Zobrazeno 1 - 10
of 44
pro vyhledávání: '"M E, Haberland"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 2, Pp 324-342 (1997)
Malondialdehyde, a product of lipid peroxidation, produces threshold conversion of low density lipoprotein (LDL) to a form recognized by type I and type II scavenger receptors of monocyte-macrophages. To investigate whether localized domains of human
Externí odkaz:
https://doaj.org/article/24df8c591ac34349b145fb69a646d994
Autor:
Peter Tontonoz, Antonio Castrillo, Genhong Cheng, Sagar A. Vaidya, M E Haberland, Sean B. Joseph, Alan M. Fogelman
Publikováno v:
Molecular Cell. 12:805-816
The liver X receptors (LXR) alpha and beta are regulators of cholesterol metabolism and determinants of atherosclerosis susceptibility. Viral and bacterial pathogens have long been suspected to be modulators of atherogenesis; however, mechanisms link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5aed1d468a6f086df92c281a35cee91
https://doi.org/10.1016/s1097-2765(03)00384-8
https://doi.org/10.1016/s1097-2765(03)00384-8
Autor:
Tapani Ronni, M E Haberland, Genhong Cheng, Michael Haykinson, Stephen T. Smale, Vishal Agarwal
Publikováno v:
Molecular and Cellular Biology. 23:2543-2555
Toll-like receptor 4 (TLR4) mediates the host response to lipopolysaccharide (LPS) by promoting the activation of pro- and anti-inflammatory cytokine genes. To activate each gene, numerous signal transduction pathways are required. The adaptor protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c509351ad79c3289b0bc2eaa5c2483
https://doi.org/10.1128/mcb.23.7.2543-2555.2003
https://doi.org/10.1128/mcb.23.7.2543-2555.2003
Autor:
Hajir Dadgostar, Robert L. Modlin, Ren Sun, Ting-Ting Wu, M E Haberland, Govinda Rao, Sean E. Doyle, Paul W. Dempsey, Sagar A. Vaidya, Genhong Cheng, Ryan M. O'Connell
Publikováno v:
Immunity. 17:251-263
We have identified a subset of genes that is specifically induced by stimulation of TLR3 or TLR4 but not by TLR2 or TLR9. Further gene expression analyses established that upregulation of several primary response genes was dependent on NF-kappaB, com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b41333cf17cbe91f0113da8cbdb3590
https://doi.org/10.1016/s1074-7613(02)00390-4
https://doi.org/10.1016/s1074-7613(02)00390-4
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 4, Pp 605-619 (2001)
The detailed morphology of macrophages involved in the uptake and intracellular processing of low density lipoprotein (LDL) and, ultimately, formation of macrophage-derived foam cells of atherosclerotic lesions has long fascinated investigators. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ebf3d8d841ff5415074cad1249ab10
https://doi.org/10.1016/s0022-2275(20)31170-6
https://doi.org/10.1016/s0022-2275(20)31170-6
Publikováno v:
Journal of Lipid Research, Vol 22, Iss 1, Pp 63-71 (1981)
We have recently shown that cultured human monocyte-macrophages degraded 125I-labeled low density lipoprotein (125I-nativeee-LDL) by a saturable high-affinity process with maximal velocity at 25-30 microgram protein/ml (Fogelman et al., 1980, Proc. N
Externí odkaz:
https://doaj.org/article/ebe878a45ef24df090cc71687808cb06
Publikováno v:
Journal of Lipid Research, Vol 22, Iss 7, Pp 1131-1141 (1981)
Improved techniques of cell isolation resulted in 90 to 100 million monocytes from a single donor. Addition of low density lipoprotein (LDL) to to cultures of these cells resulted in the down regulation of LDL receptor activity. Addition of malondial
Externí odkaz:
https://doaj.org/article/71f1897a0dea470da1a30c299962c22c
Autor:
M E Haberland, David P. Hajjar
Publikováno v:
Journal of Biological Chemistry. 272:22975-22978
During the pathogenesis of atherosclerosis, inflammatory cells such as the monocyte-derived macrophage accumulate in the vessel wall where they release cytokines. Initially, cytokines may assist in CE removal of lipoprotein-derived cholesterol/CE hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2958c35fea1c5d72b0f81ac042a40d18
https://doi.org/10.1074/jbc.272.37.22975
https://doi.org/10.1074/jbc.272.37.22975
Autor:
Judith A. Berliner, A M Fogelman, Jeong Ai Kim, M E Haberland, Farhad Parhami, E Wayner, Mary C. Territo, C W Smith, T M Carlos
Publikováno v:
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 14:427-433
Treatment of rabbit aortic endothelial cells, human umbilical vein endothelial cells, and human aortic endothelial cells for 4 hours with minimally oxidized low-density lipoprotein (MM-LDL) induced the adhesion of monocytes but not neutrophils or lym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2d17b67e8e21476e02ddc5e5596073
https://doi.org/10.1161/01.atv.14.3.427
https://doi.org/10.1161/01.atv.14.3.427
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 6, Pp 776-778 (1985)
We describe in this study a reliable method for the breeding of the Watanabe heritable hyperlipidemic (WHHL) rabbit. Placing a male and a female WHHL rabbit in the same cage for the purpose of mating resulted in only two pregnancies out of a total of
Externí odkaz:
https://doaj.org/article/834c477ceaba4d008cbc4e2325e6239b