Zobrazeno 1 - 10
of 81
pro vyhledávání: '"M E, Kyle"'
Publikováno v:
Biochemical pharmacology. 40(6)
Over the course of 4 hr, the metabolism of acetaminophen (APAP) by cultured rat hepatocytes resulted in a depletion of protein thiols and an accumulation of oxidized glutathione (GSSG) in the medium. With 20 mM APAP, arylation and the formation of gl
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 62(6)
Publikováno v:
Molecular pharmacology. 37(3)
Pretreatment of cultured hepatocytes with the ferric iron chelator deferoxamine prevents the killing of the cells by tert-butyl hydroperoxide (TBHP). Incubation of the deferoxamine-pretreated hepatocytes in a serum-free medium containing only 0.25 nM
Autor:
Feng, Baoyi1,2,3 (AUTHOR), Dong, Tingting2,3,4 (AUTHOR), Song, Xinyu5 (AUTHOR), Zheng, Xiaofei1,2,3 (AUTHOR), Jin, Chenxi1,2,3 (AUTHOR), Cheng, Zhenzhe1,2,3 (AUTHOR), Liu, Yiqing1,2,3 (AUTHOR), Zhang, Wenjie5 (AUTHOR), Wang, Xueling2,3,4 (AUTHOR) wangxueling@sjtu.edu.cn, Tao, Yong1,2,3 (AUTHOR) taoyent@sjtu.edu.cn, Wu, Hao1,2,3 (AUTHOR) wuhao@shsmu.edu.cn
Publikováno v:
Advanced Science. 3/27/2024, Vol. 11 Issue 12, p1-17. 17p.
Publikováno v:
Geophysical Research Letters; 7/16/2024, Vol. 51 Issue 13, p1-10, 10p
Publikováno v:
Molecular pharmacology. 34(4)
The toxicity of acetaminophen was studied in hepatocytes cultured from phenobarbital-induced male rats. Such cells were less sensitive to acetaminophen than similar ones cultured from animals induced with 3-methylcholanthrene. In both cases, the toxi
Autor:
M E, Kyle, J J, Kocsis
Publikováno v:
Advances in experimental medicine and biology. 197
Autor:
M E, Kyle, J J, Kocsis
Publikováno v:
Toxicology and applied pharmacology. 81(2)
The administration of 500 mg/kg sodium [14C]salicylate to 3- and 12-month-old male rats produced proximal tubular necrosis in the older animals but only mild nonspecific cellular changes in the younger group. The onset of renal damage was similar for
Publikováno v:
Ecology & Evolution (20457758); Jun2024, Vol. 14 Issue 6, p1-14, 14p
Autor:
Guilloteau, Adrien1,2,3 (AUTHOR) adrien.guilloteau@chu-dijon.fr, Abrahamowicz, Michal4 (AUTHOR), Boussari, Olayide1,2,5,6 (AUTHOR), Jooste, Valérie1,2,5 (AUTHOR), Aparicio, Thomas7 (AUTHOR), Quantin, Catherine8,9,10,11 (AUTHOR), Le Malicot, Karine1,2,6 (AUTHOR), Binquet, Christine1,2,9,10 (AUTHOR)
Publikováno v:
BMC Medical Research Methodology. 1/9/2021, Vol. 21 Issue 1, p1-10. 10p.