Zobrazeno 1 - 3
of 3
pro vyhledávání: '"M E, Rabaglia"'
Publikováno v:
Diabetes. 45:1783-1791
Publikováno v:
The Journal of endocrinology. 153(1)
Glucose can augment insulin secretion independently of K+ channel closure, provided cytoplasmic free Ca2+ concentration is elevated. A role for phospholipase C (PLC) in this phenomenon has been both claimed and refuted. Recently, we have shown a role
Publikováno v:
The Journal of biological chemistry. 267(18)
To investigate whether GTP concentrations can be a regulatory step in exocytotic hormone secretion, we treated isolated rat islets with mycophenolic acid (MPA) or mizoribine, two selective inhibitors of de novo GTP synthesis. When islets were culture