Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M E, Gruys"'
Publikováno v:
The Journal of Immunology. 152:5776-5784
These studies investigate the effects of exogenously administered recombinant human IL-7 (rhIL-7) on mouse leukocyte subsets in vivo in normal and tumor-bearing mice. The administration of rhIL-7 to normal mice caused a pronounced leukocytosis (three
Publikováno v:
Biotherapy. 3:219-232
Lymphokine activated killer (LAK) cells administered in combination with interleukin 2 (IL2) can mediate antitumor activity in tumor-bearing mice and advanced cancer patients. Relatively little is known about the mechanism by which adoptively transfe
Autor:
M E, Gruys, T C, Back, J, Subleski, T A, Wiltrout, J K, Lee, L, Schmidt, M, Watanabe, R, Stanyon, J M, Ward, J M, Wigginton, R H, Wiltrout
Publikováno v:
Cancer research. 61(16)
Interleukin-2-based regimens of biological therapy have shown some clinical promise for the treatment of kidney cancer in humans, although the mechanisms responsible for tumor regression occurring in these patients remain unclear. Preclinical insight
Autor:
K L, Komschlies, T T, Back, T A, Gregorio, M E, Gruys, G, Damia, R H, Wiltrout, C R, Faltynek
Publikováno v:
Immunology series. 61
Autor:
G, Damia, K L, Komschlies, H, Futami, T, Back, M E, Gruys, D L, Longo, J R, Keller, F W, Ruscetti, R H, Wiltrout
Publikováno v:
Cancer research. 52(15)
Previous studies have demonstrated that interleukin 1 (IL-1) can protect most mice from the acute lethal toxicity mediated by high doses of radiation and/or some chemotherapeutic drugs. The results presented herein demonstrate that the pretreatment o
Autor:
H, Futami, L A, Eader, K L, Komschlies, R, Bull, M E, Gruys, J R, Ortaldo, H A, Young, R H, Wiltrout
Publikováno v:
Cancer research. 51(24)
Flavone-8-acetic acid (FAA) is a flavonoid drug that augments mouse natural killer activity, induces cytokine gene expression, and synergizes with recombinant interleukin 2 for the treatment of murine renal cancer. However, FAA has been largely inact
Publikováno v:
The Journal of Immunology. 143:372-378
A variety of biologic response modifiers (BRM) can potently augment NK activity in nonlymphoid organs. By using the liver as a model organ, we have shown that this augmentation of organ-associated NK activity is coincident with a 10- to 15-fold incre
Autor:
Shi, Wen, Mirza, Sameer, Kuss, Mitchell, Liu, Bo, Hartin, Andrew, Wan, Shibiao, Kong, Yunfan, Mohapatra, Bhopal, Krishnan, Mena, Band, Hamid, Band, Vimla, Duan, Bin
Publikováno v:
Advanced Healthcare Materials; Oct2023, Vol. 12 Issue 26, p1-16, 16p
Autor:
Winterberg, Chase A.1 (AUTHOR) cwinterberg@hoganassessments.com, Brummel, Bradley J.2 (AUTHOR), Ayres, Thomas B.2 (AUTHOR), Kerr, Ali J.3 (AUTHOR)
Publikováno v:
Industrial & Organizational Psychology. Sep2021, Vol. 14 Issue 3, p325-330. 6p.