Zobrazeno 1 - 9
of 9
pro vyhledávání: '"M E, Klotman"'
Publikováno v:
American journal of reproductive immunology (New York, N.Y. : 1989). 49(5)
Topical microbicides, designed for vaginal or rectal administration, are needed to prevent human immunodeficiency virus (HIV) and other sexually transmitted infections (STI). Presently marketed topical microbicides are cytotoxic and damage the vagina
Autor:
S, Jones, M E, Klotman
Publikováno v:
Journal of human virology. 4(4)
To determine the impact of genotypic resistance testing on physician selection of antiretroviral therapy.This was a prospective, observational study. A single genotypic resistance test was done when patients failed highly active antiretroviral therap
Autor:
M E, Klotman, P E, Klotman
Publikováno v:
Seminars in nephrology. 18(4)
Publikováno v:
Seminars in nephrology. 18(4)
In a very short period of time, availability of antiretroviral drugs has increased from one drug with very modest activity to 12 approved drugs with remarkable potency, particularly when used in combination. The additional availability of absolutely
Publikováno v:
Experimental nephrology. 5(6)
There are several obstacles that prevent the successful clinical application of gene therapy. Some of these challenges are unique to the particular disease and organ that is being targeted. Desirable characteristics of approaches aimed at delivery of
Autor:
S, Dhawan, B S, Weeks, F, Abbasi, H R, Gralnick, A L, Notkins, M E, Klotman, K M, Yamada, P E, Klotman
Publikováno v:
Virology. 197(2)
T cells interact with the extracellular matrix via integrin receptors and these interactions affect both cellular localization and proliferation. The importance of these interactions in retrovirus-induced diseases, however, remains less clear. In the
Publikováno v:
The Journal of biological chemistry. 268(7)
The HIV-1 transactivator protein Tat is essential for viral gene expression and replication. Tat is taken up by cells and transactivates the HIV-LTR promoter in the cell nucleus. The present studies show that cells adhere to both synthetic and recomb
Publikováno v:
Human Gene Therapy; 4/01/2004, Vol. 15 Issue 4, p361-372, 12p
Autor:
M E, Klotman, J D, Hamilton
Publikováno v:
Seminars in respiratory infections. 2(2)
Cytomegalovirus (CMV) is a common virus that asymptomatically infects the majority of the population by early adulthood. After initial infection, the virus remains in a latent state in the host and can be reactivated under a variety of conditions. In