Zobrazeno 1 - 10 of 364 pro vyhledávání: '"M E Gurney"'
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Akademický článek
The Spatial‐Temporal Alternative Splicing Profile Reveals the Functional Diversity of FXR1 Isoforms in Myogenesis.
Autor: Wang, Wei1,2,3 (AUTHOR), Fan, Xinhao1,2,3 (AUTHOR), Liu, Weiwei3,4 (AUTHOR), Huang, Yuxin3,4 (AUTHOR), Zhao, Shuhong2 (AUTHOR), Yang, Yalan1,3 (AUTHOR) yangyalan@caas.cn, Tang, Zhonglin1,3 (AUTHOR) tangzhonglin@caas.cn
Publikováno v: Advanced Science. 12/18/2024, Vol. 11 Issue 47, p1-19. 19p.
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2
Mutant CuZn superoxide dismutase in motor neuron disease
Autor: David A. Becker, M. E. Gurney, R. Liu, E. D. Hall, J. S. Althaus
Publikováno v: Journal of Inherited Metabolic Disease. 21:587-597
CuZn superoxide dismutase (CuZn SOD) is one of several antioxidant enzymes that defend the cell against damage by oxygen free radicals. Mutations of the SOD1 gene encoding CuZn SOD are found in patients with familial amyotrophic lateral sclerosis (FA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56331624d407467766ca4a0e3676bd86
https://doi.org/10.1023/a:1005475206997
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3
The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease
Autor: Zissimos Mourelatos, M E Gurney, Anna Stieber, Nicholas K. Gonatas, M. C. Dal Canto
Publikováno v: Proceedings of the National Academy of Sciences. 93:5472-5477
Dominant mutations of the SOD1 gene encoding Cu,Zn superoxide dismutase have been found in members of certain families with familial amyotrophic lateral sclerosis (ALS). To better understand the contribution of SOD1 mutations in the pathogenesis of f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50af31cc52a477e04803391919f4520d
https://doi.org/10.1073/pnas.93.11.5472
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4
Correction
Autor: M E, Gurney
Publikováno v: Science (New York, N.Y.). 269(5221)
In the report "Motor neuron degeneration in mice that express a human Cu, Zn super-oxide dismutase mutation" by M. E. Gurney et al. (17 June 1994, p. 1772)(1), a systematic, 10-fold error was made in calculating the dilutions of brain extract used fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76b1d70ffec1690713ab3c8fd4d38509
https://pubmed.ncbi.nlm.nih.gov/17789832
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6
What transgenic mice tell us about neurodegenerative disease
Autor: M E, Gurney
Publikováno v: BioEssays : news and reviews in molecular, cellular and developmental biology. 22(3)
The recent broad advance in our understanding of human neurodegenerative diseases is based on the application of a new molecular approach. Through linkage analysis, the genes responsible for Huntington's disease, the spinocerebellar ataxias, and fami
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4415f71b0c3fb294cdce450223770828
https://pubmed.ncbi.nlm.nih.gov/10684590
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7
Relationship of oxygen radical-induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS
Autor: E D, Hall, P K, Andrus, J A, Oostveen, T J, Fleck, M E, Gurney
Publikováno v: Journal of neuroscience research. 53(1)
Transgenic mice that overexpress a mutated human CuZn superoxide dismutase (SOD1) gene (gly93--ala) found in some patients with familial ALS (FALS) have been shown to develop motor neuron disease, as evidenced by motor neuron loss in the lumbar and c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a661b04f2c5758c22a1c821799d5c3a
https://pubmed.ncbi.nlm.nih.gov/9670993
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8
Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
Autor: E D, Hall, J A, Oostveen, M E, Gurney
Publikováno v: Glia. 23(3)
Transgenic mice that highly over-express a mutated human CuZn superoxide dismutase (SOD1) gene [gly93--ala; TgN(SOD1-G93A)G1H line] found in some patients with familial ALS (FALS) have been shown to develop motor neuron disease that is characterized
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::535a2b18ae80d74461c607106be8267e
https://pubmed.ncbi.nlm.nih.gov/9633809
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9
Akademický článek
Development of White Cabbage, Coffee, and Red Onion Extracts as Natural Phosphodiesterase-4B (PDE4B) Inhibitors for Cognitive Dysfunction: In Vitro and In Silico Studies.
Autor: Ahmad, Nazir1, Lesa, Kaisun Nesa2,3,4,5, Ujiantari, Navista Sri Octa1, Sudarmanto, Ari6, Fakhrudin, Nanang7,8, Ikawati, Zullies1 zullies_ikawati@ugm.ac.id
Publikováno v: Advances in Pharmacological & Pharmaceutical Sciences. 5/21/2024, Vol. 2024, p1-39. 39p.
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10
Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease
Autor: P H, Tu, M E, Gurney, J P, Julien, V M, Lee, J Q, Trojanowski
Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 76(4)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that primarily affects motor neurons in the spinal cord and brain stem. About 10% of all ALS cases are familial (FALS), inherited in an autosomal dominant manner. One fifth of FALS pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c6c557b6bef9e7c3abc8660fd36ad7c9
https://pubmed.ncbi.nlm.nih.gov/9111507
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