel F. Veber, Dennis S. Yamashita, S. D.‐H. Shi, C. Hissong, Thaddeus A. Tomaszek, M. E. Hemling, Chad Quinn, H. Lin
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 63(3)
The design, synthesis, enzymologic, and protein mass spectrometric characterization of benzodioxocin-3-one and N-acyl-3-amino-3-buten-2-one inhibitors of the cysteine protease cathepsin K are described. The benzodioxocin-3-one ring system is chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe12333bc97f3a3e56a67fb67b1913ee
https://pubmed.ncbi.nlm.nih.gov/15049838
https://pubmed.ncbi.nlm.nih.gov/15049838
Autor:
M.W. Lark, Chao-Pin Lee, L.D Davis, M. E. Hemling, Ian E. James, G Trescher, Antonia Marzulli, Dennis S. Yamashita, B.R. Bradley, Thaddeus A. Tomaszek, H.-J. Oh, Kevin L. Salyers, B. Wang, R. C. Haltiwanger, Mark A. Levy, Cheryl A. Janson, R.A. Dodds, F Lin, H.-Y. Cheng, M. Gowen, Jin Zeng, S M Hwang, Catherine J. Gress, David G. Tew, Stephen M. LoCastro, J. W. Proksch, Beverley Smith, Ward W. Smith, Chad Quinn, Robert W. Marquis, Karl F. Erhard, Karla J. D'Alessio, Baoguang Zhao, Simon M. Blake, Michael S. McQueney, Cummings Maxwell D, Daniel F. Veber, Keith W. Ward, Ru Yu
Publikováno v:
Journal of medicinal chemistry. 44(9)
The synthesis, in vitro activities, and pharmacokinetics of a series of azepanone-based inhibitors of the cysteine protease cathepsin K (EC 3.4.22.38) are described. These compounds show improved configurational stability of the C-4 diastereomeric ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869edd5069e660d644d9b841b87cde41
https://pubmed.ncbi.nlm.nih.gov/11311061
https://pubmed.ncbi.nlm.nih.gov/11311061
Autor:
G W, Chan, S, Mong, M E, Hemling, A J, Freyer, P H, Offen, C W, DeBrosse, H M, Sarau, J W, Westley
Publikováno v:
Journal of natural products. 56(1)
Three new imidazole alkaloids, leucettamines A [1] and B [2] and leucettamidine [3], have been isolated from the Palauan sponge Leucetta microraphis. Their structures were established on the basis of extensive spectral analyses. Leucettamine A showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd48d662a8d5614947807829827bb1a7
https://pubmed.ncbi.nlm.nih.gov/8383730
https://pubmed.ncbi.nlm.nih.gov/8383730
Autor:
M Suzuki, K L Rinehart, Norman Latov, M E Hemling, Lorenza Freddo, Tatsuo Kohriyama, K Kon, Toshio Ariga, M Saito, S Ando
Publikováno v:
Journal of Biological Chemistry. 262:848-853
In some patients with neuropathy and plasma cell dyscrasia, the serum IgM M-proteins are known to bind to the myelin associated glycoprotein and to peripheral nerve glycolipids. We have isolated two acidic glycolipids which bind to the M-protein from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89c451e4cd01782403d3422a256cd6e2
https://doi.org/10.1016/s0021-9258(19)75864-5
https://doi.org/10.1016/s0021-9258(19)75864-5
Autor:
K Anumula, Steven A. Carr, M E Hemling, R W Sweet, P Taylor, G Folena-Wasserman, Michael J. Huddleston, John R. Barr
Publikováno v:
Journal of Biological Chemistry. 264:21286-21295
The primary structure of a soluble form of the CD4 receptor (sCD4) expressed in Chinese hamster ovary cells has been confirmed by mass spectrometric peptide mapping and and tandem mass spectrometry. These studies corroborated 95% of the 369-amino aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4044aa749be3845683a6278dbac3d1d5
https://doi.org/10.1016/s0021-9258(19)30077-8
https://doi.org/10.1016/s0021-9258(19)30077-8