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Autor:
James W.F. Catto, Robert A. Gardiner, Freddie C. Hamdy, Guido Jenster, Elena S. Martens-Uzunova, Helen E. Bryant, Martin Lavin, Sheila Blizard, Arndt Hartmann, Robert Stoehr, Saiful Miah, Karl Pang, Zhongming Zhao, Raymond Clarke, Ishtiaq Rehman, Ross M. Drayton
Suppl Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e51d2b9ee2f8cac2d41de161e336e17
https://doi.org/10.1158/1055-9965.22438111
https://doi.org/10.1158/1055-9965.22438111
Autor:
James WF. Catto, Helen E. Bryant, Arndt Hartmann, Simone Bertz, Stefan Peter, Ewa Dudziec, Ross M. Drayton
Purpose: Resistance to cisplatin-based chemotherapy is a major obstacle to bladder cancer treatment. We aimed to identify microRNAs (miRNA) that are dysregulated in cisplatin-resistant disease, ascertain how these contribute to a drug-resistant pheno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaaa74e92bca6187060c1bb26d937539
https://doi.org/10.1158/1078-0432.c.6522366
https://doi.org/10.1158/1078-0432.c.6522366
Autor:
James W.F. Catto, Robert A. Gardiner, Freddie C. Hamdy, Guido Jenster, Elena S. Martens-Uzunova, Helen E. Bryant, Martin Lavin, Sheila Blizard, Arndt Hartmann, Robert Stoehr, Saiful Miah, Karl Pang, Zhongming Zhao, Raymond Clarke, Ishtiaq Rehman, Ross M. Drayton
Suppl Figures 1-8. Supplementary Figure 1. Identification of the PCA3-shRNA2 hairpin. (a). Predicted hairpin of PCA3 RNA2. The bases in red are those identified within the prostate RNA transcriptome. (b). BLAST results of the 98bp fragment derived fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d4ed62361fab4030392994768556f1
https://doi.org/10.1158/1055-9965.22438108.v1
https://doi.org/10.1158/1055-9965.22438108.v1
Autor:
James W.F. Catto, Robert A. Gardiner, Freddie C. Hamdy, Guido Jenster, Elena S. Martens-Uzunova, Helen E. Bryant, Martin Lavin, Sheila Blizard, Arndt Hartmann, Robert Stoehr, Saiful Miah, Karl Pang, Zhongming Zhao, Raymond Clarke, Ishtiaq Rehman, Ross M. Drayton
Background: PCA3 is a long noncoding RNA (lncRNA) with unknown function, upregulated in prostate cancer. LncRNAs may be processed into smaller active species. We hypothesized this for PCA3.Methods: We computed feasible RNA hairpins within the BMCC1 g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e512b30d91dc7b4d0ed5b72b4ab986f
https://doi.org/10.1158/1055-9965.c.6516211.v1
https://doi.org/10.1158/1055-9965.c.6516211.v1
Autor:
James WF Catto, Wei Chen, Aidan Noon, Callum P. Rakhit, Ross M. Drayton, Edyta Borkowska, Stefan Peter
Supplemental tables 1 - 5. Supplemental tables reporting lncRNA microarray data, and details including gene ontology for selected candidates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fef748cd64ad7bd08171691155c853d
https://doi.org/10.1158/1078-0432.22456934.v1
https://doi.org/10.1158/1078-0432.22456934.v1
Autor:
James WF. Catto, Helen E. Bryant, Arndt Hartmann, Simone Bertz, Stefan Peter, Ewa Dudziec, Ross M. Drayton
PDF file - 42KB, Tumour and patient information and miR-27a/b and SLC7A11 mRNA expression data from the 139 patient cohort used to generate figure 6 a, b.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176dee7957fa84c9febda6c363561290
https://doi.org/10.1158/1078-0432.22452030
https://doi.org/10.1158/1078-0432.22452030
Autor:
James W.F. Catto, Robert A. Gardiner, Freddie C. Hamdy, Guido Jenster, Elena S. Martens-Uzunova, Helen E. Bryant, Martin Lavin, Sheila Blizard, Arndt Hartmann, Robert Stoehr, Saiful Miah, Karl Pang, Zhongming Zhao, Raymond Clarke, Ishtiaq Rehman, Ross M. Drayton
Suppl. Tables 1-3. Supplementary table 1. Predicted hairpin RNAs within PCA3 and BMCC1. Supplementary table 2. Predicted mRNA targets for PCA3-shRNA2. Supplementary table 3. Primers and condition used to detect target mRNAs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8d04ef2ccb13d7a9ff9394ffb38d18
https://doi.org/10.1158/1055-9965.22438105
https://doi.org/10.1158/1055-9965.22438105
Autor:
James WF Catto, Wei Chen, Aidan Noon, Callum P. Rakhit, Ross M. Drayton, Edyta Borkowska, Stefan Peter
Purpose: Loss of epigenetic gene regulation through altered long noncoding RNA (lncRNA) expression seems important in human cancer. LncRNAs have diagnostic and therapeutic potential, and offer insights into the biology disease, but little is known of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fdfa4c6c3607820edbecd952075c96a
https://doi.org/10.1158/1078-0432.c.6523460
https://doi.org/10.1158/1078-0432.c.6523460
Autor:
James WF Catto, Wei Chen, Aidan Noon, Callum P. Rakhit, Ross M. Drayton, Edyta Borkowska, Stefan Peter
Supplemental figures 1 - 8. Supplemental figures reporting the distribution and fold changes of lncRNA in UCC, together with the outcomes from experiments to understand their function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9304d5ef7ba3a5a235a7706c1d19df
https://doi.org/10.1158/1078-0432.22456937.v1
https://doi.org/10.1158/1078-0432.22456937.v1