Výsledky vyhledávání - "M E, Hasselmo"

Selective loss of cholinergic neurons projecting to the olfactory system increases perceptual generalization between similar, but not dissimilar, odorants

Autor: C, Linster, P A, Garcia, M E, Hasselmo, M G, Baxter

Publikováno v: Behavioral neuroscience. 115(4)

The neuromodulator acetylcholine is thought to modulate information processing in the olfactory system. The authors used 192 IgG-saporin, a lesioning agent selective for basal forebrain cholinergic neurons, to determine whether selective lesions of c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b430e961fced6e38407ccbed2ac5ff48
https://pubmed.ncbi.nlm.nih.gov/11508721

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Contribution of the cholinergic basal forebrain to proactive interference from stored odor memories during associative learning in rats

Autor: E, De Rosa, M E, Hasselmo, M G, Baxter

Publikováno v: Behavioral neuroscience. 115(2)

E. De Rosa and M. E. Hasselmo (2000) demonstrated that 0.25 mg/kg scopolamine (SCOP) selectively increased proactive interference (PI) from stored odor memories during learning. In the present study, rats with bilateral cholinergic lesions limited to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd445f4ed702f69b09bb0e231b938881
https://pubmed.ncbi.nlm.nih.gov/11345957

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A model for experience-dependent changes in the responses of inferotemporal neurons

Autor: V S, Sohal, M E, Hasselmo

Publikováno v: Network (Bristol, England). 11(3)

Neurons in inferior temporal (IT) cortex exhibit selectivity for complex visual stimuli and can maintain activity during the delay following the presentation of a stimulus in delayed match to sample tasks. Experimental work in awake monkeys has shown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af7de02794610820ad44f5a37fc028aa
https://pubmed.ncbi.nlm.nih.gov/11014667

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Muscarinic cholinergic neuromodulation reduces proactive interference between stored odor memories during associative learning in rats

Autor: E, De Rosa, M E, Hasselmo

Publikováno v: Behavioral neuroscience. 114(1)

Previous electrophysiological studies and computational modeling suggest the hypothesis that cholinergic neuromodulation may reduce olfactory associative interference during learning (M. E. Hasselmo, B. P. Anderson,J. M. Bower, 1992; M. E. HasselmoJ.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::099aef82ade999ba41d46ba232b0ddf7
https://pubmed.ncbi.nlm.nih.gov/10718260

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Neuromodulation and the hippocampus: memory function and dysfunction in a network simulation

Autor: M E, Hasselmo

Publikováno v: Progress in brain research. 121

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b0a73296c56bdeaf79d421a84203dfd7
https://pubmed.ncbi.nlm.nih.gov/10551017

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Bridging the gap: integrating cellular and functional magnetic resonance imaging studies of the hippocampus

Autor: C E, Stern, M E, Hasselmo

Publikováno v: Hippocampus. 9(1)

The importance of the medial temporal lobe in memory has been studied extensively at the neuronal, neural ensemble, and systems level. In this report, we discuss recent systems level neuroimaging results in relation to neurophysiological studies of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2fb3c791ed60a9aa9e682132d1792398
https://pubmed.ncbi.nlm.nih.gov/10088899

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GABA(B) modulation improves sequence disambiguation in computational models of hippocampal region CA3

Autor: V S, Sohal, M E, Hasselmo

Publikováno v: Hippocampus. 8(2)

Computational models of hippocampal region CA3 were used to study the role of theta rhythm in storage and retrieval of temporal sequences of neuronal activity patterns. Retrieval of multiple overlapping temporal sequences requires a mechanism for dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76eb8154059a094a001cb650479b5449
https://pubmed.ncbi.nlm.nih.gov/9572723

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A computational model of the progression of Alzheimer's disease

Autor: M E, Hasselmo

Publikováno v: M.D. computing : computers in medical practice. 14(3)

Computational modeling allows analysis of the role of network dynamics in the initiation and progression of neuropathology in Alzheimer's disease. The model focuses on a final common breakdown in function, termed runaway synaptic modification. This p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::506aebed096d40e08f4a9649e60f0986
https://pubmed.ncbi.nlm.nih.gov/9151508

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Encoding and retrieval of episodic memories: role of cholinergic and GABAergic modulation in the hippocampus

Autor: M E, Hasselmo, B P, Wyble, G V, Wallenstein

Publikováno v: Hippocampus. 6(6)

This research focuses on linking episodic memory function to the cellular physiology of hippocampal neurons, with a particular emphasis on modulatory effects at cholinergic and gamma-aminobutyric acid B receptors. Drugs which block acetylcholine rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f0adeab7dd03fd2a1bd6b8a69e093c78
https://pubmed.ncbi.nlm.nih.gov/9034856

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