Zobrazeno 1 - 10 of 23 pro vyhledávání: '"M E, Varnes"'
1
MRI-guided radiofrequency thermal ablation of implanted VX2 liver tumors in a rabbit model: demonstration of feasibility at 0.2 T
Autor: E M, Merkle, D T, Boll, T, Boaz, J L, Duerk, Y C, Chung, G H, Jacobs, M E, Varnes, J S, Lewin
Publikováno v: Magnetic resonance in medicine. 42(1)
Successful radiofrequency (RF) thermal ablation was performed on VX2 tumors implanted in 23 rabbit livers under magnetic resonance (MR) guidance using a C-arm-shaped low-field 0.2 T system. RF application and immediate postprocedure MRI of all animal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::005206141ad34511423c542a7a45eb75
https://pubmed.ncbi.nlm.nih.gov/10398960
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2
Liver biopsy: effects of biopsy needle caliber on bleeding and tissue recovery
Autor: D Y Rowland, J R Haaga, D W Goodwin, Donna Plecha, M E Varnes
Publikováno v: Radiology. 204(1)
To evaluate different-caliber biopsy cutting needles in terms of the benefits and potential risk of bleeding in a swine model.A total of 190 sequential liver biopsy specimens were obtained in 11 Yorkshire pigs (weight, 50-70 lb [22.5-31.5 kg]) by usi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172a0964b7b1641628ee4c1c9212cf9c
https://pubmed.ncbi.nlm.nih.gov/9205229
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3
Insulin and insulin-like growth factor-1 (IGF-1) inhibit repair of potentially lethal radiation damage and chromosome aberrations and alter DNA repair kinetics in plateau-phase A549 cells
Autor: V R, Jayanth, C A, Belfi, A R, Swick, M E, Varnes
Publikováno v: Radiation research. 143(2)
Plateau-phase A549 cells exhibit a high capacity for repair of potentially lethal radiation damage (PLD) when allowed to recover in their own spent medium. Addition of either insulin or insulin-like growth factor-1 (IGF-1) to the spent medium 60 to 1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::497b8f48970e0cd6b4fa40dac41fa401
https://pubmed.ncbi.nlm.nih.gov/7631009
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4
Effects of extracellular and intracellular pH on repair of potentially lethal damage, chromosome aberrations and DNA double-strand breaks in irradiated plateau-phase A549 cells
Autor: V R, Jayanth, M T, Bayne, M E, Varnes
Publikováno v: Radiation research. 139(2)
Plateau-phase A549 cells exhibit a high capacity for repair of potentially lethal radiation damage (PLD). Previously it was found that PLD repair could be partially inhibited by increasing the extracellular pH (pHe) of the spent medium from its norma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e5df6a0539f74b30b2abb9df6337ca08
https://pubmed.ncbi.nlm.nih.gov/8052690
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5
Enhancement of photodynamic cell killing (with chloroaluminum phthalocyanine) by treatment of V79 cells with the ionophore nigericin
Autor: M E, Varnes, M E, Clay, K, Freeman, A R, Antunez, N L, Oleinick
Publikováno v: Cancer research. 50(5)
The K+/H+ ionophore nigericin dramatically increases killing of V79 cells by photodynamic therapy (PDT), when cells pretreated with 1 microM chloroaluminum phthalocyanine are incubated with nigericin before exposure to red light. Nigericin affects pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::29d0497edb895de807076a8a748cb6c7
https://pubmed.ncbi.nlm.nih.gov/2302719
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6
Interactions of the carcinogen 4-nitroquinoline 1-oxide with the non-protein thiols of mammalian cells
Autor: M E, Varnes, J E, Biaglow
Publikováno v: Cancer research. 39(8)
The carcinogen 4-nitroquinoline 1-oxide (4-NQO) was found to rapidly deplete non-protein thiols (NPSH) from Ehrlich ascites tumor cells and V79 Chinese hamster fibroblasts. The effects of NPSH on 4-NQO metabolism were studied by measuring 4-hydroxyam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7af3e050d961f6d167d3d1fa663ab025
https://pubmed.ncbi.nlm.nih.gov/110443
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7
The role of thiols in cellular response to radiation and drugs
Autor: J E, Biaglow, M E, Varnes, E P, Clark, E R, Epp
Publikováno v: Radiation research. 95(3)
Cellular nonprotein thiols (NPSH) consist of glutathione (GSH) and other low molecular weight species such as cysteine, cysteamine, and coenzyme A. GSH is usually less than the total cellular NPSH, and with thiol reactive agents, such as diethyl male
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d5cbfe6a54ed4f1a29a7437f68e559f3
https://pubmed.ncbi.nlm.nih.gov/6684310
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10
Nitroheterocycle metabolism in mammalian cells. Stimulation of the hexose monophosphate shunt
Autor: M E, Varnes, S W, Tuttle, J E, Biaglow
Publikováno v: Biochemical pharmacology. 33(10)
Misonidazole, SR-2508, nitrofurazone and other nitroheterocycles stimulated release of 14CO2 from [1-14C]glucose but not from [6-14C]glucose when incubated with mouse Ehrlich ascites cells or human A549 lung carcinoma cells in vitro. This demonstrate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::35296cc8e425c25a8471acf9bb6a4974
https://pubmed.ncbi.nlm.nih.gov/6428413
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